Patents by Inventor Chenghao Ying

Chenghao Ying has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION
    Publication number: 20250018047
    Abstract: Provided are PROTACs comprised of a targeting moiety designed to bind KRAS (G12D) linked to a degrader-directing moiety designed to bind an E3 ubiquitin-ligase. Pharmaceutical compositions comprising the disclosed PROTACs and their use in treating cancer and related conditions are also provided.
    Type: Application
    Filed: November 7, 2022
    Publication date: January 16, 2025
    Inventors: Weiwen Ying, Chenghao Ying, Kevin P. Foley, Lingjie Zhang, Mingkai Wang, Long Ye, Thomas Prince, Wei Yin, Yaya Wang
  • METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION
    Publication number: 20240124460
    Abstract: Provided are compounds of Formula (I) and pharmaceutically acceptable salts and compositions thereof, which are useful for treating cancers and related conditions.
    Type: Application
    Filed: October 12, 2021
    Publication date: April 18, 2024
    Inventors: Weiwen Ying, Kevin P. Foley, Wei Yin, Long Ye, Mingkai Wang, Chenghao Ying, Lingjie Zhang
  • INHIBITORS OF KRAS(G12D)
    Publication number: 20240116950
    Abstract: Provided are small molecule inhibitors of the KRAS(G12D) mutant oncoprotein having the structural formula: and pharmaceutically acceptable salts and compositions thereof, which are useful for treating cancers and related conditions.
    Type: Application
    Filed: September 8, 2023
    Publication date: April 11, 2024
    Inventors: Weiwen Ying, Chenghao Ying, Kevin P. Foley, Zhiyong Wang, Wei Yin, Liang Ma, Guoqiang Wang, Jinhua Li, Yaya Wang, Yan Dai, Thomas Prince
  • METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION
    Publication number: 20230391792
    Abstract: Provided are compounds of Formula: H-L-T and pharmaceutically acceptable salts and compositions thereof, which are useful for treating cancers and related conditions.
    Type: Application
    Filed: October 14, 2021
    Publication date: December 7, 2023
    Inventors: Weiwen Ying, Kevin P. Foley, Long Ye, Mingkai Wang, Chenghao Ying, Wei Yin, Lingjie Zhang
  • METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION
    Publication number: 20230391772
    Abstract: Provided are compounds of Formula (I) and pharmaceutically acceptable salts and compositions thereof, which are useful for treating cancers and related conditions.
    Type: Application
    Filed: October 13, 2021
    Publication date: December 7, 2023
    Inventors: Weiwen Ying, Kevin P. Foley, Mingkai Wang, Chenghao Ying, Long Ye, Wei Yin, Lingjie Zhang
  • INHIBITORS OF KRAS(G12D)
    Publication number: 20230365595
    Abstract: Provided are small molecule inhibitors of the KRAS(G12D) mutant oncoprotein having the structural formula: R00F2C—L—R0 and pharmaceutically acceptable salts and compositions thereof, which are useful for treating cancers and related conditions.
    Type: Application
    Filed: May 12, 2023
    Publication date: November 16, 2023
    Applicant: Ranok Therapeutics (Hangzhou) Co. Ltd.
    Inventors: Weiwen Ying, Kevin P. Foley, Chenghao Ying, Zhiyong Wang, Wei Yin, Yaya Wang, Yan Dai, Thomas Prince