Patents by Inventor Chee-Yeun Chung

Chee-Yeun Chung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and uses thereof
    Patent number: 12275723
    Abstract: The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
    Type: Grant
    Filed: September 27, 2023
    Date of Patent: April 15, 2025
    Assignee: JANSSEN PHARMACEUTICA NV
    Inventors: Matthew Lucas, Bertrand Le Bourdonnec, Iwona Wrona, Bhaumik Pandya, Parcharee Tivitmahaisoon, Kerem Ozboya, Benjamin Vincent, Daniel Tardiff, Jeff Piotrowski, Eric Solis, Robert Scannevin, Chee-Yeun Chung, Rebecca Aron, Kenneth Rhodes
  • GENE EDITING METHOD FOR INHIBITING ABERRANT SPLICING IN STATHMIN 2 (STMN2) TRANSCRIPT
    Publication number: 20240301447
    Abstract: A method for inhibiting aberrant splicing in a Stathmin-2 (STMN2) transcript, the method comprising: genetically editing a STMN2 gene in a cell to delete (a) one or more nucleotides in a 3? splice site of intron 1, wherein the 3? splice site is adjacent to exon 2a, (b) one or more nucleotides in a region of intron 1 that is adjacent to the 3? splice site, or both (a) and (b), thereby inhibiting production of STMN2 transcripts including exon 2a and improving production of functional STMN2 transcripts in the cell. Also provided herein are gene editing systems for genetic modification of the STMN2 gene.
    Type: Application
    Filed: February 15, 2024
    Publication date: September 12, 2024
    Applicant: Arbor Biotechnologies, Inc.
    Inventors: Ryan Phillip Abo, Chee Yeun Chung, Anthony Garrity, Priscilla Davidson Negraes
  • Methods for building genomic networks and uses thereof
    Patent number: 12068059
    Abstract: Disclosed are methods, systems, cells and compositions directed to modeling a physiologic or pathologic process in an animal using a set of yeast genes analogous to a set of animal genes and augmenting the physiologic or pathologic process in the animal with predicted gene interactions based on the interactions between the set of yeast genes. Also disclosed are methods of screening for and using therapeutics for neurodegenerative proteinopathies.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: August 20, 2024
    Assignees: Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
    Inventors: Vikram Khurana, Chee Yeun Chung, Susan Lindquist, Bonnie A. Berger, Ernest Fraenkel, Jian Peng
  • COMPOUNDS AND USES THEREOF
    Publication number: 20240124435
    Abstract: The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
    Type: Application
    Filed: September 27, 2023
    Publication date: April 18, 2024
    Applicant: JANSSEN PHARMACEUTICA NV
    Inventors: Matthew Lucas, Bertrand Le Bourdonnec, Iwona Wrona, Bhaumik Pandya, Parcharee Tivitmahaisoon, Kerem Ozboya, Benjamin Vincent, Daniel Tardiff, Jeff Piotrowski, Eric Solis, Robert Scannevin, Chee-Yeun Chung, Rebecca Aron, Kenneth Rhodes
  • Compounds and uses thereof
    Patent number: 11873298
    Abstract: The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: January 16, 2024
    Assignee: JANSSEN PHARMACEUTICA NV
    Inventors: Matthew Lucas, Bertrand Le Bourdonnec, Iwona Wrona, Bhaumik Pandya, Parcharee Tivitmahaisoon, Kerem Ozboya, Benjamin Vincent, Daniel Tardiff, Jeff Piotrowski, Eric Solis, Robert Scannevin, Chee-Yeun Chung, Rebecca Aron, Kenneth Rhodes
  • METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
    Publication number: 20220040167
    Abstract: The present disclosure provides compounds and methods useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
    Type: Application
    Filed: April 9, 2021
    Publication date: February 10, 2022
    Inventors: Benjamin Matteson VINCENT, Daniel Forrest TARDIFF, Jeff Scott PIOTROWSKI, Eric SOLIS, Robert Hughie SCANNEVIN, Chee-Yeun CHUNG, Rebecca ARON, Bertrand LE BOURDONNEC, Matthew LUCAS, Kenneth RHODES
  • Cellular discovery platform for neurodegenerative diseases
    Patent number: 11047848
    Abstract: In some aspects, a cross-species platform useful for drug discovery in neurodegenerative diseases is described.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: June 29, 2021
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Susan L. Lindquist, Vikram Khurana, Chee-Yeun Chung
  • Methods for the treatment of neurological disorders
    Patent number: 10973810
    Abstract: The present disclosure provides compounds and methods useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: April 13, 2021
    Assignee: Yumanity Therapeutics, Inc.
    Inventors: Benjamin Vincent, Daniel Tardiff, Jeff Piotrowski, Eric Solis, Robert Scannevin, Chee-Yeun Chung, Rebecca Aron, Bertrand Le Bourdonnec, Matthew Lucas, Kenneth Rhodes
  • COMPOUNDS AND USES THEREOF
    Publication number: 20200262828
    Abstract: The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
    Type: Application
    Filed: October 24, 2018
    Publication date: August 20, 2020
    Inventors: Matthew LUCAS, Bertrand LE BOURDONNEC, Iwona WRONA, Bhaumik PANDYA, Parcharee TIVITMAHAISOON, Kerem OZBOYA, Benjamin VINCENT, Daniel TARDIFF, Jeff PIOTROWSKI, Eric SOLIS, Robert SCANNEVIN, Chee-Yeun CHUNG, Rebecca ARON, Kenneth RHODES
  • METHODS FOR BUILDING GENOMIC NETWORKS AND USES THEREOF
    Publication number: 20200265917
    Abstract: Disclosed are methods, systems, cells and compositions directed to modeling a physiologic or pathologic process in an animal using a set of yeast genes analogous to a set of animal genes and augmenting the physiologic or pathologic process in the animal with predicted gene interactions based on the interactions between the set of yeast genes. Also disclosed are methods of screening for and using therapeutics for neurodegenerative proteinopathies.
    Type: Application
    Filed: January 25, 2018
    Publication date: August 20, 2020
    Inventors: Vikram Khurana, Chee Yeun Chung, Susan Lindquist, Bonnie A. Berger, Ernest Fraenkel, Jian Peng
  • COMPOUNDS AND USES THEREOF
    Publication number: 20200010462
    Abstract: The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
    Type: Application
    Filed: October 24, 2017
    Publication date: January 9, 2020
    Inventors: Matthew LUCAS, Bertrand LE BOURDONNEC, Iwona WRONA, Bhaumik PANDYA, Parcharee TIVITMAHAISOON, Kerem OZBOYA, Benjamin VINCENT, Daniel TARDIFF, Jeff PIOTROWSKI, Eric SOLIS, Robert SCANNEVIN, Chee-Yeun CHUNG, Rebecca ARON, Kenneth Rhodes
  • METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
    Publication number: 20180193325
    Abstract: The present disclosure provides compounds and methods useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 12, 2018
    Inventors: Benjamin VINCENT, Daniel TARDIFF, Jeff PIOTROWSKI, Eric SOLIS, Robert SCANNEVIN, Chee-Yeun CHUNG, Rebecca ARON, Bertrand LE BOURDONNEC, Matthew LUCAS, Kenneth RHODES
  • CELLULAR DISCOVERY PLATFORM FOR NEURODEGENERATIVE DISEASES
    Publication number: 20170153226
    Abstract: In some aspects, a cross-species platform useful for drug discovery in neurodegenerative diseases is described.
    Type: Application
    Filed: March 17, 2014
    Publication date: June 1, 2017
    Inventors: Susan L. Lindquist, Vikram Khurana, Chee-Yeun Chung
  • CELLULAR DISCOVERY PLATFORM FOR NEURODEGENERATIVE DISEASES
    Publication number: 20160041149
    Abstract: In some aspects, a cross-species platform useful for drug discovery in neurodegenerative diseases is described.
    Type: Application
    Filed: March 17, 2014
    Publication date: February 11, 2016
    Inventors: Susan L. Lindquist, Vikram Khurana, Chee-Yeun Chung
  • RAB3B for treatment and prevention of Parkinson's disease
    Patent number: 8586558
    Abstract: The invention features methods and compositions for the treatment and prevention of Parkinson's Disease.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: November 19, 2013
    Assignee: The McLean Hospital Corporation
    Inventors: Ole Isacson, Chee Yeun Chung
  • G-substrate for the treatment and prevention of parkinson's disease
    Patent number: 8545834
    Abstract: The invention features methods and compositions for the treatment and prevention of Parkinson's Disease.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: October 1, 2013
    Assignee: The McLean Hospital Corporation
    Inventors: Ole Isacson, Chee-Yeun Chung
  • RAB3B FOR THE TREATMENT AND PREVENTION OF PARKINSON'S DISEASE
    Publication number: 20110129527
    Abstract: The invention features methods and compositions for the treatment and prevention of Parkinson's Disease.
    Type: Application
    Filed: May 15, 2009
    Publication date: June 2, 2011
    Inventors: Dr. Ole Isacson, Chee Yeun Chung
  • G-SUBSTRATE FOR THE TREATMENT AND PREVENTION OF PARKINSON'S DISEASE
    Publication number: 20100203111
    Abstract: The invention features methods and compositions for the treatment and prevention of Parkinson's Disease.
    Type: Application
    Filed: March 11, 2008
    Publication date: August 12, 2010
    Inventors: Ole Isacson, Chee-Yeun Chung