Patents by Inventor Cheng Shaw

Cheng Shaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5728757
    Abstract: The present invention relates to a zinc salt of the formula: ##STR1## and rubber compounds containing such salts.
    Type: Grant
    Filed: August 9, 1996
    Date of Patent: March 17, 1998
    Assignee: The Goodyear Tire & Rubber Company
    Inventors: Richard Michael D'Sidocky, Lawson Gibson Wideman, Bernard Matthew Bezilla, Jr., Cheng Shaw
  • Patent number: 5001238
    Abstract: This invention relates to the process for the preparation of certain 2-phenylalkylthio- and phenylalkylsulfinyl-imidazo[4,5-c]pyridines useful for the treatment of osteoporosis.
    Type: Grant
    Filed: June 19, 1990
    Date of Patent: March 19, 1991
    Assignee: American Home Products Corporation
    Inventors: Chia-Cheng Shaw, Razzak Noureldin, Gregory Gavin
  • Patent number: 4897493
    Abstract: Process for the production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids having useful analgesic and anti-inflammatory activity.
    Type: Grant
    Filed: January 31, 1989
    Date of Patent: January 30, 1990
    Assignee: American Home Products Corporation
    Inventors: Chia-Cheng Shaw, Karel Pelz
  • Patent number: 4824961
    Abstract: Process for the production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids having useful analgesic and anti-inflammatory activity.
    Type: Grant
    Filed: August 27, 1987
    Date of Patent: April 25, 1989
    Assignee: American Home Products Corporation
    Inventors: Chia-Cheng Shaw, Karel Pelz
  • Patent number: 4514333
    Abstract: A process for preparing compounds of the formula ##STR1## in which R is hydrogen or methoxy,R.sub.1 is a hydroxyl group,R.sub.2 is chlorine, bromine, OCOCH.sub.3 or SHET,R.sub.3 is hydrogen or a cleavable carboxy-protecting group preferably selected from loweralkyl, benzyl, benzhydryl, loweralkoxyloweralkyl, loweralkoxybenzyl, phenacyl, trimethylsilyl, 2,2,2-trichloroethyl or pivaloyl,R.sub.4 is hydrogen or a cleavable acyl group, or R.sub.4 NH represents phthalimido, andHET is a five membered aromatic heterocycle containing 1-4 heteroatoms and optionally substituted with loweralkyl,and from which the corresponding 1-oxacephem derivtives can be prepared is described. The novel intermediate compounds of the formula 1 are produced from a penicillin derivative of formula 1 wherein R, R.sub.3 and R.sub.4 are as above described and R.sub.1 and R.sub.2 are both the same halogen, by treatment with a formylating agent in a halogenated hydrocarbon solvent to obtain the corresponding compound in which R.sub.1 and R.
    Type: Grant
    Filed: February 10, 1983
    Date of Patent: April 30, 1985
    Assignee: Queen's University at Kingston
    Inventors: Saul Wolfe, Chia-Cheng Shaw
  • Patent number: 4391975
    Abstract: A process for preparing compounds of the formula ##STR1## in which R is hydrogen or methoxy,R.sub.1 is a hydroxyl group,R.sub.2 is chlorine, bromine, OAc or SHET,R.sub.3 is hydrogen or a cleavable carboxy-protecting group preferably selected from loweralkyl, benzyl, benzhydryl, loweralkoxyloweralkyl, loweralkoxybenzyl, phenacyl, trimethylsilyl, 2,2,2-trichloroethyl or pivaloloxy,R.sub.4 is hydrogen or a cleavable amino-protecting acyl group, or R.sub.4 NH represents phthalimido, andHET is a five or six membered aromatic heterocycle containing 1-4 heteroatoms and optionally substituted with loweralkyl,and from which the corresponding 1-oxacephem derivatives can be prepared is described. The novel intermediate compounds of the formula 1 are produced from a penicillin derivative of formula 1 wherein R, R.sub.3 and R.sub.4 are as above described and R.sub.1 and R.sub.
    Type: Grant
    Filed: March 8, 1982
    Date of Patent: July 5, 1983
    Assignee: Queen's University at Kingston
    Inventors: Saul Wolfe, Chia-Cheng Shaw
  • Patent number: 4327222
    Abstract: 3,4-Diarylisoxazol-5-acetic acids of the formula ##STR1## in which Ar.sup.1 and Ar.sup.2 are the same or different and are selected from phenyl and naphthyl, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are the same or different and are selected from hydrogen, halogen, trifluoromethyl, lower alkyl, and lower alkoxy, and R.sup.5 is selected from hydrogen, lower alkyl, and lower alkoxy. The compounds have anti-inflammatory, analgesic, and anti-pyretic activities and a low order of toxicity, and methods for their preparation and use are also disclosed.
    Type: Grant
    Filed: September 23, 1980
    Date of Patent: April 27, 1982
    Assignee: CDC Life Sciences Inc.
    Inventors: Ronald G. Micetich, Chia-Cheng Shaw, Ram B. Rastogi
  • Patent number: 4172078
    Abstract: Thiazolineazetidinone derivatives of the formulae 1,2, and 3. ##STR1## wherein R is derived from the commonly known carboxamido groups present in penicillins, R.sup.1 is a carboxy protecting group commonly used in penicillin chemistry, and R.sup.2 is Cl, Br, I, CN, lower alkoxy, lower acyloxy, SCN, SCH.sub.3, S-phenyl, S-heteroaryl such as 5-mercaptotetrazole or 2-mercapto-5-methyl-1,3,4-thiadiazole, NO.sub.3, N.sub.3, NH-phenyl, and N(CH.sub.3).sub.2 with the proviso that R.sup.2 in the compounds of formula 1 is limited to Cl, Br, I, and lower acyloxy, and a process for preparing said compounds from 2-(substituted methyl) penicillin sulfoxides followed by treatment with a base.The compounds of formulae 1,2, and 3 are useful as intermediates in the synthesis of cephalosporins.
    Type: Grant
    Filed: December 15, 1977
    Date of Patent: October 23, 1979
    Assignee: Connlab Holdings Limited
    Inventors: Ronald G. Micetich, Chia-Cheng Shaw, Peter K. Wolfert