Abstract: Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.

Abstract: According to one embodiment, a measuring apparatus includes a weighing scale, an imaging unit, an identification unit, and an output unit. The weighing scale is configured to measure a weight of merchandise placed in a space for measurement. The imaging unit is configured to image the space for measurement. The identification unit is configured to identify the merchandise placed in the space for measurement, based on a feature of the merchandise shown in an image captured by the imaging unit. The output unit is configured to output predetermined data through which merchandise placed in the space for measurement and a sales price of the merchandise can be specified respectively, based on the weight measured by the weighing scale and an identification result obtained by the identification unit.

Abstract: Compounds within the scope of the present invention have a Formula 1 or a salt or produg thereof, where ring A is selected from cycloaliphatic; ring B is aryl; R1 is selected from (C1-C10)alkyl, (C3-C10)cycloalkyl, halo, aryl, and heteroaryl; and R2 and R3 are independently selected from hydrogen and (C1-C6)alkyl. Disclosed compounds may have an IRAK4 IC50 of from 0.003 ?M to 3.7 M; a TAK1 IC50 of from 0.008 ?M to 132 M; and/or an IRAK4/TAK1 selectivity of from 1 to 450. Particular compounds may have an IRAK4/TAK1 selectivity of from 100 to 500. Disclosed compositions may be formulated as pharmaceutical compositions. A method for using the compounds and/or compositions also are disclosed. The method may comprise administering to a subject an effective amount of a compound within the scope of the present invention, particularly to selectively inhibit IRAK 1 and/or IRAK4 over TAK1.

Abstract: Disclosed is a sensor with compensation circuit for compensating offset by use of a switching circuit. The sensor has two operation modes for generating two output voltages, respectively. Offset is compensated by adding the two output voltages, and magnitude of the offset is calculated by subtracting the two output voltages. A noise threshold is set for checking if the circuit is affected by interference. When the circuit is affected by interference, the adding result of the two output voltages will be larger than the noise threshold, the output data will be hold and not updated, then a reminding signal will be issued to show that the circuit is affected by interference, and the output data flickers on a display unit when the adding result of the two output voltages is larger than the noise threshold for showing the circuit is affected by interference.

Abstract: A NEMS device structure and a method for forming the same are provided. The NEMS device structure includes a first dielectric layer formed over a substrate, and a first conductive layer formed in the first dielectric layer. The NEMS device structure includes a second dielectric layer formed over the first dielectric layer, and a first supporting electrode a second supporting electrode and a beam structure formed in the second dielectric layer. The beam structure is formed between the first supporting electrode and the second supporting electrode, and the beam structure has a T-shaped structure. The NEMS device structure includes a first through hole formed between the first supporting electrode and the beam structure, and a second through hole formed between the second supporting electrode and the beam structure.

Abstract: The present disclosure discloses a radiotherapeutic device. The radiotherapeutic device comprises a gantry, at least two therapeutic heads, a first detector and a slide driving unit. The slide driving unit comprises a sliding guide rail, a driving apparatus and a movable block. The first detector is fixed on the movable block and is driven by the movable block via the driving apparatus to slide along the sliding guide rail to different positions to receive radiation beams emitted by therapeutic heads.

Abstract: A method for manufacturing a radio frequency (RF) applicator which includes covering a ceramic insert with a coating, wherein the ceramic insert has dimensions that substantially match an internal volume of an open-ended, hollow waveguide, and wherein the ceramic insert has a recess therein configured to accept a radio frequency emitter, heating the waveguide to a temperature that is above a melting point of the coating, placing the coated ceramic insert into the internal volume of the heated waveguide, wherein the internal volume is completely filled except for the recess, and cooling the waveguide, ceramic insert, and coating to a temperature below the melting point of the coating so that the coating solidifies and fills gaps between facing surfaces of the insert and the waveguide.

Abstract: A computer-implemented method for recommending a monitoring interval in provided. A non-limiting example of the computer-implemented method includes receiving, by a processor, monitoring data at an initial monitoring interval and calculating, by the processor, a set of aggregation data from the monitoring data including a first subset of aggregation data at a first interval of the initial monitoring interval. The method calculates, by the processor, a first density score for the first subset of aggregation data and a first indicator score for the first subset of aggregation data and provides, by the processor, the first interval as a recommended interval when the first density score does not exceed a density threshold and the first indicator threshold does not exceed an indicator threshold.

Abstract: A method and apparatus for enabling repetitive transmissions for low latency systems is disclosed. For example, a base station may determine whether an uplink coverage parameter for a UE communicating with the network entity on an uplink communication channel satisfies an uplink coverage threshold, and transmit an activation message for repetition-based uplink communications to the UE based on a determination that the uplink coverage parameter for the UE communicating with the network entity on the uplink communication channel satisfies the uplink coverage threshold. Further, a UE may receive an activation message for repetition-based uplink communications from a network entity, and perform repetitive transmissions on the uplink communication channel for the duration indicated by the one or more transmission parameters in the activation message, the repetitive transmissions being configured based on the uplink sTTI pattern.

Abstract: A substrate structure with high reflectance includes a base material, a patterned circuit layer, an insulating layer and a metal reflecting layer. The base material includes a first surface and a second surface opposite to the first surface. The patterned circuit layer is disposed on the first surface. The insulating layer covers the patterned circuit layer and a part of the first surface exposed by the patterned circuit layer. The metal reflecting layer covers the insulating layer, and a reflectance of the metal reflecting layer is substantially greater than or equal to 85%. A manufacturing method of a substrate structure with high reflectance is also provided.

Abstract: Disclosed are systems and methods for manufacturing energy relays for energy directing systems. Methods and devices are disclosed for forming random and non-random patterns of energy relay materials with energy localization properties. Methods and devices are disclosed for forming energy relays of different shapes.

Abstract: Provided is an information transmission method, apparatus and system. The information transmission method includes: obtaining, by a first communication node, a control channel description list which includes description information of N control channels, where N is a positive integer and the description information of each of the control channels includes one or more of: control channel configuration information, reference signal configuration information, link resource configuration information, operating bandwidth configuration information, puncturing configuration information, frequency hopping configuration formation, transmission time interval length configuration information, power control configuration information and beam configuration information; and sending, by the first communication node, the control channel description list to a second communication node.

Abstract: The invention discloses a calculation method for dynamic fluid loss of acid-etched fracture considering wormhole propagation, which is applied to pad acid fracturing process, comprising the following steps: Step 1: dividing the construction time T of injecting acid fluid into artificial fracture into m time nodes at equal intervals, then the time step ?t=T/m and tn=n?t, where, n=0, 1, 2, 3, . . . , m, and to is the initial time; Step 2: calculating the fluid loss velocity vl(0) in the fracture at t0; Step 3: calculating the flowing pressure distribution P(n) in the fracture at tn; Step 4: calculating the width wa(n) of acid-etched fracture at tn; Step 5: calculating the wormhole propagation and the fluid loss velocity vl(n) at tn; Step 6: substituting the fluid loss velocity vl(n) into Step 3, and repeating Step 3 to Step 6 in turn until the end of acid fluid injection.

Abstract: A system for training and deploying an artificial conversational entity using an artificial intelligence (AI) based communications system is disclosed. The system may comprise a memory storing machine readable instructions. The system may also comprise a processor to execute the machine readable instructions to receive a request via an artificial conversational entity. The processor may also transmit a response to the request based on a dialog tree generated from at least a model-based action generator and a memory-based action generator. The processor may further provide a training option to a user in the event the response is suboptimal. The processor may additionally receive a selection from the user via the training option. The selection may be associated with an optimal response.

Abstract: Compositions and methods relating to bacterial ribosomes selected to increase the incorporation of at least one glycosylated amino acid into a protein versus a wild-type bacterial ribosome. Selection embodiments include growing bacteria in the presence of a puromycin derivative, wherein a surviving clone has a ribosome that incorporates at least one glycosylated amino acid into a protein.

Abstract: A method for replying with an acknowledgement frame includes: calculating, by an access point (AP), sending duration of a physical layer service data unit (PSDU) in a to-be-sent downlink physical layer protocol data unit (downlink PPDU) based on a format and a sending rate that are of the downlink PPDU and based on only that a length of each block acknowledgement bitmap field in a block acknowledgement frame in the downlink PPDU is a maximum quantity of bytes that is of each respective block acknowledgement bitmap field of the plurality of stations (STAs), to generate an legacy signal field of a second preamble; and generating, by the AP, the block acknowledgement frame, where each STA information subfield in a block acknowledgement information field of the block acknowledgement frame includes an association identifier traffic identifier field, a block acknowledgement starting sequence control field, and a block acknowledgement bitmap field.

Abstract: A physical vapor deposition system includes a chamber, three target supports to targets, a movable shield positioned having an opening therethrough, a workpiece support to hold a workpiece in the chamber, a gas supply to deliver nitrogen gas and an inert gas to the chamber, a power source, and a controller. The controller is configured to move the shield to position the opening adjacent each target in turn, and at each target cause the power source to apply power sufficient to ignite a plasma in the chamber to cause deposition of a buffer layer, a device layer of a first material that is a metal nitride suitable for use as a superconductor at temperatures above 8° K on the buffer layer, and a capping layer, respectively.

Abstract: A radiation resistant high-entropy alloy is provided, having an FCC structure, defined by general formula of FeCoNiVMoTixCry, where 0.05?x?0.2, 0.05?y?0.3, x and y are molar ratios. The radiation resistant high-entropy alloy has excellent irradiation resistance and is subject to radiation hardening saturation at high temperature (600° C.) in a condition of a high dose (1-3×1016 ions/cm2) of helium ion irradiation. A lattice constant of the high-entropy alloy decreases abnormally after irradiation. The high-entropy alloy has a radiation resistance far higher than that of a conventional alloy and has an excellent plasticity and specific strength. In an as-cast condition and at room temperature, a tensile break strength of the high-entropy alloy is higher than 580 MPa, an engineering strain (a tensile elongation) of the high-entropy alloy is greater than 30%.

Abstract: The present disclosure discloses a video decoding method, including: parsing a received bitstream to obtain prediction information of a CU; obtaining a target transform mode of a residual TU; parsing the received bitstream to obtain transform coefficients of the residual TU; applying an inverse quantization to the transform coefficients of the residual TU to obtain dequantized coefficients; applying, based on the target transform mode, an inverse transform to the dequantized coefficients to obtain a residual block of the residual TU; obtaining a prediction block of the CU based on the prediction information; and obtaining a video block based on the residual block and the prediction block; and outputting a video sequence, the video sequence including a video frame that includes the video block.

Abstract: An adjustable supporting frame is disclosed for supporting a display. The adjustable supporting frame mainly comprises a base, a upright, a tilting unit, and a rotating unit, wherein the tilting unit pivotally rotates around an axial line of a connecting shaft, and the rotating unit rotates around a virtual axis, the axial line and the virtual axis intersect with each other.