Patents by Inventor Chen-Yun CHEN

Chen-Yun CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microrna let-7 and transforming growth factor beta receptor III axis as target for cardiac injuries
    Patent number: 11246883
    Abstract: Methods for ameliorating cardiac is juries such as myocardial infarction by either enhancing the activity of a let-7 microRNA or inhibiting the activity of transformation growth factor beta receptor III (T GFBR3). Also provided herein are assay methods for detecting the level of TGFBR3, the level of a let-7 microRNA, or both in a biological sample.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: February 15, 2022
    Assignee: Academia Sinica
    Inventors: Patrick C. H. Hsieh, Chen-Yun Chen, Yu-Che Cheng
  • MICRORNA LET-7 AND TRANSFORMING GROWTH FACTOR BETA RECEPTOR III AXIS AS TARGET FOR CARDIAC INJURIES
    Publication number: 20190275070
    Abstract: Methods for ameliorating cardiac is juries such as myocardial infarction by either enhancing the activity of a let-7 microRNA or inhibiting the activity of transformation growth factor beta receptor III (T GFBR3). Also provided herein are assay methods for detecting the level of TGFBR3, the level of a let-7 microRNA, or both in a biological sample.
    Type: Application
    Filed: September 29, 2017
    Publication date: September 12, 2019
    Applicant: Academia Sinica
    Inventors: Patrick C.H. Hsieh, Chen-Yun Chen, Yu-Che Cheng
  • METHOD AND KIT FOR MAKING DIAGNOSIS OF MYOCARDIAL INFARCTION
    Publication number: 20180298442
    Abstract: Disclosed herein are a method and a kit for making a diagnosis as to whether a subject suffers from myocardial infarction (MI). The method and the kit can accurately and efficiently identify the MI patient through detecting the circulating let-7a and let-7f, both of which are highly expressed in healthy subject, and downregulated in MI patient. According to the present method and kit, the MI patient is capable of receiving a proper treatment in time.
    Type: Application
    Filed: September 30, 2016
    Publication date: October 18, 2018
    Inventors: Patrick C.H. HSIEH, Chen-Yun CHEN