Patents by Inventor Chengyuan Liang

Chengyuan Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-O-acetylbritannilatone spiro aryl isoxazoline compounds
    Patent number: 10618911
    Abstract: A compound of chemical formula I: or formula II: or a pharmaceutical acceptable salt thereof is disclosed. R1 is OH or OAc; X is C or N; and R2 is H, alkyl, alkoxy, benzyloxy, haloalkyl, OH, CN, NO2, or halogen, provided that when X is N, R2 is nil.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: April 14, 2020
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Han Li, Yuzhi Liu, Nan Qin, Juan Xia, Shaomeng Pei, Chengyuan Liang, Lei Tian
  • BERGENIN LIPOIC ACID ESTER WITH ANTIOXIDANT ACTIVITY AND A METHOD OF PREPARING THE SAME
    Publication number: 20190389876
    Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Application
    Filed: September 3, 2018
    Publication date: December 26, 2019
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Bin TIAN, Xingke JU, Lei TIAN, Jie LI, Songsong RUAN, Minyi JIA, Danni TIAN, Han LI, Qianqian ZHAO, Xuechuan WANG, Chengyuan LIANG
  • Bergenin lipoic acid ester with antioxidant activity and a method of preparing the same
    Patent number: 10494377
    Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: September 3, 2018
    Date of Patent: December 3, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Bin Tian, Xingke Ju, Lei Tian, Jie Li, Songsong Ruan, Minyi Jia, Danni Tian, Han Li, Qianqian Zhao, Xuechuan Wang, Chengyuan Liang
  • Bergenin thiodipropionic acid ester with antioxidant activity and a method of improving the antioxidant property of ganoderma lucidum spore oil using the same
    Patent number: 10487094
    Abstract: A compound having the following formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: September 3, 2018
    Date of Patent: November 26, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Yuzhi Liu, Danni Tian, Jie Li, Songsong Ruan, Han Li, Qianqian Zhao, Xuechuan Wang, Xeufeng Chen
  • Hydroxytyrosol p-phenylenedicarboxylate having antioxidant activity and a method of preparing the same
    Patent number: 10472321
    Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: July 13, 2019
    Date of Patent: November 12, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Yuzhi Liu, Xingke Ju, Yonghong Tang, Minghui Chang, Bin Tian, Dan Yang, Han Li, Ning Liu, Huayin Pu, Jian Cha, Juanna Song, Yongbo Wang
  • METHOD FOR PREPARING COLLAGEN AGGREGATE AND COLLAGEN FROM CHROMIUM-CONTAINING TANNED LEATHER WASTES BY COMBINED ACID-ENZYME CONTROLLED DEGRADATION TECHNOLOGY
    Publication number: 20190309051
    Abstract: A method for preparing a collagen from a chromium-containing tanned leather waste is disclosed. The method includes acid dechromation, obtaining a collagen aggregate, and converting the collagen aggregate to the collagen. The method also includes a reaction in a supercritical carbon dioxide reactor.
    Type: Application
    Filed: March 2, 2019
    Publication date: October 10, 2019
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Xuechuan WANG, Mengdi HOU, Xinhua LIU, Chengyuan LIANG, Ouyang YUE, Manhui ZHENG, Xing ZHU, Qingxin HAN, Ji LI, Huijie ZHANG, Taotao QIANG
  • Hydroxytyrosol isophorone diisocyannate derivative with antioxidant activity and a method of preparing the same
    Patent number: 10377702
    Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: August 13, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Yuzhi Liu, Xingke Ju, Yonghong Tang, Gennian Mao, Qianqian Zhao, Bin Tian, Jian Zha, Chunyang Shi, Yongbo Wang, Huayin Pu, Yanghan Liu
  • Hydroxytyrosol thiodipropionic acid ester with antioxidant activity and a method of preparing the same
    Patent number: 10343988
    Abstract: A compound having the following formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: July 9, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Lei Tian, Danni Tian, Yuzhi Liu, Xingke Ju, Nan Hui, Mi Wu, Juan Li, Han Li, Bin Tian, Qianqian Zhao
  • Gossypol eflornithine Schiff base compound with antitumor activities and a method of preparing the same
    Patent number: 10336689
    Abstract: A gossypol eflornithine Schiff base compound having the following Formula I: is disclosed. A method of preparing the compound of Formula I is also disclosed.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: July 2, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Shunjun Ding, Nan Hui, Juan Li, Dezhu Zhang, Xiaolin Xie
  • Hydroxytyrosol shikimic acid ester for treating cardiovascular deceases and a method of preparing the same
    Patent number: 10336682
    Abstract: A compound having the following formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: July 2, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Lei Tian, Yuzhi Liu, Xingke Ju, Nan Hui, Mi Wu, Juan Li, Han Li, Bin Tian, Qianqian Zhao, Gennian Mao, Nan Qin, Juan Xia, Zhenfeng Shi
  • Method of preparing 6-chloro-5-nitro-2,4-diaminopyrimidine and its application thereof
    Patent number: 10329261
    Abstract: A method of preparing 6-chloro-5-nitro-2,4-diaminopyrimidine includes: reacting guanidine hydrochloride with ethyl carbamoylacetate and sodium hypochlorite in the presence of a metal nitrate salt and acetate anhydride in an organic solvent.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: June 25, 2019
    Assignee: XI'AN TAIKOMED PHARMACEUTICAL TECHNOLOGY CO., LTD.
    Inventors: Yonghong Tang, Minghui Chang, Chengyuan Liang, Danni Tian, Juan Xia, Kaiqi Shi, Han Li, Xuechuan Wang
  • ALANTOLACTONE/ISOALANTOLACTONE SPIRO ARYL ISOXAZOLINE COMPOUNDS AND A METHOD OF USING THE SAME
    Publication number: 20190185487
    Abstract: A compound of chemical formula I: or chemical formula II: or a pharmaceutical acceptable salt thereof is disclosed. R1, R2, R3, and R4 are independently H, halogen, nitro, hydroxyl, cyano, benzyloxy, C1-C8 straight or branched alkyl, C1-C8 straight or branched haloalkyl, C1-C8 straight or branched alkoxy.
    Type: Application
    Filed: October 23, 2018
    Publication date: June 20, 2019
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan LIANG, Lei TIAN, Nan QIN, Juan XIA, Shaomeng PEI
  • 1-O-ACETYLBRITANNILATONE SPIRO ARYL ISOXAZOLINE COMPOUNDS AND A METHOD OF USING THE SAME
    Publication number: 20190185488
    Abstract: A compound of chemical formula I or a pharmaceutical acceptable salt thereof is disclosed. R1 is OH or OAc; X is C or N; and R2 is H, alkyl, alkoxy, benzyloxy, haloalkyl, OH, CN, NO2, or halogen, provided that when X is N, R2 is nil.
    Type: Application
    Filed: October 23, 2018
    Publication date: June 20, 2019
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan LIANG, Lei TIAN, Nan QIN, Juan XIA, Shaomeng PEI
  • 13-hydroxysparteine cinnamic acid derivatives with anti-tumor activities and a method of preparing the same
    Patent number: 10233183
    Abstract: A compound having the following formula I: In formula I, R1 and R2 are independently H, alkyl, alkoxy, and halogen. A method of preparing the compound of formula I is also disclosed.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: March 19, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Lei Tian, Yonghong Tang, Minghui Chang, Kaiqi Shi, Xingke Ju, Yuzhi Liu, Lili Wen, Han Li, Xuechuan Wang
  • Aesculin lipoic acid ester with antioxidant activity and a method of preparing the same
    Patent number: 10208077
    Abstract: A compound having the formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.
    Type: Grant
    Filed: August 11, 2018
    Date of Patent: February 19, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Taotao Qiang, Yunying Song, Longfang Ren, Xuechuang Wang, Chengyuan Liang, Lei Tian, Xinke Ju, Han Li, Qianqian Zhao
  • Aesculin thiodipropionic acid ester with antioxidant activity and a method of preparing the same
    Patent number: 10208078
    Abstract: A compound having the following formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.
    Type: Grant
    Filed: August 11, 2018
    Date of Patent: February 19, 2019
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Minyi Jia, Songsong Ruan, Jie Li, Lei Tian, Xinke Ju, Han Li, Qianqian Zhao, Xuechuang Wang
  • AESCULIN STURGEON SKIN GELATIN FILM WITH ANTIOXIDANT ACTIVITY AND ENTEROCOCCUS FAECALIS DETECTION ABILITY AND A METHOD OF PREPARING THE SAME
    Publication number: 20190031840
    Abstract: A method of preparing an aesculin sturgeon skin gelatin with antioxidant activity and Enterococcus faecalis detection ability includes: 1) mixing a sturgeon skin gelatin and distilled water in a ratio of 1:15-1:25 (w/v) at 50-70° C. and filtering to obtain a sturgeon skin gelatin solution; 2) adding aesculin and a glycerin solution to the sturgeon skin gelatin solution, stirring the resulted sturgeon skin gelatin solution at 30-50° C. for 30 minutes, and filtering; and 3) removing air bubbles from the sturgeon skin gelatin solution of step 2) under reduced pressure, placing the sturgeon skin gelatin solution on an acrylic glass, and drying the sturgeon skin gelatin solution at in a vented oven 25° C. and 45-55% relative humidity for 24 hours to obtain the aesculin sturgeon skin gelatin film.
    Type: Application
    Filed: July 3, 2018
    Publication date: January 31, 2019
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan LIANG, Lei TIAN, Minyi JIA, Ying HUANG, Xuechuan WANG, Taotao QIANG, Longfang REN, Xingke JU
  • Lappaconitine aza-cinnamic acid derivatives with anti-tumor activities and a method of preparing the same
    Patent number: 10100036
    Abstract: A lappaconitine aza-cinnamic acid derivative having the following formula (I): X is C or N, and R1, R2, and R3 are independently H or lower alkyl. A method of preparing the lappaconitine aza-cinnamic acid derivative of formula (I) is also disclosed.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: October 16, 2018
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Minyi Jia, Xingke Ju, Lei Tian, Danni Tian, Shunjun Ding
  • Isatin spiro compounds with antibacterial activities and a method of preparing the same
    Patent number: 10072020
    Abstract: An isatin spiro compound having the following formula (I): R1 is halogen or C1-3 alkyl; R2 is C1-3 alkyl or benzyl; and R3 and R3? are independently H, C1-3 alkyl or phenyl.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: September 11, 2018
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Danni Tian, Shunjun Ding
  • Hesperetin aza-cinnamic acid derivatives with anti-tumor activities and a method of preparing the same
    Patent number: 10059698
    Abstract: A hesperetin aza-cinnamic acid derivative has the following formula (I): R1 is H or alkyl, and R2 and R2 are independently H, alkyl, hydroxy, halogen, nitro, or alkoxy.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: August 28, 2018
    Assignee: Shaanxi University of Science and Technology
    Inventors: Chengyuan Liang, Minyi Jia, Yuecheng Lyu, Xingke Ju, Lei Tian