Patents by Inventor Chengzhong FAN

Chengzhong FAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of berberine or derivative thereof in preparing myocardial perfusion imaging agent
    Patent number: 11141496
    Abstract: Berberine or its derivatives are used in the preparation of myocardial perfusion imaging agents It has been verified using in vitro investigations, in vivo biodistribution, and small animal PET dynamic imaging, etc., that 18F-labeled berberine derivatives can specifically accumulate in cardiomyocytes or heart tissues, and has good distribution properties of targetting heart muscle in living animals, together with high contrast values of heart v.s. peripheral tissue (liver, lung, blood, muscle, bone, etc.).
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: October 12, 2021
    Assignee: WEST CHINA HOSPITAL, SICHUAN UNIVERSITY
    Inventors: Chengzhong Fan, Xiaoai Wu, Meng Liang, Xiaoli Mei, Tong Zhang, Rang Wang, Haotian Chen
  • USE OF BERBERINE OR DERIVATIVE THEREOF IN PREPARING MYOCARDIAL PERFUSION IMAGING AGENT
    Publication number: 20200330622
    Abstract: Berberine or its derivatives are used in the preparation of myocardial perfusion imaging agents It has been verified using in vitro investigations, in vivo biodistribution, and small animal PET dynamic imaging, etc., that 18F-labeled berberine derivatives can specifically accumulate in cardiomyocytes or heart tissues, and has good distribution properties of targetting heart muscle in living animals, together with high contrast values of heart v.s. peripheral tissue (liver, lung, blood, muscle, bone, etc.).
    Type: Application
    Filed: June 7, 2018
    Publication date: October 22, 2020
    Inventors: Chengzhong FAN, Xiaoai WU, Meng LIANG, Xiaoli MEI, Tong ZHANG, Rang WANG, Haotian CHEN