Patents by Inventor Cheng-Yu Lai

Cheng-Yu Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vault Complexes for Facilitating Biomolecule Delivery
    Publication number: 20110201112
    Abstract: The invention relates to compositions of vault complexes containing recombinant membrane lytic proteins, such as an adenovirus protein VI lytic domain, and methods of using the vault complexes to facilitate delivery and entry of a biomolecule into a cell or subject.
    Type: Application
    Filed: November 19, 2010
    Publication date: August 18, 2011
    Applicant: The Regents of the University of California
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer, Glen R. Nemerow, Cheng-Yu Lai, Christopher M. Wiethoff, Mu Ri Han
  • DEGRADABLE CROSSLINKED AMINATED DEXTRAN MICROSPHERES AND METHODS OF USE
    Publication number: 20110033548
    Abstract: Degradable, crosslinked aminated dextran microspheres are described. The microspheres contain aminated dextran crosslinked with a crosslinking agent having two or more functional groups that are capable of reacting with the primary amine groups of the aminated dextran to form covalent bonds. The degradable, crosslinked aminated dextran microspheres may be useful for temporary therapeutic embolization and drug delivery.
    Type: Application
    Filed: August 3, 2010
    Publication date: February 10, 2011
    Applicant: E.I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Cheng-Yu LAI, Daniela Rodica Radu
  • CAPPED MESOPOROUS SILICATES
    Publication number: 20090252811
    Abstract: The invention provides an article comprising, a mesoporous silicate matrix, such as a particle, having one or more pores; and one or more releasable caps obstructing one or more of the pores. The articles are useful as delivery vehicles for encapsulated agents such as therapeutic agents, polynucleotides, polypeptides and the like.
    Type: Application
    Filed: March 26, 2009
    Publication date: October 8, 2009
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Victor Shang-Yi Lin, Cheng-Yu Lai, Srdija Jeftinija, Dusan M. Jeftinija
  • Capped mesoporous silicates
    Patent number: 7563451
    Abstract: The invention provides an article comprising, a mesoporous silicate matrix, such as a particle, having one or more pores; and one or more releasable caps obstructing one or more of the pores. The articles are useful as delivery vehicles for encapsulated agents such as therapeutic agents, polynucleotides, polypeptides and the like.
    Type: Grant
    Filed: April 22, 2004
    Date of Patent: July 21, 2009
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Victor Shang-Yi Lin, Cheng-Yu Lai, Srdija Jeftinija, Dusan M. Jeftinija
  • Capped mesoporous silicates
    Publication number: 20060154069
    Abstract: The invention provides an article comprising, a mesoporous silicate matrix, such as a particle, having one or more pores; and one or more releasable caps obstructing one or more of the pores. The articles are useful as delivery vehicles for encapsulated agents such as therapeutic agents, polynucleotides, polypeptides and the like.
    Type: Application
    Filed: April 22, 2004
    Publication date: July 13, 2006
    Inventors: Victor Lin, Cheng-Yu Lai, Srdija Jeftinija, Dusan Jeftinija