Abstract: The present disclosure provides an immunoconjugate includes an antibody comprising an antigen-binding fragment that specifically binds to an epitope in mesothelin, N-glycan binding domain and an N-glycan; a linker linking to the N-glycan; and a payload A and a payload B conjugated to the linker, respectively; wherein the payload A and the payload B are the same or different. A pharmaceutical composition comprises the immunoconjugate and a method for treating cancer are also provided in the disclosure.

Abstract: A multifunctional lens assembly includes a functional transparent plate and a layered adhesive body. The functional transparent plate includes spaced apart through holes disposed in an outer peripheral region thereof. Each through hole extends through two opposite surfaces of the outer peripheral region. The layered adhesive body is attached to the functional transparent plate for adhering the functional transparent plate to a face shield of a mobile helmet. The layered adhesive body has a first layer 61 disposed on one of the two opposite surfaces of the outer peripheral region facing toward the face shield, and connection studs respectively extending through the through holes and integrally connecting the first layer.

Abstract: The present invention relates to novel conjugates and pharmaceutical compositions comprising the novel conjugate described herein. The use of the novel conjugate to inhibit the growth of cancer cells and induce antibody production in a subject in need of cancer treatment, with or without an anti-cancer agent, is also provided.

Abstract: A multifunctional lens assembly includes a functional transparent plate and a layered adhesive body. The functional transparent plate includes spaced apart through holes disposed in an outer peripheral region thereof. Each through hole extends through two opposite surfaces of the outer peripheral region. The layered adhesive body is attached to the functional transparent plate for adhering the functional transparent plate to a face shield of a mobile helmet. The layered adhesive body has a first layer 61 disposed on one of the two opposite surfaces of the outer peripheral region facing toward the face shield, and connection studs respectively extending through the through holes and integrally connecting the first layer.