Patents by Inventor Cheol-Heon Yea

Cheol-Heon Yea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL CHIP-BASED QUANTITATIVE ANALYSIS OF UNDIFFERENTIATED HUMAN PLURIPOTENT STEM CELL
    Publication number: 20180031513
    Abstract: The present invention relates to a method for detecting an undifferentiated pluripotent stem cell, and a cell-chip using the same. Since the cell chip-based quantitative analysis method of the present invention does not use antibodies, unlike flow cytometry or real-time PCR which has been conventionally used for the quantitative analysis of pluripotent stem cells, there is an advantage in that it is possible to conveniently and rapidly perform quantitative analysis, and since the function of cells is not affected even after analysis, it is possible to recover and use the cells used in the analysis.
    Type: Application
    Filed: July 21, 2015
    Publication date: February 1, 2018
    Applicant: SOGANG UNIVERSITY RESEARCH FOUNDATION
    Inventors: Hyuk Jin CHA, Jeong Woo CHOI, Cheol Heon YEA, Ho Chang JEONG
  • Sensor for detecting stem cell differentiation based on electrochemical methods
    Patent number: 9650663
    Abstract: This invention relates to a sensor for detecting a stem cell differentiation, including (a) an electrode; and (b) a substrate of an alkaline phosphatase. The phosphorylation or dephosphorylation of the substrate for an alkaline phosphatase as a stem cell undifferentiation marker which dephosphorylates its substrate may be measured using an electrical signal in the present sensor. Therefore, the sensor of the present invention enables to electrically detect a stem cell status in a high-throughput manner and to determine the stem cell differentiation.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: May 16, 2017
    Assignee: Industry-University Cooperation Foundation Sogang University
    Inventors: Jeong-Woo Choi, Cheol-Heon Yea
  • SENSOR FOR DETECTING STEM CELL DIFFERENTIATION BASED ON ELECTROCHEMICAL METHODS
    Publication number: 20140158554
    Abstract: This invention relates to a sensor for detecting a stem cell differentiation, including (a) an electrode; and (b) a substrate of an alkaline phosphatase. The phosphorylation or dephosphorylation of the substrate for an alkaline phosphatase as a stem cell undifferentiation marker which dephosphorylates its substrate may be measured using an electrical signal in the present sensor. Therefore, the sensor of the present invention enables to electrically detect a stem cell status in a high-throughput manner and to determine the stem cell differentiation.
    Type: Application
    Filed: November 27, 2013
    Publication date: June 12, 2014
    Applicant: Industry-University Cooperation Foundation Sogang University
    Inventors: Jeong-Woo Choi, Cheol-Heon Yea
  • SENSOR FOR DETECTING STEM CELL DIFFERENTIATION BASED ON ELECTROCHEMICAL METHODS
    Publication number: 20100243479
    Abstract: This invention relates to a sensor for detecting a stem cell differentiation, including (a) an electrode; and (b) a substrate of an alkaline phosphatase. The phosphorylation or dephosphorylation of the substrate for an alkaline phosphatase as a stem cell undifferentiation marker which dephosphorylates its substrate may be measured using an electrical signal in the present sensor. Therefore, the sensor of the present invention enables to electrically detect a stem cell status in a high-throughput manner and to determine the stem cell differentiation.
    Type: Application
    Filed: October 14, 2009
    Publication date: September 30, 2010
    Applicant: Industry-University Cooperation Foundation Sogang University
    Inventors: Jeong-Woo Choi, Cheol-Heon Yea