Patents by Inventor Chengrong Wang
Chengrong Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220144874Abstract: The disclosure provides a method for preparing an amphiphilic lignin nanomaterial based on pulping black liquor, an amphiphilic lignin nanomaterial, and an oil sludge detergent. In the disclosure, physical treatments such as ball milling and high-pressure jet homogenization treatment are conducted on alkali lignin at the early stage to adjust the molecular weight and size of alkali lignin and thus to give alkali lignin nanoparticles with uniform particle sizes; and on this basis, a chemical treatment such as alkylation grafting modification is conducted to give amphiphilic lignin nanoparticles with both hydrophilicity and lipophilicity. Due to the nano-size effect, the amphiphilic lignin nanomaterial has a significantly-increased specific surface area (SSA) and effectively-improved surface properties, which can reduce the oil-water interfacial tension, and emulsify the crude oil and peel off the crude oil from the surface of rock particles, so as to achieve the purpose of oil-solid separation.Type: ApplicationFiled: November 11, 2020Publication date: May 12, 2022Inventors: Chengrong QIN, Jian ZHANG, Chen LIANG, Shuangquan YAO, Xinliang LIU, Zhiwei WANG, Wei LI, Jiulong SHA
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Patent number: 11225611Abstract: Disclose is an online analyzer to monitor conversion of a biofeedstock in a first hydrotreating stage to avoid catalyst poisoning in a subsequent stage. An example method of processing a biofeedstock may comprise hydrotreating the biofeedstock by reaction with hydrogen to form a hydrotreated biofeedstock. The method may further comprise monitoring conversion of the biofeedstock in the hydrotreating with an online analyzer.Type: GrantFiled: July 8, 2020Date of Patent: January 18, 2022Assignee: ExxonMobil Research and Engineering CompanyInventors: Chengrong Wang, Anding Zhang, Xiaochun Xu, Samuel J. Cady, Shifang Luo, Michael H. Ring, Maria Vanessa C. Aguinaldo, John Della Mora, Kegun L. Ream
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Publication number: 20220010219Abstract: Disclose is an online analyzer to monitor conversion of a biofeedstock in a first hydrotreating stage to avoid catalyst poisoning in a subsequent stage. An example method of processing a biofeedstock may comprise hydrotreating the biofeedstock by reaction with hydrogen to form a hydrotreated biofeedstock. The method may further comprise monitoring conversion of the biofeedstock in the hydrotreating with an online analyzer.Type: ApplicationFiled: July 8, 2020Publication date: January 13, 2022Inventors: Chengrong Wang, Anding Zhang, Xiaochun Xu, Samuel J. Cady, Shifang Luo, Michael H. Ring, Maria Vanessa C. Aguinaldo, John Della Mora, Kegun L. Ream
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Publication number: 20210262995Abstract: The present disclosure relates to methods for compositional analysis of algal biomass, specifically weight percent elemental composition. In at least one embodiment, a method for compositional analysis of an algae sample includes flash combusting a first portion of the algae sample to provide a carbon wt %, a hydrogen wt %, and a nitrogen weight %. The method includes pyrolysing a second portion of the algae sample to provide an oxygen wt %. The method includes scanning a third portion of the algae sample using x-ray fluorescence to provide an elemental intensity. The method includes normalizing the elemental intensity using the carbon wt %, the hydrogen wt %, the nitrogen wt %, and/or the oxygen wt %.Type: ApplicationFiled: January 6, 2021Publication date: August 26, 2021Inventors: Anding Zhang, Kuangnan Qian, Chengrong Wang, Amy C. Clingenpeel
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Publication number: 20210255125Abstract: A method and system for direct quantification of the concentration of biomolecules in algal biomass. The biomolecules include lipids, proteins, and carbohydrates. An algae slurry is cultivated within a cultivation vessel, and algal biomass is harvested therefrom. A portion of biomass is analyzed using solvent-lipid analysis to extract lipids and nuclear magnetic resonance spectroscopy is used to quantify the biomolecular concentration of the biomass.Type: ApplicationFiled: January 6, 2021Publication date: August 19, 2021Inventors: Hao Wang, Chengrong Wang, Amy C. Clingenpeel, Kuangnan Qian
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Patent number: 10774286Abstract: The present disclosure provides a grease composition with improved water resistance and mechanical stability at high-temperatures, including: at least one base oil; a water insoluble thickener; and a low molecular weight thixotropic polyamide composition having molecular weight distribution characteristics meeting the requirement described by the relationship: ( A + D ) ( B + C ) ? 0.05 where A=the % mass of the polyamide composition with a molecular weight greater than 1700 AMU; B=the % mass of the polyamide composition with a molecular weight between 1100 AMU and 1300 AMU; C=the % mass of the polyamide composition with a molecular weight between 700 AMU and 1000 AMU; and D=the % mass of the polyamide composition with a molecular weight of 600 AMU or lower (determined by GPC). The grease composition of the present disclosure provides a less than 50 penetration point change as determined by ASTM-D7342, a less than 10 mg weight loss as determined by ASTM-D4170, or both.Type: GrantFiled: December 12, 2018Date of Patent: September 15, 2020Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Sarvesh K. Agrawal, James E. Spagnoli, Chengrong Wang
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Publication number: 20200199480Abstract: A method for controlling formation and dissipation of at least one oligomeric or polymeric aminic antioxidant in a lubricating oil, during operation of an engine or other mechanical component lubricated with the lubricating oil by using as the lubricating oil a formulated oil. The formulated oil has a composition including a lubricating oil base stock as a major component, and at least one oligomeric or polymeric aminic antioxidant, as a minor component. The at least one oligomeric or polymeric aminic antioxidant is formed over time in situ from at least one monomeric aminic antioxidant during operation of the engine or other mechanical component. The at least one oligomeric or polymeric aminic antioxidant is dissipated over time in the lubricating oil during operation of the engine or other mechanical component. The at least one monomeric aminic antioxidant is present in an amount from greater than 2 to 10 wt. % of the lubricating oil.Type: ApplicationFiled: December 19, 2019Publication date: June 25, 2020Inventors: Andrew E. Taggi, Chengrong Wang
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Publication number: 20200199483Abstract: A method for improving viscosity control, while maintaining or improving deposit control and cleanliness, of a lubricating oil in an engine or other mechanical component lubricated with the lubricating oil by using as the lubricating oil a formulated oil. The formulated oil has a composition including a lubricating oil base stock as a major component, and at least one oligomeric or polymeric aminic antioxidant, as a minor component. The at least one oligomeric or polymeric aminic antioxidant is formed in situ from at least one monomeric aminic antioxidant during operation of the engine or other mechanical component. The at least one monomeric aminic antioxidant is present in an amount sufficient to form in situ the at least one oligomeric or polymeric aminic antioxidant during operation of the engine or other mechanical component.Type: ApplicationFiled: December 19, 2019Publication date: June 25, 2020Inventors: Andrew E. Taggi, Chengrong Wang
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Publication number: 20190203149Abstract: The present disclosure provides a grease composition with improved water resistance and mechanical stability at high-temperatures, including: at least one base oil; a water insoluble thickener; and a low molecular weight thixotropic polyamide composition having molecular weight distribution characteristics meeting the requirement described by the relationship: ( A + D ) ( B + C ) ? 0.05 where A=the % mass of the polyamide composition with a molecular weight greater than 1700 AMU; B=the % mass of the polyamide composition with a molecular weight between 1100 AMU and 1300 AMU; C=the % mass of the polyamide composition with a molecular weight between 700 AMU and 1000 AMU; and D=the % mass of the polyamide composition with a molecular weight of 600 AMU or lower (determined by GPC). The grease composition of the present disclosure provides a less than 50 penetration point change as determined by ASTM-D7342, a less than 10 mg weight loss as determined by ASTM-D4170, or both.Type: ApplicationFiled: December 12, 2018Publication date: July 4, 2019Inventors: Sarvesh K. AGRAWAL, James E. SPAGNOLI, Chengrong WANG
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Patent number: 7691647Abstract: Compositions suitable for use as signal generation components of an immunoassay, and methods for their use. According to one aspect of the invention, the composition includes a carrier having a coating of an aminodextran and a metal chelate incorporated therein. The metal chelate is present in the amount of at least 0.065 ?Mole per gram of carrier, and the aminodextran coating density averaging at least about 45 ?g per milligram of carrier. In another aspect of the invention, carrier is dyed with a complex having the formula: M(L1)x(L2)y, wherein M is a metal selected from the group consisting of europium, terbium, dysprosium, samarium, osmium and ruthenium; L1 is a ligand selected from the group consisting of DPP, TOPO, TPPO; L2 comprises a ligand having the formula wherein R is one or more substituents, each substituent comprising an electron donating group; n=2-10; x=1-2; and y=2-4.Type: GrantFiled: August 4, 2006Date of Patent: April 6, 2010Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Alan R. Craig, Zhu Teng, Richard C. Wright, Chengrong Wang
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Publication number: 20090325316Abstract: Compositions suitable for use as signal generation components of an immunoassay, and methods for their use. According to one aspect of the invention, the composition includes a carrier having a coating of an aminodextran and a metal chelate incorporated therein. The metal chelate is present in the amount of at least 0.065 ?M per milligram of carrier, and the aminodextran coating density averaging at least about 45 ?g per milligram of carrier. In another aspect of the invention, carrier is dyed with a complex having the formula: M(L1)x(L2)y, wherein M is a metal selected from the group consisting of europium, terbium, dysprosium, samarium, osmium and ruthenium; L1 is a ligand selected from the group consisting of DPP, TOPO, TPPO; L2 comprises a ligand having the formula wherein R is one or more substituents, each substituent comprising an electron donating group; n=2-10; x=1-2; and y=2-4.Type: ApplicationFiled: September 8, 2009Publication date: December 31, 2009Applicant: SIEMENS HEALTHCARE DIAGNOSTICSInventors: Alan R. Craig, Zhu Teng, Richard C. Wright, Chengrong Wang
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Patent number: 7186518Abstract: New derivatives of FK 506 are disclosed. These new derivatives and other derivatives that are useful for determining the levels of FK 506 in a sample are also provided as are assay procedures and kits for use in determining the levels of FK 506 or other macrophilin binding substances in blood, particularly un-extracted blood in the presence of specific binding proteins for FK 506.Type: GrantFiled: November 21, 2003Date of Patent: March 6, 2007Assignee: Dade Behring Inc.Inventors: Chengrong Wang, Tie Q. Wei, Zhu Teng
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Publication number: 20060270063Abstract: Compositions suitable for use as signal generation components of an immunoassay, and methods for their use. According to one aspect of the invention, the composition includes a carrier having a coating of an aminodextran and a metal chelate incorporated therein. The metal chelate is present in the amount of at least 0.065 ?M per milligram of carrier, and the aminodextran coating density averaging at least about 45 ?g per milligram of carrier. In another aspect of the invention, carrier is dyed with a complex having the formula: M(L1)x(L2)y, wherein M is a metal selected from the group consisting of europium, terbium, dysprosium, samarium, osmium and ruthenium; L1 is a ligand selected from the group consisting of DPP, TOPO, TPPO; L2 comprises a ligand having the formula wherein R is one or more substituents, each substituent comprising an electron donating group; n=2-10; x=1-2; and y=2-4.Type: ApplicationFiled: August 4, 2006Publication date: November 30, 2006Inventors: Alan Craig, Zhu Teng, Richard Wright, Chengrong Wang
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Publication number: 20060166376Abstract: Compositions suitable for use as signal generation components of an immunoassay, and methods for their use. According to one aspect of the invention, the composition includes a carrier having a coating of an aminodextran and a metal chelate incorporated therein. The metal chelate is present in the amount of at least 0.065 ?M per milligram of carrier, and the aminodextran coating density averaging at least about 45 ?g per milligram of carrier. In another aspect of the invention, carrier is dyed with a complex having the formula: M (L1)x(L2)y, wherein M is a metal selected from the group consisting of europium, terbium, dysprosium, samarium, osmium and ruthenium; L1 is a ligand selected from the group consisting of DPP, TOPO, TPPO; L2 comprises a ligand having the formula wherein R is one or more substituents, each substituent comprising an electron donating group; n=2?10; x=1?2; and y=2?4.Type: ApplicationFiled: January 21, 2005Publication date: July 27, 2006Inventors: Alan Craig, Zhu Teng, Richard Wright, Chengrong Wang
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Publication number: 20050158877Abstract: Assay reagents include small metallic particles labeled with a Raman dye and antibody molecules capable of binding the analyte of interest. In the absence of the analyte, the size of the isolated metallic particles is so small that no significant SERS signal can be detected. An analyte molecule binds two metallic particles together through the formation of a sandwich complex, and then more metallic particles are clustered together by the analyte if each metallic particle contains more than two antibodies on the surface. The bonded metallic particles form a cluster structure, which significantly amplifies the SERS effect.Type: ApplicationFiled: January 6, 2005Publication date: July 21, 2005Inventors: Chengrong Wang, Sean Wang, Qun Li
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Publication number: 20050112778Abstract: New derivatives of FK 506 are disclosed. These new derivatives and other derivatives that are useful for determining the levels of FK 506 in a sample are also provided as are assay procedures and kits for use in determining the levels of FK 506 or other macrophilin binding substances in blood, particularly un-extracted blood in the presence of specific binding proteins for FK 506.Type: ApplicationFiled: November 21, 2003Publication date: May 26, 2005Inventors: Chengrong Wang, Tie Wei, Zhu Teng
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Patent number: 6391175Abstract: The invention pertains to a novel ionophore having the general structure: wherein R1, R2, R3 and R4 are independently straight or branched chain alkyl having 4 to 12 carbon atoms or the alkyl groups may optionally contain a cycloalkyl group having 3 to 8 carbon atoms or R1 and R2 or R3 and R4 together with N to which they are attached, can form a ring having 5 to 8 carbon atoms. This ionophore has increased selectivity for carbonate ions over other ions, especially salicylate. The invention includes membranes containing effective amounts of the novel ionophores and -sensors containing these membranes.Type: GrantFiled: November 21, 2000Date of Patent: May 21, 2002Assignee: Dade Behring Inc.Inventors: Chengrong Wang, Daniel Brown
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Particle reagents having reduced matrix effects and containing an aldehyde-reactive functional group
Patent number: 6231982Abstract: The invention is directed to the preparation of magnetic and non-magnetic particles coated with a polyaldehyde dextran material and a process for making the same. The polyaldehyde dextran coated particles of the invention are suitable for use in immunological assays and exhibit a reduced matrix effect in such assays when compared to convention particles without a polyaldehyde dextran coating.Type: GrantFiled: December 10, 1997Date of Patent: May 15, 2001Assignee: Dade Behring Inc.Inventor: Chengrong Wang -
Patent number: 6207398Abstract: The present invention provides novel cyclosporine C (CsC) derivatives having improved protein conjugatibility and hydrolytic stability. The present invention further provides a CsC derivative conjugated to a carrier, e.g., a solid support. Preferably, the solid support is a latex or magnetic particle.Type: GrantFiled: August 11, 1999Date of Patent: March 27, 2001Assignee: Dade Behring Inc.Inventor: Chengrong Wang
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Patent number: 6015480Abstract: A method for extending the uselife of a chloride ion selective membrane of an ISE sensor by providing a two-layer sensor structure wherein an quaternized ion-selective polymeric layer is positioned between a sample to be analyzed and a conventional polymeric ISE membrane containing an ion-exchange agent. Also provided are polymer compositions comprised methyl methacrylate/choloromethyl styrene copolymer and mixtures thereof that have been reacted with tertiary amines.Type: GrantFiled: September 4, 1997Date of Patent: January 18, 2000Assignee: Dade Behring Inc.Inventors: Alan Robert Craig, Michael Patrick Reidy, Chengrong Wang