Abstract: Uses of pharmaceutical compositions comprising berberine for treatment of dermatologic toxicities and other skin disorders.

Abstract: Uses of pharmaceutical compositions comprising berberine for treatment of dermatologic toxicities and other skin disorders.

Abstract: Pharmaceutical compositions comprising berberine for treatment of skin disorders and methods of use thereof.

Abstract: Pharmaceutical compositions comprising berberine for treatment of skin disorders and methods of use thereof.

Abstract: A self-locking nut assembly includes a nut, and a washer connected with the nut. The nut has a screw bore and a protruding conical ring. The washer has a central portion provided with a conical hole which includes a limit section and an annular tapered section. The conical ring is extended through the conical hole. The conical ring of the nut has a distal portion provided with an annular opening which is enlarged and expanded outward to form a protruding flange. The protruding flange is limited by the limit section of the conical hole. Thus, a determined clearance is defined between the conical ring of the nut and the conical hole of the washer, so that the nut and the washer have determined axial and radial gaps, and the washer can be rotated freely.

Abstract: Hexagonal washers are formed by the following steps: at least two through holes are provided in the middle of a belt of material, which are also used for positioning and advancing the belt; a first residual slot is formed between every two adjacent through holes; a second residual slot and a third residual slot are formed at the two sides of every first residual slot, thereby forming a hexagonal ring around each through hole; six wedge planes are forged around the bottom surface of each ring, and at least a V-shaped groove or a ridge is forged on the top surface of each ring; a larger through hole as the inner hole of a washer is produced at the center of each ring; the major shape of each washers is then formed without separating the washers from the belt; and the washers are fine-tuned to obtain the precise form factor and dimension before they separated from the belt.

Abstract: A novel plastic fastening device is provided herein, which mainly contains a bolt, a nut, and at least a washer. On the surface of the washer that interfaces with the object being fastened, a number of small wedges are arranged radially with equal spacing therebetween. Inside at least one of the small wedges, a plate is embedded vertically with a saw-toothed edge facing towards the object being fastened. When the bolt and nut are screwed together and the small wedges on the washer are pressed against the object, the pointed edges of the small wedges are deformed, and the saw teeth of the embedded plate is exposed and driven into the object for a superior fastening effect.

Abstract: A bolt and washer assembly includes a washer, and a bolt including a threaded rod extended through the washer and a bolt head mounted on the threaded rod. The bolt head of the bolt has a top formed with a protruding ring and a circular recessed portion which is encompassed by the protruding ring and provided with at least two ratchet teeth. Thus, the bolt head has a peripheral wall having a smooth cone-shaped configuration so that the bolt head is operated by a special tool, and a person cannot use a common tool to hold the bolt head to rotate the bolt so as to prevent the bolt from being unscrewed from the workpiece so that the bolt and washer assembly has a burglarproof function.

Abstract: Circular washers are formed by the following steps: at least two through holes are provided in the middle of a belt of material, which are also used for positioning and advancing the belt; a residual slot is formed between every two adjacent through holes, thereby forming a circular ring around each through hole; six wedge planes are forged around the bottom surface of each ring, and at least a V-shaped groove or a ridge is forged on the top surface of each ring; a larger through hole as the inner hole of a washer is produced at the center of each ring; the major shape of each washers is then formed without separating the washers from the belt; and the washers are fined-tuned to obtain the precise form factor and dimension before they separated from the belt.

Abstract: Hexagonal washers are formed by the following steps: at least two through holes are provided in the middle of a belt of material, which are also used for positioning and advancing the belt; a first residual slot is formed between every two adjacent through holes; a second residual slot and a third residual slot are formed at the two sides of every first residual slot, thereby forming a hexagonal ring around each through hole; six wedge planes are forged around the bottom surface of each ring, and at least a V-shaped groove or a ridge is forged on the top surface of each ring; a larger through hole as the inner hole of a washer is produced at the center of each ring; the major shape of each washers is then formed without separating the washers from the belt; and the washers are fine-tuned to obtain the precise form factor and dimension before they separated from the belt.

Abstract: Circular washers are formed by the following steps: at least two through holes are provided in the middle of a belt of material, which are also used for positioning and advancing the belt; a residual slot is formed between every two adjacent through holes, thereby forming a circular ring around each through hole; six wedge planes are forged around the bottom surface of each ring, and at least a V-shaped groove or a ridge is forged on the top surface of each ring; a larger through hole as the inner hole of a washer is produced at the center of each ring; the major shape of each washers is then formed without separating the washers from the belt; and the washers are fine-tuned to obtain the precise form factor and dimension before they separated from the belt.

Abstract: A novel plastic fastening device is provided herein, which mainly contains a bolt, a nut, and at least a washer. On the surface of the washer that interfaces with the object being fastened, a number of small wedges are arranged radially with equal spacing therebetween. Inside at least one of the small wedges, a plate is embedded vertically with a saw-toothed edge facing towards the object being fastened. When the bolt and nut are screwed together and the small wedges on the washer are pressed against the object, the pointed edges of the small wedges are deformed, and the saw teeth of the embedded plate is exposed and driven into the object for a superior fastening effect.

Abstract: A loose-screw bolt is disclosed. The screw bolt comprises a pad, a bolt and a nut, wherein the pad is a flat surface and the flat surface is provided with at least a V-shaped slot arranged radially. The V-shaped slot includes a sloping face and a vertical wall, and the sloping face is along the tightening direction of the bolt. When the screw nut rotates counter-clockwise, the frictional force of the pad at the sloping face and the surface of a work piece will increase with respect to the anti-clockwise rotation of the screw nut.