Abstract: Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.

Abstract: An uncoiling, blanking and forming method includes the steps of: 1) uncoiling a steel coil, wherein a steel strip uncoiled from the steel coil is cleaned and straightened and is fed by a pinch roller to a blanking region; 2) laser blanking, wherein the steel coil enters the blanking region, is cut by a laser cutting head by way of laser blanking to form sheets with a required shape, with waste materials falling down and being conveyed to the outside; 3) outputting the sheets, wherein the sheets pass over a magnetic telescopic belt conveyor, and then carried by means of a manipulator or a robot to a stamping process; 4) stamping forming, wherein the sheets are stamped to form workpieces; and 5) checking, wherein the workpieces are checked and put in storage.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: The present invention relates to a device for collecting body fluids including (a) a fluid receiving part including a fluid receiving space in which an internal low pressure less than an external atmospheric pressure is formed; (b) a fluid collection part including a hollow microstructure connected to form an open system with the fluid receiving space of the fluid receiving part; and (c) a microstructure hollow barrier for blocking the hollow of the microstructure to maintain the internal low pressure formed in the fluid receiving means.

Abstract: An uncoiling and blanking method includes uncoiling a coiled strip, straightening, cutting off the leading end, moving into a looper, moving out of the looper, then cleaning the surface of the coiled strip, and flattening; conveying the coiled strip on a pinch roller to perform laser cutting and blanking, wherein dual static laser cutting heads are used for cutting the coiled strip during the laser cutting, and the cut-away waste materials fall down from the cutting region and are conveyed to the outside; and after the completion of cutting, finally cutting off the obtained sheets from each other, receiving them by a receiving device and conveying same on a conveying belt to a picking up and stacking region to stack the sheets.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver X receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver X receptor. Also provided are the compounds of Formula (I) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, Alzheimer's disease, dermatitis, dyslipidemia, cancer and other diseases or disorders.

Abstract: A metal plate loading/unloading and cutting method and system comprises: a block cart and a sheet cart both of which are arranged on a guide rail; a cutting operation unit arranged at one side of the guide rail; a carrying and stacking robot arranged between the cutting operation unit and the guide rail of the block cart and the sheet cart, a robot external shaft being parallel to the cart guide rail and extending over two fast moving table waiting stations of the cutting operation unit; and a waste material conveying device arranged below the two cutting stations of the cutting operation unit. The present invention can effectively increase material utilization efficiency and further enlarge the range in production and machining, and is especially suitable for providing production of small-batch vehicle models and trial production of new vehicle models.

Abstract: Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.

Abstract: A longitudinal metal plate loading/unloading and cutting method and a system thereof involve two longitudinally moving loading/unloading and cutting operation lines arranged in parallel, each of the operation lines comprising a block loading station, a cutting station, a sheet unloading station, and a carrying and stacking robot arranged between the two operation lines, which are arranged in succession, wherein the two operation lines have block loading directions opposite to each other. The present invention can effectively increase the cutting production rate and yield, and also provide a more reasonable layout of the system.

Abstract: An information processing method and an electronic device are provided. In the method, when an event to be processed is received by an electronic device, a control instruction is generated. The electronic device generates prompting information and controls a display unit of the electronic device to be in a dark state in response to the control instruction. Finally the electronic device outputs the generated prompting information by a first prompting unit in the electronic device.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: A method for combined shearing of a steel plate adopts a combination of unrolling and pendulum shearing with laser cutting, wherein after a steel roll is cut by unrolling and pendulum shearing to obtain sheets having a specified length, a part or all of the sheets are directly conveyed to a stack as finished sheet materials and the other part or all of the sheets are transferred to a laser cutting line by means of lateral material discharge from a unrolling and pendulum cutting line, and are picked up by a loading robot and moved to a laser cutting position to subject to a secondary cutting, so as to finally obtain profiled sheet materials which are picked up by a discharged material handling and stacking robot for an operation of stacking the finished products.

Abstract: Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: The present invention discloses a method of motor vehicle sheet blanking and a system of the same, wherein the blanking method comprises: firstly, nesting for motor vehicle sheet material, and cutting it into group sheets with a shape and size confirmed by the multi length of the sheet; next, designing a backing die depending on scraps to be cut from the group sheet, and hollowing in areas corresponding to blanking openings in the backing die, in which the dimensions of the blanking openings are greater than that of the actual scraps to be cut; then, placing a group sheet onto the backing die; laser cutting the group sheet based on the shape of motor vehicle sheet, the cut scraps dropping through the blanking openings in the backing die onto a scrap conveyor belt underneath; stacking the cut sheets. The present invention can effectively process scraps cut from sheets and improve the blanking efficiency.

Abstract: A device includes a sensor surface and a pair of electrodes. The sensor surface includes a first conductive layer separated from a second conductive layer by an intermediary layer, a magnetization direction of the first conductive layer and a magnetization direction of the second conductive layer having a ground state orientation of approximately 0 degrees. An electrical resistance between the pair of electrodes is determined by a magnetic field proximate the sensor surface.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.