Abstract: The invention discloses an application method of medium and trace nutrient elements for wrapper hydroponic system. The application method includes the following steps: providing a nutrient solution cultivation system as well as medium and trace element nutrient solutions for facility-based cultivation of wrapper; the medium and trace element nutrient solutions are applied in the cultivation of wrapper; wherein the medium and trace element nutrient solutions contain modulated components, 65-420 ug/L boric acid and 230-1600 ug/L manganese salt, the modulated components contain at least two of 310-690 mg/L calcium salt, 400-1300 mg/L magnesium salt and 40-250 mg/L ferric salt. The present invention can obviously improve yield, appearance quality and leaf tensile force of the wrapper by applying the nutrient solution with specific components in different stage of the wrapper cultivation, respectively, thereby greatly improving the industrial availability of the wrapper raw materials.