Abstract: The present invention relates in part to hybrid hydrogel scaffolds including a decellularized extracellular matrix (dECM) tissue, and a synthetic polymer. The dECM may include any suitable tissue including for example, lung tissue, heart tissue, heart-lung block tissue, skin tissue, liver tissue, pancreatic tissue, kidney tissue, and the like.

Abstract: The present disclosure generally relates to a formulation. More particularly, the formulation may be applied to skin and/or used in combination with a personal care product to improve absorbance and leakage control of the personal care product, and to promote a more positive feel and comfort through improved skin cleanliness and health.

Abstract: Methods of making, using and applying a composition to an exposed surface are disclosed using a disposable applicator. The method of making the disposable applicator includes forming a back sheet and a liquid permeable substrate. The substrate is secured to the back sheet and a composition is applied to the substrate. The composition is capable of being transferred onto an exposed surface by wiping the substrate against the exposed surface. A seal is formed on at least a portion of the back sheet. The back sheet is then folded upon itself such that the seal extends completely around the substrate to protect the composition. The methods of using and applying a composition to an exposed surface include breaking the seal and opening the back sheet, grasping the back sheet in one hand and wiping the substrate onto the exposed surface.

Abstract: A disposable applicator is disclosed for applying a composition to an exposed surface. The applicator includes a back sheet, a liquid permeable substrate secured to one surface of the back sheet, and a composition applied to the liquid permeable substrate. The composition is capable of being transferred to an exposed surface by wiping the liquid permeable substrate against the exposed surface. The applicator also has a seal formed on at least a portion of an inner surface of the back sheet. The back sheet is then folded upon itself such that the seal extends completely around the perimeter of the substrate and protects the composition.