Abstract: A nanobody capable of specifically recognizing SARS-CoV-2 spike glycoprotein RBD is provided, and the nanobody comprises a CDR having an amino acid sequence selected from at least one of the following or at least 95% identical to the following: a CDR sequence of a heavy chain variable region: SEQ ID NO: 1˜21.

Abstract: An on-site reciprocity calibration method for a piezoelectric accelerometer, including a vibration test and a reciprocity test. In the vibration test, a sine excitation with a corresponding frequency and amplitude is provided by a vibration exciting device to the piezoelectric accelerometer fixed on a motion plane, and output signals of a drive port and a signal port of the reciprocal piezoelectric accelerometer are collected by a data acquisition device. In the reciprocity test, a sine voltage excitation is provided by a signal generator to the drive port, and then an excitation signal and an output signal of the signal port are collected by the data acquisition device. An amplitude ratio of the two signals is obtained based on signal sine-fitting. Finally, the on-site calibration is enabled according the sensitivity amplitude ratio obtained in the vibration test and the sensitivity amplitude product obtained in the reciprocity test.

Abstract: The present disclosure provides antibodies that bind to OX40 and antigen binding fragments thereof, and use of the antibodies and the antigen binding fragments in the treatment of diseases for example cancers. The antibodies or the antigen binding fragments include a heavy chain variable region including one or more CDRs having an amino acid sequence selected from amino acid sequences as set forth in SEQ ID NOs: 1-12.

Abstract: A method for measuring angular velocity and angular acceleration based on monocular vision. Firstly, a movement sequence image of a feature mark fixed on a working table of a rotary motion generating device is acquired via an acquisition and imaging device. Secondly, a region of interest on the movement sequence image of the feature mark under different shooting distances and rotating conditions is determined by cyclic matching between a set of circular templates and the movement sequence image of the feature mark. Then, a sub-pixel of feature line edges in the region of interest is extracted using a line segment detection method, and only the feature line edges in a motion direction are retained through a constraint of the number of edge points. Finally, the angular velocity and angular acceleration are calculated by using the extracted feature line edges in the motion direction.

Abstract: A six-degree-of-freedom measurement method by machine vision based on physical decoupling. A point projector capable of emitting three laser beams perpendicular to each other is placed on a measured object. A rear-projection screen is configured to allow the three laser beams to be projected thereon as three laser points. The collection of motion images is performed by a camera. Plane coordinates of the three laser points are obtained by processing a sequence image. A mathematical decoupling model is built according to a nature of sphere and a spatial position relationship of three laser beams. The plane coordinates of the three laser points are input into the mathematical decoupling model to obtain six-degree-of-freedom information of the measured object.

Abstract: A method for calibrating linear vibration and angular vibration based on monocular vision. A motion sequence image of a feature mark is acquired by an industrial camera, and an output signal of a linear and angular accelerometer is acquired by a data acquisition card, where the feature mark and the linear and angular accelerometer are fixed on a work table. An exciting acceleration of the linear and angular accelerometer is measured by a monocular vision method integrating a camera calibration method and a sub-pixel edge extraction method based on line segment detection. The exciting acceleration and the output signal are fitted by a sine approximation method, respectively, and corresponding fitted peaks are obtained. A sensitivity of the linear and angular accelerometer is obtained according to the fitted peaks.

Abstract: The present disclosure provides antibodies that bind to OX40 and antigen binding fragments thereof, and use of the antibodies and the antigen binding fragments in the treatment of diseases for example cancers. The antibodies or the antigen binding fragments include a heavy chain variable region including one or more CDRs having an amino acid sequence selected from amino acid sequences as set forth in SEQ ID NOs: 1-12.

Abstract: A method for measuring angular velocity and angular acceleration based on monocular vision. Firstly, a movement sequence image of a feature mark fixed on a working table of a rotary motion generating device is acquired via an acquisition and imaging device. Secondly, a region of interest on the movement sequence image of the feature mark under different shooting distances and rotating conditions is determined by cyclic matching between a set of circular templates and the movement sequence image of the feature mark. Then, a sub-pixel of feature line edges in the region of interest is extracted using a line segment detection method, and only the feature line edges in a motion direction are retained through a constraint of the number of edge points. Finally, the angular velocity and angular acceleration are calculated by using the extracted feature line edges in the motion direction.

Abstract: A method for calibrating linear vibration and angular vibration based on monocular vision. A motion sequence image of a feature mark is acquired by an industrial camera, and an output signal of a linear and angular accelerometer is acquired by a data acquisition card, where the feature mark and the linear and angular accelerometer are fixed on a work table. An exciting acceleration of the linear and angular accelerometer is measured by a monocular vision method integrating a camera calibration method and a sub-pixel edge extraction method based on line segment detection. The exciting acceleration and the output signal are fitted by a sine approximation method, respectively, and corresponding fitted peaks are obtained. A sensitivity of the linear and angular accelerometer is obtained according to the fitted peaks.

Abstract: A monocular vision-based method for measuring displacement and trajectory of planar motion. In this method, a sequence image of a motion of a high-contrast feature mark fixed on a moving plane to be measured is collected using a camera. A sub-pixel coordinate of a feature edge of a linear motion of the sequence in an X direction and a Y direction is extracted using a sub-pixel edge detection method, and the sub-pixel coordinate is converted into a corresponding world coordinate. The world coordinate of the feature edge is fitted based on a least squares principle to obtain a straight line of the feature edge to realize decoupling measurement of a displacement in the X direction and the Y direction. The planar motion trajectory is obtained through measuring the displacement in the X direction and the Y direction.

Abstract: A six-degree-of-freedom measurement method by machine vision based on physical decoupling. A point projector capable of emitting three laser beams perpendicular to each other is placed on a measured object. A rear-projection screen is configured to allow the three laser beams to be projected thereon as three laser points. The collection of motion images is performed by a camera. Plane coordinates of the three laser points are obtained by processing a sequence image. A mathematical decoupling model is built according to a nature of sphere and a spatial position relationship of three laser beams. The plane coordinates of the three laser points are input into the mathematical decoupling model to obtain six-degree-of-freedom information of the measured object.

Abstract: A method for calibrating phase-frequency characteristics of low frequency accelerometer based on time-spatial synchronization, comprises: measuring excitation displacement of the low frequency accelerometer to realize excitation acceleration measurement of the low frequency accelerometer; realizing alignment of the excitation acceleration signal of the low frequency accelerometer with output voltage signal of the low frequency accelerometer in the spatial domain based on TSS technology, fitting the excitation acceleration signal and the output voltage signal respectively by SAM, and calculating phase ?F of the excitation acceleration signal at a zero position of horizontal long-stroke shaker and phase ?Z of the output voltage signal at the time when a zero encoder on the shaker outputs pulse; and calculating the sensitivity phase of the low frequency accelerometer with ?Z and ?F, and determining phase-frequency characteristics of the low frequency accelerometer by calibrating the sensitivity phases at differe

Abstract: A method for calibrating phase-frequency characteristics of low frequency accelerometer based on time-spatial synchronization, comprises: measuring excitation displacement of the low frequency accelerometer to realize excitation acceleration measurement of the low frequency accelerometer; realizing alignment of the excitation acceleration signal of the low frequency accelerometer with output voltage signal of the low frequency accelerometer in the spatial domain based on TSS technology, fitting the excitation acceleration signal and the output voltage signal respectively by SAM, and calculating phase ?F of the excitation acceleration signal at a zero position of horizontal long-stroke shaker and phase ?Z of the output voltage signal at the time when a zero encoder on the shaker outputs pulse; and calculating the sensitivity phase of the low frequency accelerometer with ?Z and ?F, and determining phase-frequency characteristics of the low frequency accelerometer by calibrating the sensitivity phases at differe

Abstract: The present disclosure discloses a method for performing an ADC phase-frequency response test including: measuring a time delay of an analog mixer and low-pass filter (MLPF) in down-converting a specific carrier frequency narrowband frequency modulation (FM) signal; determining an effective sampling frequency required by an ADC for acquiring FM signals; acquiring a high carrier frequency FM signal and a low carrier frequency FM signal before and after down-conversion is performed by the analog MLPF; and demodulating the FM signals that are acquired, correcting an initial phase of a modulation signal of the high carrier frequency FM signal and an initial phase of a modulation signal of the low carrier frequency FM signal, and calculating a phase-frequency response of the ADC at a high carrier frequency. The present disclosure has advantages of a simple test process, a wide frequency range with frequencies and a test simultaneously performed on multiple channels.

Abstract: A sound producing apparatus with multi-directivity has two or more speakers to produce music or other types of audio sounds. Each of the speakers can produce audio sounds in a certain direction and at least one speaker is steerable so that its sound propagation direction relative to the others can be changed. Furthermore, one or more speakers can produce audio sounds in an adjustable angular range. One or more of the speakers can be dual-mode speakers, each of which can be operated as a wide-angle speaker or a narrow-angle speaker. With multi-directivity, it is possible to play one type of music in one direction and another type of music in another direction to suit the interests of the audience. The apparatus can be a mobile phone, an audio player, a digital or analog recorder/player, or the like.

Abstract: Apparatus including a first liquid crystal layer configured to receive at least a portion of an image and to provide the portion of the image across an angular viewing range; first substantially transparent electrodes positioned adjacent the first liquid crystal layer, the first electrodes being configured to have at least a first configuration in which a first subset of the electrodes provide electric fields across the first liquid crystal layer to form first transparent regions and first opaque regions in the first liquid crystal layer to provide a first angular viewing range, and a second configuration in which a second subset of the electrodes provide electric fields across the first liquid crystal layer to form second different transparent regions and second different opaque regions in the first liquid crystal layer to provide a second angular viewing range, having a different angular viewing range to the first angular viewing range.

Abstract: Apparatus including a first liquid crystal layer configured to receive at least a portion of an image and to provide the portion of the image across an angular viewing range; first substantially transparent electrodes positioned adjacent the first liquid crystal layer, the first electrodes being configured to have at least a first configuration in which a first subset of the electrodes provide electric fields across the first liquid crystal layer to form first transparent regions and first opaque regions in the first liquid crystal layer to provide a first angular viewing range, and a second configuration in which a second subset of the electrodes provide electric fields across the first liquid crystal layer to form second different transparent regions and second different opaque regions in the first liquid crystal layer to provide a second angular viewing range, having a different angular viewing range to the first angular viewing range.

Abstract: An apparatus uses a transducer to produce vibration in the ultrasonic frequency range and in the audible frequency range. A membrane or cantilever structure is coupled to the transducer to produce acoustic waves. When the vibration is in the audible frequency range, the membrane structure works like a conventional loudspeaker. When the vibration is in the ultrasonic frequency range, the ultrasonic signal is modulated by audio signal for creating better directivity. The acoustic waves in the ultrasonic frequency range can reproduce directional audible sound due to the nonlinear interaction of ultrasonic waves in air.

Abstract: A sound producing apparatus with multi-directivity has two or more speakers to produce music or other types of audio sounds. Each of the speakers can produce audio sounds in a certain direction and at least one speaker is steerable so that its sound propagation direction relative to the others can be changed. Furthermore, one or more speakers can produce audio sounds in an adjustable angular range. One or more of the speakers can be dual-mode speakers, each of which can be operated as a wide-angle speaker or a narrow-angle speaker. With multi-directivity, it is possible to play one type of music in one direction and another type of music in another direction to suit the interests of the audience. The apparatus can be a mobile phone, an audio player, a digital or analog recorder/player, or the like.

Abstract: Methods, apparatuses, and systems for processing tactile input received at a display are disclosed. An apparatus may include a display comprising a tactile sensor and a display screen. The tactile sensor may include a top layer comprising a first plurality of resistive strips, wherein each of the resistive strips in the top layer are spaced apart from one another, a bottom layer comprising a second plurality of resistive strips, wherein each of the resistive strips in the bottom layer are spaced apart from one another, and a separator positioned between the first plurality of resistive strips of the top layer and the second plurality of resistive strips of the bottom layer, wherein the tactile sensor is configured to receive a tactile input to cause at least one of the resistive strips of the top layer to contact at least one of the plurality of resistive strips of the bottom layer.