Patents by Inventor Chengye LI

Chengye LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250029016
    Abstract: A new linear machine learning method based on DNA hybridization reaction technology, includes a machine learning training part, an algorithm part, and a testing part. This machine learning method has the ability to learn linear functions. Unlike silicon circuits, the learning algorithm is implemented through the synchronization of DNA hybridization reactions. Therefore, the calculation mode of this machine learning method is a parallel computing model, and the weights of this machine learning are obtained through training without the involvement of electronic computers. Through the method, it is possible to learn multivariable linear functions without any limitation on the number of input terms. Due to the non-negative DNA concentration, the method used a dual track model for negative data processing operations.
    Type: Application
    Filed: June 25, 2024
    Publication date: January 23, 2025
    Inventors: Chengye Zou, Haifeng Li, Wenlong Wang
  • Publication number: 20240333602
    Abstract: Systems, apparatuses and methods include technology that identifies a model update that originates from a plurality of IoT devices. The technology determines votes from the plurality of IoT devices, where the votes indicate whether the model update will be deployed. The technology deploys the model update to the plurality of IoT devices based on the votes.
    Type: Application
    Filed: December 7, 2021
    Publication date: October 3, 2024
    Applicant: Intel Corporation
    Inventors: Hai Tao WANG, Yong LI, Kailun QIN, Chengye LI
  • Patent number: 11970523
    Abstract: The present invention discloses a polypeptide and application thereof. By modifying oxyntomodulin (OXM), hybridizing OXM with a peptide sequence of Exenatide, including enabling the polypeptide to be resistant to DPP-4 enzyme degradation through amino acid modification, and conjugating fatty acid chains at the same time, an OXM hybrid peptide having longer pharmacologic action time and better weight losing effects is obtained. Synthesis of a target polypeptide is fast realized by an orthogonal protection strategy solid-phase synthesis method, and a crude product is purified and freeze-dried to obtain the OXM hybrid peptide.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: April 30, 2024
    Assignee: CHINA PHARMACEUTICAL UNIVERSITY
    Inventors: Hai Qian, Wenlong Huang, Xingguang Cai, Chengye Li, Chunxia Liu, Yuxuan Dai
  • Publication number: 20220177537
    Abstract: The present invention discloses a polypeptide and application thereof. By modifying oxyntomodulin (OXM), hybridizing OXM with a peptide sequence of Exenatide, including enabling the polypeptide to be resistant to DPP-4 enzyme degradation through amino acid modification, and conjugating fatty acid chains at the same time, an OXM hybrid peptide having longer pharmacologic action time and better weight losing effects is obtained. Synthesis of a target polypeptide is fast realized by an orthogonal protection strategy solid-phase synthesis method, and a crude product is purified and freeze-dried to obtain the OXM hybrid peptide.
    Type: Application
    Filed: May 6, 2019
    Publication date: June 9, 2022
    Inventors: Hai QIAN, Wenlong HUANG, Xingguang CAI, Chengye LI, Chunxia LIU, Yuxuan DAI