Abstract: An optical detection device is applied to an organism and includes a light emitting module, an optical detection module and an operation processor. The light emitting module includes a plurality of light emitters arranged along a first direction. The optical detection module includes a plurality of optical sensors arranged along a second direction and symmetrically relative to the light emitting module. The second direction is substantially different from the first direction. The optical sensors are substantially placed more outward from a center of the optical detection device than the light emitters. The operation processor is electrically connected to the optical detection module. The operation processor is adapted to analyze signal variation in the plurality of light emitters acquired by each of the plurality of optical sensors for determining a physiological feature of the organism.