Abstract: A valve spring fixing device and a plunger pump are disclosed. The valve spring fixing device includes a spring fixing piece, which includes a first supporting surface and a second supporting surface located at two ends of the spring fixing piece, and an intermediate portion located between the first supporting surface and the second supporting surface; and a spring mounting portion connected with the intermediate portion and configured to mount a valve spring, the first supporting surface and the second supporting surface are configured to contact with a valve box to fix the valve spring fixing device.

Abstract: A virtual scene interaction method is disclosed, including displaying a viewing page of a target cloud video, a play screen of a virtual scene being displayed in the target cloud video, the viewing page comprising N interaction triggering marks, an ith interaction triggering mark of the N interaction triggering marks being used for linking to an interaction progress point in the virtual scene, both i and N being positive integers, and i?N; and displaying, when the ith interaction triggering mark is selected, a control page for the virtual scene starting from the interaction progress point linked by the ith interaction triggering mark.

Abstract: An interaction scene starting method includes displaying a play interface of a target video, the target video corresponding to a recorded play of a game; identifying a first interaction progress point of a virtual interaction scene of the game in the target video; obtaining scene interaction data corresponding to the first interaction progress point from a scene interaction server; and displaying a scene interaction image according to the scene interaction data and enabling playing the game from the first interaction progress point.

Abstract: The present invention discloses a high-threshold power semiconductor device and a manufacturing method thereof. The high-threshold power semiconductor device includes, in sequence from bottom to top: a metal drain electrode, a substrate, a buffer layer, and a drift region; further including: a composite column body which is jointly formed by a drift region protrusion, a columnar p-region and a columnar n-region on the drift region, a channel layer, a passivation layer, a dielectric layer, a heavily doped semiconductor layer, a metal gate electrode and a source metal electrode. The composite column body is formed by sequentially depositing a p-type semiconductor layer and an n-type semiconductor layer on the drift region and then etching same. The channel layer and the passivation layer are formed in sequence by deposition. Thus, the above devices are divided into a cell region and a terminal region.

Abstract: Disclosed in the present invention are a pyrazolone-fused pyrimidine compound, and a preparation method and a use therefor. Provided in the present invention is a pyrazolone-fused pyrimidine compound as in formula (I), said compound having better inhibitory activity towards WEE1 kinase.

Abstract: A plunger, a hydraulic end and a plunger pump are disclosed. The plunger includes a plunger body, the plunger body includes a flow channel; a first liquid inlet hole is located in the plunger body and passes through the sidewall of the plunger body; the plunger body includes a first end portion and a second end portion, a flow channel extends from the first end portion to the second end portion, a part of the flow channel close to the first end portion is closed, the flow channel extends to the second end portion and forms a first opening, the first liquid inlet hole is communicated with the flow channel, the first valve assembly is located at the first opening, and is configured to allow fluid to flow out from the flow channel at the first opening and prevent fluid from flowing back to the flow channel from outside.

Abstract: The present invention discloses a kind of xylanase mutant and its preparation method and application, which relates to the technical field of genomic engineering and genetic engineering. Such mutant includes one or more mutants obtained by taking xylanase HwXy110A as female parent to conduct saturation mutagenesis to the site of Gly363. Specifically, relates to obtaining 19 mutants through site-directed mutagenesis, and then conducting yeast expression to them, after that, obtaining two mutants with significantly improved specific activity and thermal stability through screening of thermal stability and catalytic activity; the present invention can significantly improve the thermal stability and catalytic efficiency of xylanase through modifying the site of Gly363, and is of important guiding significance for improving the thermal stability and the catalytic efficiency of the 10th family of xylanases and other glycoside hydrolases as well as lays the foundation for its application in industrial production.

Abstract: A composition contains: (a) a polyorganosiloxane component comprising one or a combination of more than one poly-organosiloxane; (b) a filler treating agent comprising alkyltrialkoxysilane and trialkoxysiloxy-terminated diorganopolysiloxane; (c) 90-98 weight-percent of a combination of thermally conductive fillers comprising: (i) 25-40 weight-percent of thermally conductive filler particles having an average particle size of 70-150 micrometers and selected from one or a combination of aluminum oxide and aluminum nitride particles; (ii) 15-30 weight-percent thermally conductive filler particles having an average particle size in a range of 30-45 micrometers selected from one or a combination of aluminum oxide and aluminum nitride particles; (iii) 25-32 weight-percent aluminum oxide particles having an average particle size in a range of 1-5 micrometers; and (iv) 10-15 weight-percent thermally conductive filler particles having an average particle size in a range of 0.1 to 0.

Abstract: A phenyl-containing compound, an intermediate thereof, a preparation method therefor and an application thereof. Provided is a compound represented by formula I or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4 and R5 are independently hydrogen, C1-C6 alkyl, C1-C6 alkoxy or C(?O)OR8; where R8 is C1-C4 alkyl; R6 is (II), (III) or (IV); and R7 is —OH, —NH2, —NHCH3, —N(CH3)2 or C1-4 alkoxy. The compound has a low critical micelle concentration (CMC) and good dilution resistance and is capable of enclosing an insoluble drug to form a small-molecule micelle having a high drug loading capacity and good stability.

Abstract: Disclosed are a pyrazolone-fused pyrimidine compound, a preparation method for same and applications thereof. Provided in the present invention is the pyrazolone-fused pyrimidine compound as represented by formula (II). The compound has improved inhibitory activity with respect to WEE1 kinase.

Abstract: The present invention discloses a kind of xylanase mutant and its preparation method and application, which relates to the technical field of genomic engineering and genetic engineering. Such mutant includes one or more mutants obtained by taking xylanase HwXyl10A as female parent to conduct saturation mutagenesis to the site of Gly363. Specifically, relates to obtaining 19 mutants through site-directed mutagenesis, and then conducting yeast expression to them, after that, obtaining two mutants with significantly improved specific activity and thermal stability through screening of thermal stability and catalytic activity; the present invention can significantly improve the thermal stability and catalytic efficiency of xylanase through modifying the site of Gly363, and is of important guiding significance for improving the thermal stability and the catalytic efficiency of the 10th family of xylanases and other glycoside hydrolases as well as lays the foundation for its application in industrial production.

Abstract: A multi-zone end effector assembly is described in the present disclosure. As a non-limiting example, the multi-zone end effector assembly comprises a manifold that comprises a first interior chamber and a second interior chamber. A first port connects to the first interior chamber, and a second port connects to the second interior chamber. A first compression cup region can be connected to the first interior chamber. The first compression cup region is in air connection with the first port. The first compression cup region is configured to be independently activated in order to create a first vacuum zone. A second compression cup region is connected to the second interior chamber. The second compression region cup is in air connection with the second port. The second compression cup region is configured to be independently activated in order to create a second vacuum zone.

Abstract: An apparatus for unloading packages (103) from a container (106), the apparatus comprising: a conveyor system (109); a supporting frame (209) mounted on the conveyor system, the supporting frame being substantially perpendicular to a length of the conveyor system; and an end effector assembly (112) coupled to the supporting frame and being moveable about a horizontal axis relative to the supporting frame, the end effector assembly comprising: a manifold plate (203) extending along a vertical plane that is generally parallel to the supporting frame; a gripping component (115) coupled to and extending outwardly from the manifold plate along the horizontal axis relative to the supporting frame, the gripping component being configured to engage with one or more of the packages stacked in the container; and one or more sensors (303), the one or more sensors being configured to determine a distance between the end effector assembly and the packages.

Abstract: Disclosed are various embodiments for an automated package unloading system. An automated package unloading system can include an end effector supported by a supporting frame which is mounted to a conveyor system. The end effector and/or the conveyor can be configured to move into and out of a container containing stacked packages. The end effector can be configured to attach to the packages and pull the packages from their original position. The end effector can further be configured to release the packages onto the underlying conveyor.

Abstract: Disclosed are various embodiments for an automated package unloading system. An automated package unloading system can include an end effector supported by a supporting frame which is mounted to a conveyor system. The end effector and/or the conveyor can be configured to move into and out of a container containing stacked packages. The end effector can be configured to attach to the packages and pull the packages from their original position. The end effector can further be configured to release the packages onto the underlying conveyor.