Patents by Inventor Chen-Wen Yao

Chen-Wen Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10221152
    Abstract: The present invention relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against influenza virus. The present invention also relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against drug-resistant influenza virus strains. The present invention is further related to a method for treating influenza in a subject, comprising administering to said subject an effective amount of mycophenolate mofetil or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: March 5, 2019
    Assignee: GIANT FORCE TECHNOLOGY CORPORATION
    Inventors: An-Rong Lee, Chi-Hong Chu, Wen-Liang Chang, Chen-Wen Yao, Wen-Hsin Huang, Li-Heng Pao
  • Publication number: 20160052905
    Abstract: The present invention relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against influenza virus. The present invention also relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against drug-resistant influenza virus strains. The present invention is further related to a method for treating influenza in a subject, comprising administering to said subject an effective amount of mycophenolate mofetil or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 22, 2013
    Publication date: February 25, 2016
    Inventors: An-Rong LEE, Chi-Hong CHU, Wen-Liang CHANG, Chen-Wen YAO, Wen-Hsin HUANG, Li-Heng PAO
  • Publication number: 20130101998
    Abstract: The present invention provides biomarkers for detecting kidney disease, selected from the oligonucleotide sequence, complementary sequence or derivatives, amino acid sequence or derivatives, fragment, variants, antibody of annexin A2 or S100A6 or combinations thereof. Moreover, the present invention also provides an assay kit and a method for kidney disease detecting, practically for the kidney disease resulting from acute tubular necrosis.
    Type: Application
    Filed: September 14, 2012
    Publication date: April 25, 2013
    Applicant: National Defense Medical Center
    Inventors: Ann Chen, Shuk-Man Ka, Chao-Wen Cheng, Jenn-Han Chen, Chen-Wen Yao
  • Patent number: 8414938
    Abstract: Disclosed are an Schisandrae fructus extract for inhibition or prevention of influenza and its application, wherein the Schisandrae fructus extract is obtained by water, methanol, or ethanol extraction process and the extract comprises compounds such as schisandrone, benzoylgomisin P, wulignan A1, epigomisin O, epiwulignan A1, and tigloylgomisin P. The extracts and purified compounds of Schisandrae fructus has anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities, therefore the extracts and the purified compounds of Schisandrae fructus can be applied as an inhitibory agent of a pharmaceutical composition for treatment or prevention agent for influenza infection.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: April 9, 2013
    Assignee: National Defense Medical Center
    Inventors: Wen-Liang Chang, Chen-Wen Yao, Chi-Hong Chu, An-Rong Lee, Ann Chen, Wen-Hsin Huang, Kuo-Yuan Hwa, Chiao-Ying Chien, Chien-Yi Pai
  • Patent number: 8329410
    Abstract: The present invention provides biomarkers for detecting kidney disease, selected from the oligonucleotide sequence, complementary sequence or derivatives, amino acid sequence or derivatives, fragment, variants, antibody of annexin A2 or S100A6 or combinations thereof. Moreover, the present invention also provides an assay kit and a method for kidney disease detecting, practically for the kidney disease resulting from acute tubular necrosis.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: December 11, 2012
    Assignee: National Defense Medical Center
    Inventors: Ann Chen, Shuk-Man Ka, Chao-Wen Cheng, Jenn-Han Chen, Chen-Wen Yao
  • Publication number: 20120189719
    Abstract: Disclosed are an Schisandrae fructus extract for inhibition or prevention of influenza and its application, wherein the Schisandrae fructus extract is obtained by water, methanol, or ethanol extraction process and the extract comprises compounds such as schisandrone, benzoylgomisin P, wulignan A1, epigomisin O, epiwulignan A1, and tigloylgomisin P. The extracts and purified compounds of Schisandrae fructus has anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities, therefore the extracts and the purified compounds of Schisandrae fructus can be applied as an inhitibory agent of a pharmaceutical composition for treatment or prevention agent for influenza infection.
    Type: Application
    Filed: November 17, 2011
    Publication date: July 26, 2012
    Applicant: NATIONAL DEFENSE MEDICAL CENTER
    Inventors: WEN-LIANG CHANG, CHEN-WEN YAO, CHI-HONG CHU, AN-RONG LEE, ANN CHEN, WEN-HSIN HUANG, KUO-YUAN HWA, CHIAO-YING CHIEN, CHIEN-YI PAI
  • Publication number: 20120101157
    Abstract: Disclosed are 4,5-diamino-3-halo-2-hydroxybenzoic acid derivatives and manufactures thereof. The 4,5-diamino-3-halo-2-hydroxybenzoic acid derivatives are presented by formula (I): wherein R1 group is H, CH3, or C2H5; R2 group is H, or Br; R3 group is CH3, or C3H7; and R4 group is H, or C(?NH)—NH2. 4,5-diamino-3-halo-2-hydroxybenzoic acid derivatives provided here were non-toxic to MDCK cells, particularly compounds 6a, 6b, 6c, 6e, 6f, 7a, 7b and 8 had better anti-H1N1 activity. In the future, these compounds can be used to focus on viral neuraminidases as targets to develop effective anti-influenza drugs.
    Type: Application
    Filed: October 24, 2011
    Publication date: April 26, 2012
    Applicant: NATIONAL DEFENSE MEDICAL CENTER
    Inventors: AN-RONG LEE, WEN-HSIN HUANG, CHI-HONG CHU, WEN-LIANG CHANG, CHEN-WEN YAO, I-LING CHEN
  • Publication number: 20100081142
    Abstract: The present invention provides biomarkers for detecting kidney disease, selected from the oligonucleotide sequence, complementary sequence or derivatives, amino acid sequence or derivatives, fragment, variants, antibody of annexin A2 or S100A6 or combinations thereof. Moreover, the present invention also provides an assay kit and a method for kidney disease detecting, practically for the kidney disease resulting from acute tubular necrosis.
    Type: Application
    Filed: August 12, 2009
    Publication date: April 1, 2010
    Applicant: National Defense Medical Center
    Inventors: Ann Chen, Shuk-Man Ka, Chao-Wen Cheng, Jenn-Han Chen, Chen-Wen Yao
  • Publication number: 20080152735
    Abstract: The invention provides a herbal extract having anti-influenza virus activity, by extracting Sophora flavescens Ait, Thesium chinense Turcz, licorice, or mixture thereof with solvent.
    Type: Application
    Filed: December 21, 2007
    Publication date: June 26, 2008
    Applicant: NATIONAL DEFENSE MEDICAL CENTER
    Inventors: Wen-Liang Chang, Chen-Wen Yao, Ann Chen, Chung-Yang Yen, Li-Shian Shi, Jenn-Han Chen, Ching-Len Liao, Kuo-Yuan Hwa, An-Rong Lee, Po-Huang Liang
  • Publication number: 20070254290
    Abstract: This invention discloses a method for diagnosing Crescentic glomerulonephritis (CRGN) using at least a sample from a patient. The method is to find a least one biomarker for diagnosing Crescentic glomerulonephritis. The genetic performance of Sparc, Lcn2 and/or Spp1 can be used as biomarkers.
    Type: Application
    Filed: November 8, 2006
    Publication date: November 1, 2007
    Inventors: Chung-Yang Yen, Ann Chen, Ching-Len Liao, Jenn-Han Chen, Wen-Liang Chang, Chen-Wen Yao, Kuo-Yuan Hwa
  • Publication number: 20070154897
    Abstract: The present invention provides biomarkers for detecting kidney disease, selected from the oligonucleotide sequence, complementary sequence or derivatives, amino acid sequence or derivatives, fragment, variants, antibody of annexin A2 or S100A6 or combinations thereof. Moreover, the present invention also provides an assay kit and a method for kidney disease detecting, practically for the kidney disease resulting from acute tubular necrosis.
    Type: Application
    Filed: April 20, 2006
    Publication date: July 5, 2007
    Applicant: National Defense Medical Center
    Inventors: Chung-Yang Yen, Ching-Len Liao, Jenn-Han Chen, Wen-Liang Chang, Ann Chen, Kuo-Yuan Hwa, Chen-Wen Yao, Chao-Wen Cheng, Shun-Min Yang