Patents by Inventor Chen-Lung Lin

Chen-Lung Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11933945
    Abstract: An optical lens includes a first lens group and a second lens group. The first lens group has at least two lenses that include at least one aspheric lens, the second lens group has at least four lenses that includes at least one aspheric lens, and a total number of lenses with refractive powers in the optical lens is smaller than nine. The first and the second lens groups include a first lens, a second lens, a third lens, a fourth lens, a fifth lens and a sixth lens in order from the magnified side to the minified side. The first lens to the sixth lens have respective refractive powers of negative, negative, positive, positive, negative and positive.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: March 19, 2024
    Assignee: RAYS OPTICS INC.
    Inventors: Ching-Lung Lai, Ying-Hsiu Lin, Chen-Cheng Lee
  • Publication number: 20230134465
    Abstract: Provided is a spinning solution, comprising a cannabidiol powder and an alginate solution. Besides, the present invention further provides an alginate fiber comprising cannabidiol, and the preparation method and the use thereof. The cannabidiol powder in the spinning solution can be evenly dispersed in the alginate solution, so that the spinning solution of the present invention can be applied to wet spinning to form the alginate fiber comprising cannabidiol. The alginate fiber comprising cannabidiol has anti-oxidative, anti-bacterial, antiinflammatory, and anti-allergic abilities.
    Type: Application
    Filed: October 27, 2022
    Publication date: May 4, 2023
    Inventors: Chen-Lung LIN, Wen-Pin CHIEN
  • Publication number: 20220348956
    Abstract: Provided is a lentivirus packaging system, which comprises: a transfer plasmid comprising a nucleotide sequence of TAR-reserved-chimeric 5? long terminal repeat (LTR); at least one packaging plasmid comprising a nucleotide sequence encoding TAR RNA binding protein, a nucleotide sequence of rev gene, a nucleotide sequence of gag gene, and a nucleotide sequence of pol gene; and an envelope plasmid. Due to the expression of gene of TAR RNA binding protein by the packaging plasmids, the produced lentivirus has higher virus titer and can improve the transduction rate and the gene delivery efficiency during cell transduction. The present invention further provides a method of improving lentivirus production in a host cell, which comprises using the lentivirus packaging system to transfect the host cell. The present invention further provides a cell transduced by the lentivirus and a method of using the cell for treating cancer.
    Type: Application
    Filed: July 16, 2021
    Publication date: November 3, 2022
    Inventors: Wei-Chi LIN, Ssu-Yu CHOU, Yao-Cheng YANG, Chien-Ting LIN, CHEN-LUNG LIN
  • Publication number: 20220119447
    Abstract: The present invention relates to a peptide and use thereof in manufacturing a medicament for treating an inflammatory disease, wherein the peptide comprises an amino acid sequence of SEQ ID NO: 1 and the medicament comprises an effective amount of the peptide and a pharmaceutically acceptable carrier. Also provided is the use of the peptide for the manufacture of a medicament for treating pain, wherein the medicament comprises an effective amount of the peptide and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: October 18, 2019
    Publication date: April 21, 2022
    Inventor: CHEN-LUNG LIN
  • Patent number: 11254706
    Abstract: Hepatitis C virus (HCV) infection is a leading cause for liver cirrhosis and hepatocellular carcinoma worldwide2. Current therapeutic regimens are usually poorly tolerated and only effective in a proportion of infected individuals. We discovered a peptide with sequence of DEAQETAVSSHEQD (SEQ ID NO: 1), a fragment of rabbit ?1-antiproteinase F, and its derivatives DEAQETAVSSHEQ (SEQ ID NO: 2) and QETAVSSHEQD (SEQ ID NO: 3), significantly inhibit serum-borne HCV replication in hADSC and human hepatocytes.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: February 22, 2022
    Assignee: Inno Bio-Drug Development Limited
    Inventor: Chen-Lung Lin
  • Patent number: 10538070
    Abstract: A non-polyvinylchloride (non-PVC) surface covering is provided. The non-PVC surface covering includes a bottom material layer. A middle layer is disposed on the bottom material layer, wherein the middle layer includes a middle material layer. A transparent abrasion-resistant layer is disposed on the middle layer, wherein the transparent abrasion-resistant layer includes a polyolefin of 40˜94.95 wt %, a polyolefin elastomer (POE) or a polyolefin plastomer (POP) of 5˜50 wt %, and a processing agent of 0.05˜10 wt %.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: January 21, 2020
    Assignee: HANDSOME PLASTICS CO., LTD.
    Inventors: Chen-Lung Lin, Henn-Sheng Hsia, Wan-Hui Lin
  • Patent number: 10273461
    Abstract: Hepatitis C virus replication at extrahepatic sites has been suggested; however, complete viral replication has only been confirmed in hepatocytes. Here we show that human adipogenic DLK-1+ stem cells (hADSC) freshly isolated from HCV-infected individuals contained viral transcripts, replication intermediates and viral antigens in vivo, and viral transcripts increased in supernatants upon prolonged ex vivo culture. Furthermore, naive hADSC isolated from HCV (?) individuals support complete replication of clinical isolates in vitro, and the infection is donor-nonspecific for cells and cross-genotypic for viruses. Viral infection/replication is mediated through CD81, LDL-R, SR-B1, EGFR, Apolipoprotein E, occludin, claudin-1, NPC1L1 and diacylglycerol acetyltransferase-1, and can be inhibited by anti-viral drugs.
    Type: Grant
    Filed: January 7, 2015
    Date of Patent: April 30, 2019
    Assignee: FRONTIER BIO-DRUG DEVELOPMENT LIMITED
    Inventor: Chen-Lung Lin
  • Patent number: 10130676
    Abstract: The present invention provides a method for treating or ameliorating cerebrovascular diseases in a subject by using peptides isolated from extracts from rabbit skin inflamed by vaccinia virus. The present invention also provides a peptide comprising an amino acid sequence having at least 70% identity to SEQ ID NO: 1, or variants, mutants, derivatives, or fragments thereof.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: November 20, 2018
    Assignee: Prime Bio-Drug Development Limited
    Inventor: Chen-Lung Lin
  • Publication number: 20180281368
    Abstract: A non-polyvinylchloride (non-PVC) surface covering is provided. The non-PVC surface covering includes a bottom material layer. A middle layer is disposed on the bottom material layer, wherein the middle layer includes a middle material layer. A transparent abrasion-resistant layer is disposed on the middle layer, wherein the transparent abrasion-resistant layer includes a polyolefin of 40˜94.95 wt %, a polyolefin elastomer (POE) or a polyolefin plastomer (POP) of 5˜50 wt %, and a processing agent of 0.05˜10 wt %.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 4, 2018
    Inventors: Chen-Lung LIN, Henn-Sheng HSIA, Wan-Hui LIN
  • Publication number: 20180134751
    Abstract: The present invention provides a peptide with sequence of DEAQETAVSSHEQD, a fragment of rabbit-?1 antiproteinase F, and its derivatives DEAQETAVSSHEQ and QETACSSHEQD, which significantly inhibit serum-borne HCV replication in hADSC and human hepatocytes.
    Type: Application
    Filed: April 16, 2015
    Publication date: May 17, 2018
    Inventor: Chen-Lung Lin
  • Publication number: 20180125923
    Abstract: The present invention provides a method for treating or ameliorating cerebrovascular diseases in a subject by using peptides isolated from extracts from rabbit skin inflamed by vaccinia virus. The present invention also provides a peptide comprising an amino acid sequence having at least 70% identity to SEQ ID NO: 1, or variants, mutants, derivatives, or fragments thereof.
    Type: Application
    Filed: April 16, 2015
    Publication date: May 10, 2018
    Inventor: Chen-Lung Lin
  • Publication number: 20180023058
    Abstract: Hepatitis C virus replication at extrahepatic sites has been suggested; however, complete viral replication has only been confirmed in hepatocytes. Here we show that human adipogenic DLK-1+ stem cells (hADSC) freshly isolated from HCV-infected individuals contained viral transcripts, replication intermediates and viral antigens in vivo, and viral transcripts increased in supernatants upon prolonged ex vivo culture. Furthermore, naive hADSC isolated from HCV (?) individuals support complete replication of clinical isolates in vitro, and the infection is donor-nonspecific for cells and cross-genotypic for viruses. Viral infection/replication is mediated through CD81, LDL-R, SR-B1, EGFR, Apolipoprotein E, occludin, claudin-1, NPC1L1 and diacylglycerol acetyltransferase-1, and can be inhibited by anti-viral drugs.
    Type: Application
    Filed: January 7, 2015
    Publication date: January 25, 2018
    Inventor: Chen-Lung Lin
  • Patent number: 9511568
    Abstract: In a non-PVC tile, a bottom material layer, a printing layer and a transparent wear-resistant layer are disposed from bottom to top. The printing layer includes an inorganic filling material of 55˜90 percentage weight (wt %). The coefficient of thermal expansion of the bottom material layer and the transparent wear-resistant layer are larger than that of the printing layer. When the bottom material layer, the printing layer and the transparent wear-resistant layer are heated and then cooled, the bottom material layer and the transparent wear-resistant layer symmetrically contract with the printing layer being a center.
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: December 6, 2016
    Assignee: M.J. INTERNATIONAL FLOORING AND INTERIOR PRODUCTS INC.
    Inventors: Chen-Lung Lin, Henn-Sheng Hsia, Shih-An Lin, Pen-Yuan Chen
  • Publication number: 20160263871
    Abstract: In a non-PVC tile, a bottom material layer, a printing layer and a transparent wear-resistant layer are disposed from bottom to top. The printing layer includes an inorganic filling material of 55˜90 percentage weight (wt %). The coefficient of thermal expansion of the bottom material layer and the transparent wear-resistant layer are larger than that of the printing layer. When the bottom material layer, the printing layer and the transparent wear-resistant layer are heated and then cooled, the bottom material layer and the transparent wear-resistant layer symmetrically contract with the printing layer being a center.
    Type: Application
    Filed: July 1, 2015
    Publication date: September 15, 2016
    Inventors: Chen-Lung LIN, Henn-Sheng HSIA, Shih-An LIN, Pen-Yuan CHEN
  • Patent number: 9371233
    Abstract: A polyamide-imide represented by the following formula is provided. A graphite film prepared by performing a thermal treatment process on the polyamide-imide represented by the above-mentioned formula is also provided. In the thermal treatment process, the temperature range of the thermal treatment process ranges from 25° C. to 2,900° C.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: June 21, 2016
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chen-Lung Lin, Yen-Chun Liu, Hui-Wen Chang, Kuo-Chan Chiou, Hsien-Lin Hu
  • Patent number: 9308706
    Abstract: The present disclosure relates to a graphite oxide-containing resin formulation, including: 15-80 parts by weight of a polyamideimide precursor, 0.01-10 parts by weight of a graphite oxide as a dispersant, 10-400 parts by weight of an inorganic powder, and 20-350 parts by weight of a solvent.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: April 12, 2016
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Chan Chiou, Lu-Shih Liao, Chen-Lung Lin
  • Publication number: 20150166347
    Abstract: A polyamide-imide represented by the following formula is provided. A graphite film prepared by performing a thermal treatment process on the polyamide-imide represented by the above-mentioned formula is also provided. In the thermal treatment process, the temperature range of the thermal treatment process ranges from 25° C. to 2,900° C.
    Type: Application
    Filed: September 12, 2014
    Publication date: June 18, 2015
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chen-Lung LIN, Yen-Chun LIU, Hui-Wen CHANG, Kuo-Chan CHIOU, Hsien-Lin HU
  • Patent number: 8857600
    Abstract: A conveying apparatus used for conveying an object is provided. The conveying apparatus includes a first conveying unit, a second conveying unit, and a supporting unit. An object leans against the first conveying unit and the second conveying unit and moves from the first conveying unit toward the second conveying unit along a conveying path. The supporting unit is configured between the first conveying unit and the second conveying unit to support and guide the object.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: October 14, 2014
    Assignee: Industrial Technology Research Institute
    Inventors: Guo-Shing Huang, Hsin-Yun Hsu, Ching-Chih Wei, Chen-Lung Lin
  • Publication number: 20140178823
    Abstract: A photosensitive polyimide and negative type photo-resist composition containing the same are provided. The photosensitive polyimide is represented by formula (I): wherein X1 and X3 are the same or different organic functional groups having four covalent bonds; X2 and X4 are the same or different organic functional groups having two covalent bonds, and X2 contains functional groups of OH or COOH and any one selected from the functional groups below: wherein R is H or CH3, p and q are integers of 1 to 20, and m and n in formula (I) are numbers of repeat units.
    Type: Application
    Filed: June 3, 2013
    Publication date: June 26, 2014
    Inventors: Chen-Lung LIN, Fu-Shun HSU, Kuo-Chan CHIOU
  • Publication number: 20140144753
    Abstract: A conveying apparatus used for conveying an object is provided. The conveying apparatus includes a first conveying unit, a second conveying unit, and a supporting unit. An object leans against the first conveying unit and the second conveying unit and moves from the first conveying unit toward the second conveying unit along a conveying path. The supporting unit is configured between the first conveying unit and the second conveying unit to support and guide the object.
    Type: Application
    Filed: April 8, 2013
    Publication date: May 29, 2014
    Applicant: Industrial Technology Research Institute
    Inventors: Guo-Shing Huang, Hsin-Yun Hsu, Ching-Chih Wei, Chen-Lung Lin