Abstract: A nutritional composition comprising the human milk oligosaccharides (HMOs) 2?-fucosyllactose (2FL), 3?-fucosyl-lactose (3FL), 3?-sialyllactose (3SL), and lacto-N-neotetraose (LNnT). The nutritional composition is useful for treating or preventing disorders associated with an above-normal number of granulocytes in a tissue. For example, the combinations may have utility in preventing or treating eosinophilic gastrointestinal diseases.

Abstract: A nutritional composition comprising the human milk oligosaccharides (HMOs) 2?-fucosyllactose (2FL), 3?-fucosyl-lactose (3FL), 3-sialyllactose (SSL), and lacto-N-neotetraose (LNnT). The nutritional composition is useful for inducing tolerance to an allergen, and/or speeding up outgrowth of an allergy, and/or treating or reducing the risk of an interleukin IL-10 mediated disease.

Abstract: The present invention provides compounds and compositions containing reduced nicotinamide riboside for use in methods of promoting protective immunity and/or for preventing and/or treating bacterial or viral infections and/or for limiting immune mediated pathology following infection in an individual comprising delivering to the individual in need an effective unit dose form of reduced nicotinamide.

Abstract: The present invention provides compounds and compositions containing reduced nicotinamide riboside for use in methods of prevention and/or treatment of lung disease and/or conditions. In one embodiment of the invention, said compounds and compositions of the invention improve the lung by maintaining or improving lung function. In another embodiment of the invention, the compounds and compositions of the invention improve lung recovery and regeneration after injury or surgery.