Patents by Inventor Chenxi LIANG

Chenxi LIANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating metastasis with cathepsin C inhibitors
    Patent number: 12697328
    Abstract: Provided herein are methods for treating metastasis of a cancer with a pharmaceutical composition comprising an effective amount of a cathepsin C (CTSC) inhibitor. The CTSC inhibitor, in some embodiments, is a compound of Formula (I), or a pharmaceutically acceptable salt thereof, for example, brensocatib. The treatment methods inhibit, slow, or reverse the progression of the metastasis. In some embodiments, the methods further comprise reducing neutrophil infiltration and/or formation of neutrophil extracellular traps (NETs).
    Type: Grant
    Filed: September 10, 2021
    Date of Patent: August 4, 2026
    Assignee: SHANGHAI INSTITUTE OF NUTRITION AND HEALTH, CHINESE ACADEMY OF SCIENCES
    Inventors: Guohong Hu, Yansen Xiao, Min Cong, Chenxi Liang
  • Methods for Treating Metastasis with Cathepsin C Inhibitors
    Publication number: 20230321056
    Abstract: Provided herein are methods for treating metastasis of a cancer with a pharmaceutical composition comprising an effective amount of a cathepsin C (CTSC) inhibitor. The CTSC inhibitor, in some embodiments, is a compound of Formula (I), or a pharmaceutically acceptable salt thereof, for example, brensocatib. The treatment methods inhibit, slow, or reverse the progression of the metastasis. In some embodiments, the methods further comprise reducing neutrophil infiltration and/or formation of neutrophil extracellular traps (NETs).
    Type: Application
    Filed: September 10, 2021
    Publication date: October 12, 2023
    Inventors: Guohong HU, Yansen XIAO, Min CONG, Chenxi LIANG