Abstract: The invention relates to the technical field of gene treatment and nano targeted delivery, in particular to a siRNA delivery system compound as well as a preparation method and application thereof.

Abstract: A high-voltage permanent magnet frequency conversion all-in-one machine according to an embodiment of the present disclosure includes a frequency converter configured to perform frequency conversion on a high-voltage alternating current, and output at least three alternating currents, a permanent magnet motor configured to receive the alternating currents subjected to the frequency conversion and output from the frequency converter, to drive the motor to operate, and a controller configured to control the frequency converter to perform the frequency conversion on the high-voltage alternating current, and control an operation state of the permanent magnet motor.

Abstract: A sensor for detecting virus, including virus particles and/or genetic sequences, and method of fabrication. The sensor includes a field effect transistor (FET) having source and drain electrodes formed on a substrate and a two-dimensional virus sensing transduction material (VSTM) film formed on the FET. The VSTM film is configured to collect a sample collected from a subject and comprises MXene-graphene. The VSTM film has an antibody corresponding to the virus particles to be detected linked to the film. A drain-source current response of the FET is representative of an amount of the virus particles in the sample for indicating an infection.

Abstract: Provided are a method and a device for sliding window constraint outlier-tolerant filtering noise reduction of petrochemical instrument sampling data. The method includes following steps: acquiring a petrochemical instrument sampling data sequence; obtaining a sliding window constraint function and a sliding window residual constraint function according to the petrochemical instrument sampling data sequence; and obtaining filtering and noise reduction results of instrument sampling data according to the sliding window constraint function and the sliding window residual constraint function.

Abstract: Disclosed are an Internet-of-Things device identity authentication method, apparatus and system, and a storage medium.

Abstract: An intelligent pesticide spraying robot self-adaptive to terrain of mountain land is provided. Walking mechanisms are respectively connected to both side ends of a chassis. A pesticide spraying mechanism includes rotary drive mechanisms respectively connected to both sides of the rear end of the chassis, telescopic spray boom mechanisms correspondingly connected to the rotary drive mechanisms, rotary nozzle mechanisms correspondingly connected to the telescopic spray boom mechanisms, a liquid pesticide storage box fixed to the top of the chassis, a first water pump fixed in the liquid pesticide storage box, and first water pipes in communication with the first water pump and the rotary nozzle mechanisms. A control chip of a control identification mechanism is communicatively connected to the walking mechanisms, the rotary drive mechanisms, the telescopic spray boom mechanisms, the rotary nozzle mechanisms, the first water pump, a front-end camera, side-end cameras and ultrasonic sensors respectively.

Abstract: Disclosed is an autonomous mining method of industrial big data based on model sets, which comprises the following steps: S1, building model sets and a mining engine based on domain knowledge and structural characteristics of multi-source heterogeneous data; S2, carrying out data sampling on the multi-source heterogeneous data, and counting the fault-tolerant estimation of random error variance; S3, mining data sets by using the mining engine, and determining the optimal fault-tolerant model of each sampled data sequence and the optimal fault-tolerant estimation of model parameters; S4, performing goodness-of-fit statistics calculation and VV&A test by using the optimal fault-tolerant model; S5, acquiring data model representation and connotation knowledge based on model clustering. The method can realize the automation of the mining process of big data, the integration of associated knowledge, the expansion of model sets, the integration of mining and modeling and the optimization of mining results.

Abstract: A stroboscopic stepped illumination defect detection system for appearance defect detection of a product is provided. The system includes an image extraction unit, a brightness adjustment unit, a data processing unit, and a stroboscopic control unit. The image extraction unit is connected to the stroboscopic control unit and used for obtaining stable and clear images in various transmission/reflection visual bright fields/dark fields; and the brightness adjustment unit is connected to the stroboscopic control unit and used for setting various transmission/reflection visual bright fields/dark fields and converting in the various transmission/reflection visual bright fields/dark fields.

Abstract: The invention relates to a 2-isopropyl malate synthase, a genetically engineered bacterium for producing L-leucine and application thereof and belongs to the field of metabolic engineering. The genetically engineered bacterium is obtained by overexpressing an isopropyl malate synthase coding gene leuAM for relieving feedback inhibition by L-leucine, an acetohydroxy acid synthase coding gene ilvBNM for relieving feedback inhibition by L-isoleucine, a 3-isopropyl malate dehydrogenase coding gene leuB and a 3-isopropyl malate dehydratase coding gene leuCD in host cells. The genetically engineered bacterium for producing the L-leucine is free from nutritional deficiency, rapid in growth, short in fermentation period, high in yield and high in conversion rate.

Abstract: A PIN diode detector includes a substrate. The PIN diode detector further includes a plurality of PIN diode wells in a pixel region, wherein each of the plurality of PIN diode wells has a first dopant type. The PIN diode detector further includes a connecting ring well and a plurality of floating ring wells in a peripheral region, wherein the connecting ring well and plurality of floating ring wells have the first dopant type. The PIN diode detector further includes a field stop ring well surrounding the plurality of floating ring wells, wherein the field stop ring well has a second dopant type opposite the first dopant type. The PIN diode detector further includes a blanket doped region. The blanket doped region extends continuously through an entirety of the pixel region and an entirety of the peripheral region, and the blanket doped region has the second dopant type.

Abstract: The invention relates to the technical field of gene treatment and nano targeted delivery, in particular to a siRNA delivery system compound as well as a preparation method and application thereof.

Abstract: The present disclosure relates to a genetically engineered strain with high production of uridine and its construction method and application. The strain was constructed as follows: heterologously expressing pyrimidine nucleoside operon sequence pyrBCAKDFE (SEQ ID NO:1) on the genome of E coli prompted by strong promoter Ptrc to reconstruct the pathway of uridine synthesis; overexpressing the autologous prsA gene coding PRPP synthase by integration of another copy of prsA gene promoted by strong promoter Ptrc on the genome; deficiency of uridine kinase, uridine phosphorylase, ribonucleoside hydrolase, homoserine dehydrogenase I and ornithine carbamoyltransferase. When the bacteria was used for producing uridine, 40-67 g/L uridine could be obtained in a 5 L fermentor after fermentation for 40-70 h using the technical scheme provided by the disclosure with the maximum productivity of 0.15-0.25 g uridine/g glucose and 1.

Abstract: The invention relates to a 2-isopropyl malate synthase, a genetically engineered bacterium for producing L-leucine and application thereof and belongs to the field of metabolic engineering. The genetically engineered bacterium is obtained by overexpressing an isopropyl malate synthase coding gene leuAM for relieving feedback inhibition by L-leucine, an acetohydroxy acid synthase coding gene ilvBNM for relieving feedback inhibition by L-isoleucine, a 3-isopropyl malate dehydrogenase coding gene leuB and a 3-isopropyl malate dehydratase coding gene leuCD in host cells. The genetically engineered bacterium for producing the L-leucine is free from nutritional deficiency, rapid in growth, short in fermentation period, high in yield and high in conversion rate.

Abstract: The present application provides a method and system for calibration of structural parameters and construction of an affine coordinate system of a vision measurement system. The method comprises the following steps: S1, for the same image, performing bundle adjustment on front points and corresponding image points to acquire rear intersection point coordinates; S2, acquiring world coordinate of a front principal point corresponding to an intersection point; S3, performing the steps S1 and S2 cyclically by utilizing a plurality of different calibrated images to acquire a plurality of pairs of intersection point coordinates and world coordinates of front projection points; S4, performing tangent co-spherical second intersection adjustment by utilizing the pairs of intersection point coordinate and world coordinate of front projection point to acquire structural parameters and coordinate of rotation center of the pan-tilt of the vision measurement system; and S5, establishing an affine space coordinate system.

Abstract: The present disclosure relates to a genetically engineered strain with high production of uridine and its construction method and application. The strain was constructed as follows: heterologously expressing pyrimidine nucleoside operon sequence pyrBCAKDFE (SEQ ID NO:1) on the genome of E coli prompted by strong promoter Ptrc to reconstruct the pathway of uridine synthesis; overexpressing the autologous prsA gene coding PRPP synthase by integration of another copy of prsA gene promoted by strong promoter Ptrc on the genome; deficiency of uridine kinase, uridine phosphorylase, ribonucleoside hydrolase, homoserine dehydrogenase I and ornithine carbamoyltransferase. When the bacteria was used for producing uridine, 40-67 g/L uridine could be obtained in a 5 L fermentator after fermentation for 40-70 h using the technical scheme provided by the discloure with the maximum productivity of 0.15-0.25 g uridine/g glucose and 1.

Abstract: A method for channel selection in a communication system includes receiving a broadcast signal comprising a beam vector, generating a first channel state information message based on the power of the broadcast signal, generating a second channel state information message based on the direction of the broadcast signal with respect to the beam vector, and transmitting a feedback signal comprising at least the first channel state information message and the second channel state information message. The communication system may include a frequency division duplex (FDD) multiuser communication system or a time division duplex (TDD) multiuser communication system. The first channel state information message may include a channel gain with respect to the broadcast signal. The second channel state information message may include a measure of orthogonality between the broadcast signal and the beam vector.

Abstract: A peer-to-peer communication system for use over an underlying computer network system, the peer-to-peer communication system comprising: a web browser; and a broker interposed between the browser and the underlying computer network system, with the broker being adapted to (1) monitor a first event taking place within the browser, encode the first event and associated changes in a first event message, and push the first event message to the at least one other peer over the underlying computer network system.

Abstract: A peer-to-peer communication system for use over an underlying computer network system, the peer-to-peer communication system comprising: at least two peers, each peer comprising: a Web browser; and a broker interposed between the browser and the underlying computer network system, with the broker being adapted to (1) monitor a first event taking place within the browser, encode the first event and associated changes in a first event message, and push the first event message to the at least one other peer over the underlying computer network system, whereby the at least one other peer can reproduce on the at least one other peer the changes associated with the first event; and (2) receive a second event message from the at least one other peer, where the second event message has been encoded to correspond to a second event and associated changes taking place on the at least one other peer, decode the second event message and push the results to the browser, whereby to recreate the changes associated with the