Abstract: Disclosed are methods of isolating a TCR having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation, the method comprising: identifying one or more genes in the nucleic acid of a cancer cell of a patient, each gene containing a cancer-specific mutation that encodes a mutated amino acid sequence; inducing autologous APCs of the patient to present the mutated amino acid sequence; co-culturing autologous T cells of the patient with the autologous APCs that present the mutated amino acid sequence; selecting the autologous T cells; and isolating a nucleotide sequence that encodes the TCR from the selected autologous T cells, wherein the TCR has antigenic specificity for the mutated amino acid sequence encoded by the cancer-specific mutation. Also disclosed are related methods of preparing a population of cells, populations of cells, TCRs, pharmaceutical compositions, and methods of treating or preventing cancer.

Abstract: Disclosed herein is a method of detecting the presence or absence of an analyte in a test sample, based on the use of motion resistant particle for example non-magnetic particle coated with first sensing element for the analyte and force driven particle for example superparamagnetic particle coated with a second sensing element for the analyte so as to form a motion resistant particle-analyte-force driven particle conjugate. A viscous medium is added to the mixture and a force such as magnetic force is applied to provide separation of the conjugate for quantification. Disclosed herein are also a sensing kit, a system for detecting the presence or absence of an analyte in a test sample and the use of the kit or the system thereof.

Abstract: Provided are an information transmission and reception method and apparatus. The method includes: determining a transmission manner of a V2X service duplication to be transmitted; selecting a PC5 air interface carrier for transmitting the V2X service duplication according to a rule corresponding to the transmission manner; and transmitting the V2X service duplication on the selected PC5 air interface carrier.

Abstract: An electronic device is provided, including a housing, a first slot, a second slot, and a circuit board. The first and second slots are formed on the housing and spaced apart from each other. The circuit board is disposed in the housing and includes a first antenna structure and a second antenna structure. The first antenna structure has a Z-shaped conductive body, and the second antenna structure includes a microstrip portion and a base portion. The base portion is electrically connected to the conductive body, and the microstrip portion is spaced apart from the base portion.

Abstract: Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.

Abstract: The invention relates to a stand for hand-held device and a protective case comprising the stand. The stand comprises a first plate, a second plate and a lifting device between the first plate and the second plate. The inner end of the first plate and the inner end of the second plate are pivoted with each other to form a pivoting portion. The lifting device controls the free end portion of the first plate and the free end portion of the second plate to be close to or away from each other. The lifting device comprises a limiting device and an elastic sheet, thereby when one end of the elastic sheet moves along the length direction of the second plate, and construes a first displacement relative to the pivoting portion, the free end portion of the first plate is driven up to form a second displacement relative to the free end portion of the second plate.

Abstract: The invention relates to a stand for a hand-held device and a protective case comprising the stand. The stand comprises a first base, a second base, a first elastic sheet, a second elastic sheet and a limiting device. The first ends of the first elastic sheet and the second elastic sheet are respectively arranged on the two sides of the first base. The limiting device enables the second end of the first base and the second end of the second base to slide separately and not overlap each other within a limited range. When the second end of the first elastic sheet and the second end of the second elastic sheet carry out a first relative displacement, the first base and the second base forms a second relative displacement.

Abstract: A slide assembly includes a channel member including a stop recess having a front end and a rear end; a slide member including a sliding first portion, a sliding second portion, a slot, and a connection portion on the sliding first portion, the slide member being configured to move in the channel member; and a release mechanism disposed on the slide member and including first and second release member. In a locked state the first limit members of the positioning portion of the first release member engage with the front larger hole of the stop recess, the second limit members of the positioning portion of the first release member engage with the rear smaller hole of the stop recess, and the elastic arm of the second release member engages with the rear smaller hole of the stop recess. A double release mechanism is provided.

Abstract: An image recognition system includes at least one sensor, a memory and a processor. The at least one sensor is configured to capture a plurality of images. The memory is configured to store a plurality of commands. The processor is configured for obtaining the plurality of commands from the memory to perform the following steps: capturing at least two images in the building by at least one sensor. Person detection is performed on at least two images at the first time point to obtain a first feature frame.

Abstract: A rehabilitation system based on brainwave control includes a rehabilitation device, a brainwave device and a control unit. The rehabilitation device includes a power unit and a rehabilitation unit. The control unit is coupled with the rehabilitation device and the brainwave device. In a state where the power unit provides the predetermined output to control the rehabilitation unit to drive the rehabilitation part to move, the control unit receives the brainwave signal and determines whether the brainwave signal is lower than a stimulation threshold. In a state where the brainwave signal is lower than the stimulation threshold, the control unit sends an adjustment signal to control the power unit to adjust the predetermined output to drive the rehabilitation unit to move.

Abstract: The present disclosure generally relates to glyoxalated polyacrylamide (GPAM) compositions, methods of preparation and methods of use thereof, particularly in the paper industry. Moreover, the present disclosure generally pertains to cationic GPAM compositions, methods of preparation and methods of use thereof in papermaking applications and in products such as paper-based products, wherein the cationic GPAM compositions may provide increased wet and/or dry strength to the paper-based products, and wherein such cationic GPAM compositions optionally require a reduced volume of an aqueous carrier for storage or transport compared to a volume of an aqueous carrier needed for conventional GPAMs used in papermaking.

Abstract: The present disclosure generally relates to glyoxalated polyacrylamide (GPAM) products, compositions comprising GPAM products, and methods of use thereof, particularly in the paper industry. Moreover, the present disclosure generally pertains to cationic GPAM products, compositions comprising, and use thereof in papermaking applications and in products such as paper-based products, wherein the cationic GPAM products may provide increased wet and/or dry strength to the paper-based product and wherein such GPAMs optionally can be stored and transported to a papermaking site without the addition of large volumes of aqueous carriers.

Abstract: A level shifter includes a buffer circuit, a first shift circuit, and a second shift circuit. The buffer circuit provides a first signal and a first inverted signal to the first shift circuit, such that the first shift circuit provides a second signal and a second inverted signal to the second shift circuit. The second shift circuit generates a plurality of output signals according to the second signal and the second inverted signal. The first shift circuit includes a plurality of first stacking transistors and a first voltage divider circuit. The first voltage divider circuit is electrically coupled between a first system high voltage terminal and a system low voltage terminal. The first voltage divider circuit is configured to provide a first inner bias to gate terminals of the first stacking transistors.

Abstract: A slide assembly includes a channel member including a stop recess having a front end and a rear end; a slide member including a sliding first portion, a sliding second portion, a slot, and a connection portion on the sliding first portion, the slide member being configured to move in the channel member; and a release mechanism disposed on the slide member and including first and second release member. In a locked state the first limit members of the positioning portion of the first release member engage with the front larger hole of the stop recess, the second limit members of the positioning portion of the first release member engage with the rear smaller hole of the stop recess, and the elastic arm of the second release member engages with the rear smaller hole of the stop recess. A double release mechanism is provided.

Abstract: A microwave coupling moisture content sensor and a method for deriving a linear regression correlation between signal data generated by a microwave moisture content sensor and moisture contents of objects are disclosed. The microwave coupling moisture content sensor includes a microwave resonator and a signal feeding member or a microwave emitting member. An object is placed outside the microwave resonator, and the signal feeding member or the microwave emitting member emits microwaves, which penetrate the object. The resonance frequency and the amplitude of the microwave resonator are measured to obtain the moisture content of the object. Several objects having known moisture contents are detected by the microwave coupling moisture content sensor to obtain corresponding resonance frequency and amplitude.

Abstract: A method for rendering an environment in an electronic game is disclosed. The game comprises a plurality of sessions and the method comprises, during an initiation phase, generating a map for all sessions of the game and dividing the map up into a plurality of sub-regions, each of the sub-regions being allocated to at least one session; and for each session, rendering a current sub-region of the map wherein the current sub-region corresponds to a current session.

Abstract: A server architecture and method for implementing online multi-player games are disclosed, the server architecture comprising regional servers, each of the regional servers having a designated region and configured to perform matchmaking for client devices based on the designated region. The server architecture further comprises a central data server configured to receive an identifier from a client device; select a regional server based on the identifier and the designated regions, and send a regional server ID of the selected regional server to the client device. Wherein the selected regional server is configured to receive from the central data server, player profile data associated with the identifier; and perform matchmaking by grouping the client device in an online play session with other client devices based on the designated region of the selected regional server.

Abstract: A graphical user interface for electronic games is disclosed. The interface comprises a current weapon panel configured to display a first weapon in an active state, and a plurality of spare weapon panels configured to display weapons in the inactive state. The plurality of spare weapon panels is arranged in accordance with the panel ranking values assigned to each spare weapon panel. The selection of any one of the spare weapon panels results in a corresponding weapon in the inactive state, which is displayed on the selected spare weapon panel, being switched to the active state and promoted to the current weapon panel, and the first weapon being switched to the inactive state and relegated to a spare weapon panel. The weapons in the inactive state are dynamically ordered and displayed on the plurality of spare weapon panels according to the panel ranking value of the spare weapon panels and the predicted weapon ranking value.

Abstract: An electronic device is provided, including a housing, a first slot, a second slot, and a circuit board. The first and second slots are formed on the housing and spaced apart from each other. The circuit board is disposed in the housing and includes a first antenna structure and a second antenna structure. The first antenna structure has a Z-shaped conductive body, and the second antenna structure includes a microstrip portion and a base portion. The base portion is electrically connected to the conductive body, and the microstrip portion is spaced apart from the base portion.

Abstract: A method for implementing a multi-player game comprising the steps of receiving at a client application on a client device, a command to perform an action; calculating at the client application, a consequence of the action; and rendering by the client application, the consequence in a first instance of the game. The method further comprises the steps of sending a data package from the client device to a server, the data package comprising the action and the consequence; determining by the server, that the consequence is valid; and disseminating by the server, the data package to other client devices, so that client applications in the other client devices can render the consequence in other instances of the game. Wherein the step of rendering by the client application the consequence in the first instance of the game, is performed prior to the step of determining by the server that the consequence is valid.