Abstract: The present invention provides a method for biological and chemical synthesis of tetrodotoxin, specifically comprising the following steps: using cheap and easily available benzyl acetate as a raw material, and performing biological fermentation to obtain an optically pure intermediate ((5S, 6R)-5, 6-dihydroxycyclohexa-1, 3-dienyl) methyl acetate (formula I); and performing a series of chemical conversions on the intermediate to finally obtain tetrodotoxin at a purity of 95% or more without purifying the product. The present invention has the potential of large-scale production, and is an excellent alternative to the existing extraction method from a pufferfish.

Abstract: A 3D inversion method of DC method using seismic data constraints is disclosed, comprising processing of seismic data and inversion processing of resistivity data; by utilizing seismic wave interval velocity information to constrain the high-density electrical inversion, which can play a complementary role to a certain extent, it is beneficial to supplement the resolution of resistivity inversion with 3D seismic image information, reflect a boundary of subsurface electrical anomalous body, and further characterizes the boundary characteristics of anomalous body through comprehensive geological-geophysical analysis. Seismic data constraints are applied to 3D resistivity inversion, performing numerical simulation and inversion of electrical data under undulating terrain using the finite volume method and Gauss-Newton inversion method.

Abstract: A beam failure recovery method for multi-transmission and reception points includes performing, by a terminal, a first operation in a case that beam failure occurs on at least some of multiple TRPs. The first operation includes one or more of following: measuring a candidate beam reference signal to determine a new beam; and sending a first message on one or multiple first resources. The first message includes an SR and/or a BFR MAC CE.

Abstract: The present invention provides a method for biological and chemical synthesis of tetrodotoxin, specifically comprising the following steps: using cheap and easily available benzyl acetate as a raw material, and performing biological fermentation to obtain an optically pure intermediate ((5S, 6R)-5, 6-dihydroxycyclohexa-1, 3-dienyl) methyl acetate (formula I); and performing a series of chemical conversions on the intermediate to finally obtain tetrodotoxin at a purity of 95% or more without purifying the product. The present invention has the potential of large-scale production, and is an excellent alternative to the existing extraction method from a pufferfish.