Patents by Inventor Che-Shen C. Tomich

Che-Shen C. Tomich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030180821
    Abstract: The present invention provides methods of identifying agents that bind gene products critical for the survival of microbes, preferably Staphylococcus microbes, including agents that interfere with the expression of such gene products and agents that interfere with the function of such gene products.
    Type: Application
    Filed: May 2, 2003
    Publication date: September 25, 2003
    Applicant: PHARMACIA & UPJOHN COMPANY
    Inventors: Che-Shen C. Tomich, Cheryl L. Quinn, Staffan Arvidson, John E. Mott, Douglas W. Harris
  • Publication number: 20030087321
    Abstract: The present invention provides methods of identifying agents that bind gene products critical for the survival of microbes, preferably Staphylococcus microbes, including agents that interfere with the expression of such gene products and agents that interfere with the function of such gene products.
    Type: Application
    Filed: September 28, 2001
    Publication date: May 8, 2003
    Inventors: Che-Shen C. Tomich, Cheryl L. Quinn, Staffan Arvidson, John E. Mott, Douglas W. Harris
  • Publication number: 20020168697
    Abstract: The present invention provides methods of identifying antimicrobial agents that target genes essential for the survival of Staphylococcus bacteria, including antimicrobial agents that interfere with the expression of essential coding sequence products and antimicrobial agents that interfere with the function of essential coding sequence products.
    Type: Application
    Filed: April 6, 2001
    Publication date: November 14, 2002
    Inventors: Che-Shen C. Tomich, Cheryl Quinn, Staffan Arvidson
  • Patent number: 5268284
    Abstract: Provided are ribosome binding sites having an increased number of adenine (A) and thymidine (T) residues as compared to the naturally occurring ribosome binding sites from which they are derived or to which they are related, which allow high level expression of genes encoding heterologous polypeptides, particularly somatotropins, operatively linked thereto.
    Type: Grant
    Filed: August 27, 1990
    Date of Patent: December 7, 1993
    Assignee: The Upjohn Company
    Inventors: Che-Shen C. Tomich, Mary K. Olsen
  • Patent number: 5240837
    Abstract: This invention discloses novel species of cDNAs encoding somatotropins, novel dual replicon vectors, hosts for such vectors and hosts for expressing the somatotropins encoded by such cDNAs.
    Type: Grant
    Filed: August 18, 1989
    Date of Patent: August 31, 1993
    Assignee: The Upjohn Company
    Inventors: Che-Shen C. Tomich, Eric R. Olson, John E. Mott