Patents by Inventor Chengjie Li
Chengjie Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250256045Abstract: A nasal droplet delivery device for delivering a stream of fluid droplets to nasal passageways and sinus cavities includes an ejector mechanism with an oscillation actuator that vibrates an aperture plate with a plurality of openings to generate an ejected stream of droplets from fluid with one or more active agents. The ejector mechanism does not elevate in-situ temperatures or forces that decompose or denature the one or more active agents in the fluid.Type: ApplicationFiled: April 28, 2025Publication date: August 14, 2025Inventors: John H. HEBRANK, Christopher W. MAURER, Charles Eric HUNTER, Chengjie LI, Louis Thomas GERMANARIO
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Publication number: 20250235633Abstract: An electronically actuated droplet delivery device includes a housing with an airflow exit at a mouthpiece and an airflow entrance in fluid communication with the airflow exit via an airflow channel. An aperture plate coupled to an electronic actuator energized by a power source produces a droplet plume from a fluid reservoir in fluid communication with the aperture plate. A change of airflow trajectory in the airflow channel and/or a fan provides inertial filtering and removal of droplets in the plume that have a mass mean aerodynamic diameter greater than 5 ?m.Type: ApplicationFiled: February 12, 2025Publication date: July 24, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Louis Thomas GERMINARIO, John H. HEBRANK, Charles Eric HUNTER, Jack C. HUNTER, Chengjie LI, Christopher W. MAURER
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Publication number: 20250235634Abstract: An electronically actuated droplet delivery device with a mouthpiece for inhaling fluid droplets includes an ejector mechanism having an electronic actuator operably coupled to an aperture plate. A fluid reservoir provided fluid to the ejector mechanism through a surface tension plate that increases contact between the fluid from the fluid reservoir and the aperture plate.Type: ApplicationFiled: February 12, 2025Publication date: July 24, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Louis Thomas GERMINARIO, John H. HEBRANK, Charles Eric HUNTER, Jack C. HUNTER, Chengjie LI, Christopher W. MAURER
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Publication number: 20250235635Abstract: An electronically actuated droplet delivery device includes a housing with a removable mouthpiece that provides a level of air resistance and is interchangeable with alternative mouthpieces that provide alternative levels of air resistance. The level of air resistance can be customized to a particular user of the droplet delivery device by using air resistance elements having different sizes and/or numbers of openings that correspond to different internal air resistance for a droplet deliver device.Type: ApplicationFiled: February 12, 2025Publication date: July 24, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Louis Thomas GERMINARIO, John H. HEBRANK, Charles Eric HUNTER, Jack C. HUNTER, Chengjie LI, Christopher W. MAURER
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Publication number: 20250235636Abstract: A method for controlling dosing of droplet delivery device includes providing a droplet delivery device, such as an inhaler, to a user, verifying a location of the user with the droplet delivery device, such as by GPS, and enabling dosing of the drug in droplets ejected from the device based on the verifying of the location of the user.Type: ApplicationFiled: February 12, 2025Publication date: July 24, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Louis Thomas GERMINARIO, John H. HEBRANK, Charles Eric HUNTER, Jack C. HUNTER, Chengjie LI, Christopher W. MAURER
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Publication number: 20250205435Abstract: An electronic droplet delivery device includes a housing including a mouthpiece located at an airflow exit side of the housing, a removable fluid reservoir, an aperture plate having a plurality of openings that receives fluid from the reservoir, an electronic actuator that oscillates the aperture plate to generate an ejected stream of droplets, and an electronic chip coupled to the fluid reservoir that communicates information applicable to use of the droplet delivery device with the fluid reservoir.Type: ApplicationFiled: February 13, 2025Publication date: June 26, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Louis Thomas GERMINARIO, John H. HEBRANK, Charles Eric HUNTER, Jack C. HUNTER, Chengjie LI, Christopher W. MAURER
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Publication number: 20250195793Abstract: A droplet delivery device includes an ejection channel and droplets outlet, a mesh positioned in the ejection channel and configured to produce an ejected stream of droplets through openings in the mesh, an airflow path in communication with the ejection channel and the mesh, and a heating element positioned in the airflow path.Type: ApplicationFiled: December 17, 2024Publication date: June 19, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Charles Eric Hunter, Michael Scoggin, Jeffrey Miller, Jose Salazar, Brian Beach, Caley Modlin, Matthew Culpepper, Jianqiang Li, Chengjie Li, Shi Bo Wang, Chao-Ping Lee, Gregory Rapp, Judson Sidney Clements
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Publication number: 20250195790Abstract: A droplet delivery device includes an ejector bracket including a mesh with a membrane operably coupled to a vibrating member tip that is coupled to an electronic transducer with the membrane between and contacting both the vibrating member tip and the mesh to produce droplets, such as for inhalation by a user of the droplet delivery device.Type: ApplicationFiled: December 17, 2024Publication date: June 19, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Charles Eric Hunter, Michael Scoggin, Jeffrey Miller, Jose Salazar, Brian Beach, Caley Modlin, Matthew Culpepper, Jianqiang Li, Chengjie Li, Shi Bo Wang, Chao-Ping Lee, Gregory Rapp, Judson Sidney Clements
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Publication number: 20250195792Abstract: A droplet delivery device includes an ejector mesh communicating with a fluid reservoir via a first pathway that includes wicking material and a second pathway that is free of wicking material with droplets produced by the mesh ejected out of a droplets outlet of the device.Type: ApplicationFiled: December 17, 2024Publication date: June 19, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Charles Eric Hunter, Michael Scoggin, Jeffrey Miller, Jose Salazar, Brian Beach, Caley Modlin, Matthew Culpepper, Jianqiang Li, Chengjie Li, Shi Bo Wang, Chao-Ping Lee, Gregory Rapp, Judson Sidney Clements
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Publication number: 20250195795Abstract: An electronic droplet delivery device includes a housing including a mouthpiece located at an airflow exit side of the housing, a removable fluid reservoir, an aperture plate having a plurality of openings that receives fluid from the reservoir, an electronic actuator that oscillates the aperture plate to generate an ejected stream of droplets, and a sensor operably coupled to trigger the actuator to generate the ejected stream of droplets when a predetermined inhalation flow rate is detected by the sensor.Type: ApplicationFiled: February 13, 2025Publication date: June 19, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Louis Thomas GERMINARIO, John H. HEBRANK, Charles Eric HUNTER, Jack C. HUNTER, Chengjie LI, Christopher W. MAURER
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Publication number: 20250195791Abstract: A droplet delivery device includes a mesh with a plurality of opening supported by a mesh carrier in the airflow path of the droplet delivery device. The mesh is vibrated by an electronic transducer and produce droplets from a fluid supply with mesh carrier aiding the production of the droplets.Type: ApplicationFiled: December 17, 2024Publication date: June 19, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Charles Eric Hunter, Michael Scoggin, Jeffrey Miller, Jose Salazar, Brian Beach, Caley Modlin, Matthew Culpepper, Jianqiang Li, Chengjie Li, Shi Bo Wang, Chao-Ping Lee, Gregory Rapp, Judson Sidney Clements
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Publication number: 20250186710Abstract: An electronic droplet delivery device having a mouthpiece of inhalation of droplets includes an aperture plate with a plurality of openings coupled to a piezoelectric actuator. A fluid reservoir supplies a solution with nicotine to the aperture plate for ejection out of the mouthpiece in a droplets stream.Type: ApplicationFiled: February 12, 2025Publication date: June 12, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Louis Thomas GERMINARIO, John H. HEBRANK, Charles Eric HUNTER, Jack C. HUNTER, Chengjie LI, Christopher W. MAURER
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Publication number: 20250186709Abstract: An electronically actuated droplet delivery device with a mouthpiece for inhaling fluid droplets includes an aperture plate with a plurality of openings. The plurality of openings includes multiple sizes to produce different sizes for targeting different locations of a user's inhalation system, such as mouth locations, throat locations, and lung locations.Type: ApplicationFiled: February 12, 2025Publication date: June 12, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Louis Thomas GERMINARIO, John H. HEBRANK, Charles Eric HUNTER, Jack C. HUNTER, Chengjie LI, Christopher W. MAURER
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Patent number: 12285559Abstract: A nasal droplet delivery device and related methods for delivering precise and repeatable dosages to a subject via the nasal passageways and sinus cavities.Type: GrantFiled: September 30, 2022Date of Patent: April 29, 2025Assignee: PNEUMA RESPIRATORY, INC.Inventors: John H. Hebrank, Christopher W. Maurer, Charles Eric Hunter, Chengjie Li, Louis Thomas Germinario
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Publication number: 20250127999Abstract: A droplet delivery device includes a droplets outlet coupled to a one-piece and removable container assembly, wherein the container assembly includes a mesh and a membrane, and wherein the mesh includes a plurality of openings formed through the mesh's thickness, a reservoir in fluid communication with the container assembly and configured to supply a volume of fluid, and a vibrating member coupled to a power source and positioned to cooperate with the membrane and mesh to generate an ejected stream of droplets through the mesh.Type: ApplicationFiled: December 17, 2024Publication date: April 24, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Charles Eric Hunter, Michael Scoggin, Jeffrey Miller, Jose Salazar, Brian Beach, Caley Modlin, Matthew Culpepper, Jianqiang Li, Chengjie Li, Shi Bo Wang, Chao-Ping Lee, Gregory Rapp, Judson Sidney Clements
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Publication number: 20250041538Abstract: A device and method for delivering a fluid as an ejected stream of droplets during inhalation uses inertial filtering to cause a first plurality of droplet particles generated by an ejector mechanism to pass through an airflow exit while a second plurality of droplet particles having a greater mass mean aerodynamic diameter than the first plurality of droplet particles fails to pass through the airflow exit.Type: ApplicationFiled: January 26, 2024Publication date: February 6, 2025Applicant: PNEUMA RESPIRATORY, INC.Inventors: Louis Thomas Germinario, John H. Hebrank, Charles Eric Hunter, Jack C. Hunter, Chengjie LI, Christopher W. Maurer
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Patent number: 12148352Abstract: The present disclosure discloses a display device and a control method thereof. The display device includes a system on board and a timing controller. The timing controller is configured to: disconnect a communication connection with the system on board when communication with the system on board is not required, and periodically output a check signal; and stop outputting the check signal when communication with the system on board is required, and establish a communication connection with the system on board after a delay of a preset duration.Type: GrantFiled: September 8, 2021Date of Patent: November 19, 2024Assignee: Shenzhen China Star Optoelectronics Semiconductor Display Technology Co., Ltd.Inventors: Chengjie Li, Wang Liu, Jinao Chen
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Publication number: 20240316291Abstract: A droplet delivery device including a face seal within a cover of the droplet delivery device to seal over an ejector mechanism when the cover couples to a mouthpiece.Type: ApplicationFiled: October 24, 2023Publication date: September 26, 2024Applicant: PNEUMA RESPRIRATORY, INC.Inventors: Charles Eric Hunter, John H. Hebrank, Chengjie Li, Judson Sidney Clements
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Publication number: 20240269397Abstract: A droplet delivery device includes a housing with a mouthpiece port or outlet from a nasal device for releasing fluid droplets, a fluid reservoir, and an ejector bracket having a membrane positioned between a mesh with a plurality of openings and a vibrating member that is coupled to an electronic transducer, such as an ultrasonic transducer. The transducer vibrates the vibrating member which causes the membrane to push fluid supplied by the reservoir through the mesh to generate droplets in an ejected stream released through the outlet.Type: ApplicationFiled: October 23, 2023Publication date: August 15, 2024Applicant: PNEUMA RESPIRATORY, INC.Inventors: Charles Eric Hunter, Michael Scoggin, Jeffrey Miller, Jose Salazar, Brian Beach, Caley Modlin, Matthew Culpepper, Jianqiang Li, Chengjie Li, Shi Bo Wang, Chao-Ping Lee, Gregory Rapp, Judson Sidney Clements
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Publication number: 20240226469Abstract: A droplet delivery device with a small volume drug ampoule and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device is configured to facilitate the ejection of small, e.g., single use, volumes of a therapeutic agent. The droplet delivery device includes a housing, a mouthpiece, a small volume drug ampoule, an ejector mechanism, and at least one differential pressure sensor. The delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a plume of droplets having an average ejected particle diameter within the respirable size range, e.g, less than about 5-6 ?m, so as to target the pulmonary system of the user.Type: ApplicationFiled: August 23, 2023Publication date: July 11, 2024Applicant: PNEUMA RESPIRATORY, INC.Inventors: John H. Hebrank, Christopher W. Maurer, Charles Eric Hunter, Chengjie Li, Louis Thomas Germinario