Patents by Inventor Chee Furng Wong

Chee Furng Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS TO MODULATE LYSINE VARIANT DISTRIBUTION
    Publication number: 20170349655
    Abstract: The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the distribution or amount of lysine variants expressed by host cells, as well as to compositions and processes for controlling the amount of lysine variants present in purified preparations.
    Type: Application
    Filed: June 19, 2017
    Publication date: December 7, 2017
    Applicant: AbbVie Inc.
    Inventors: Kartik Subramanian, Mayda Perez Thiele, Xiaobei Zeng, Chee Furng Wong, Christopher M. Chumsae
  • Methods to modulate lysine variant distribution
    Patent number: 9708400
    Abstract: The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the distribution or amount of lysine variants expressed by host cells, as well as to compositions and processes for controlling the amount of lysine variants present in purified preparations.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: July 18, 2017
    Assignee: ABBVIE, INC.
    Inventors: Kartik Subramanian, Mayda Perez Thiele, Xiaobei Zeng, Chee Furng Wong, Christopher M. Chumsae
  • MODULATED LYSINE VARIANT SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME
    Publication number: 20170121403
    Abstract: The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated lysine variant species compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF? is detrimental, are also provided.
    Type: Application
    Filed: November 16, 2016
    Publication date: May 4, 2017
    Applicant: AbbVie, Inc.
    Inventors: Kartik SUBRAMANIAN, Mayda Perez THIELE, Xiaobei ZENG, Chee Furng WONG, Zehra KAYMAKCALAN, Ying JING, Christopher M. CHUMSAE
  • Modulated lysine variant species compositions and methods for producing and using the same
    Patent number: 9499616
    Abstract: The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated lysine variant species compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF? is detrimental, are also provided.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: November 22, 2016
    Assignee: ABBVIE INC.
    Inventors: Kartik Subramanian, Mayda Perez Thiele, Xiaobei Zeng, Chee Furng Wong, Zehra Kaymakcalan, Ying Jing, Christopher M. Chumsae
  • MODULATED LYSINE VARIANT SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME
    Publication number: 20160237150
    Abstract: The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated lysine variant species compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF? is detrimental, are also provided.
    Type: Application
    Filed: October 27, 2015
    Publication date: August 18, 2016
    Inventors: Kartik Subramanian, Mayda Perez Thiele, Xiaobei Zeng, Chee Furng Wong, Zehra Kaymakcalan, Ying Jing, Christopher M. Chumsae
  • METHODS TO MODULATE LYSINE VARIANT DISTRIBUTION
    Publication number: 20160046708
    Abstract: The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the distribution or amount of lysine variants expressed by host cells, as well as to compositions and processes for controlling the amount of lysine variants present in purified preparations.
    Type: Application
    Filed: October 27, 2015
    Publication date: February 18, 2016
    Inventors: Kartik Subramanian, Mayda Perez Thiele, Xiaobei Zeng, Chee Furng Wong, Christopher M. Chumsae
  • Modulated lysine variant species compositions and methods for producing and using the same
    Patent number: 9181337
    Abstract: The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated lysine variant species compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF? is detrimental, are also provided.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: November 10, 2015
    Assignee: AbbVie, Inc.
    Inventors: Kartik Subramanian, Mayda Perez Thiele, Xiaobei Zeng, Chee Furng Wong, Zehra Kaymakcalan, Ying Jing, Christopher Chumsae
  • Methods to modulate lysine variant distribution
    Patent number: 9181572
    Abstract: The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the distribution or amount of lysine variants expressed by host cells, as well as to compositions and processes for controlling the amount of lysine variants present in purified preparations.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: November 10, 2015
    Assignee: AbbVie, Inc.
    Inventors: Kartik Subramanian, Mayda Perez, Xiaobei Zeng, Chee Furng Wong, Christopher Chumsae
  • MODULATED LYSINE VARIANT SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME
    Publication number: 20150110775
    Abstract: The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated lysine variant species compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF? is detrimental, are also provided.
    Type: Application
    Filed: November 12, 2013
    Publication date: April 23, 2015
    Inventors: Kartik SUBRAMANIAN, Mayda PEREZ THIELE, Xiaobei ZENG, Chee Furng WONG, Zehra KAYMAKCALAN, Ying JING, Christopher CHUMSAE
  • METHODS TO MODULATE LYSINE VARIANT DISTRIBUTION
    Publication number: 20130280274
    Abstract: The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the distribution or amount of lysine variants expressed by host cells, as well as to compositions and processes for controlling the amount of lysine variants present in purified preparations.
    Type: Application
    Filed: March 14, 2013
    Publication date: October 24, 2013
    Applicant: ABBVIE INC.
    Inventors: Kartik Subramanian, Mayda Perez, Xiaobei Zeng, Chee Furng Wong
  • CHINESE HAMSTER APOPTOSIS-RELATED GENES
    Publication number: 20110318317
    Abstract: Provided is an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.
    Type: Application
    Filed: April 13, 2011
    Publication date: December 29, 2011
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: CHEE FURNG WONG, MIRANDA GEK SIM YAP
  • CHINESE HAMSTER APOPTOSIS-RELATED GENES
    Publication number: 20110318316
    Abstract: Provided is an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.
    Type: Application
    Filed: April 13, 2011
    Publication date: December 29, 2011
    Applicant: Agency for Science, Technology and Research
    Inventors: Chee Furng WONG, Miranda Gek Sim Yap
  • CHINESE HAMSTER APOPTOSIS-RELATED GENES
    Publication number: 20110318831
    Abstract: Provided is an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.
    Type: Application
    Filed: April 13, 2011
    Publication date: December 29, 2011
    Applicant: Agency for Science, Technology and Research
    Inventors: Chee Furng WONG, Miranda Gek Sim Yap
  • CHINESE HAMSTER APOPTOSIS-RELATED GENES
    Publication number: 20110129927
    Abstract: Provided is an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.
    Type: Application
    Filed: November 15, 2010
    Publication date: June 2, 2011
    Applicant: Agency for Science, Technology and Research
    Inventors: Chee Furng Wong, Miranda Gek Sim Yap
  • Chinese hamster apoptosis-related genes
    Patent number: 7846894
    Abstract: Provided is an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: December 7, 2010
    Assignee: Agency for Science, Technology and Research
    Inventors: Chee Furng Wong, Miranda Gek Sim Yap
  • Chinese hamster apoptosis-related genes
    Publication number: 20080295190
    Abstract: Provided is an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.
    Type: Application
    Filed: July 2, 2007
    Publication date: November 27, 2008
    Inventors: Chee Furng Wong, Miranda Gek Sim Yap