Patents by Inventor Cheryl A. Dyer

Cheryl A. Dyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reducing the reproductive capacity of mammals
    Patent number: 10646501
    Abstract: Provided are compositions and methods for reducing the reproductive capacity of mammals. The compositions and methods involve the use and administration of (a) a diterpenoid epoxide comprising a triptolide skeleton and which causes ovarian follicle depletion in female mammals and (b) an organic diepoxide which causes ovarian follicle depletion in female mammals.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: May 12, 2020
    Assignee: SENESTECH, INC.
    Inventors: Lorretta P. Mayer, Cheryl A. Dyer
  • REDUCING THE REPRODUCTIVE CAPACITY OF MAMMALS
    Publication number: 20180207181
    Abstract: Provided are compositions and methods for reducing the reproductive capacity of mammals. The compositions and methods involve the use and administration of (a) a diterpenoid epoxide comprising a triptolide skeleton and which causes ovarian follicle depletion in female mammals and (b) an organic diepoxide which causes ovarian follicle depletion in female mammals.
    Type: Application
    Filed: February 22, 2018
    Publication date: July 26, 2018
    Applicant: Senestech, Inc.
    Inventors: Lorretta P. MAYER, Cheryl A. Dyer
  • Reducing the reproductive capacity of mammals
    Patent number: 9956235
    Abstract: Provided are compositions and methods for reducing the reproductive capacity of mammals. The compositions and methods involve the use and administration of (a) a diterpenoid epoxide comprising a triptolide skeleton and which causes ovarian follicle depletion in female mammals and (b) an organic diepoxide which causes ovarian follicle depletion in female mammals.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: May 1, 2018
    Assignee: SENESTECH, INC.
    Inventors: Lorretta P. Mayer, Cheryl A. Dyer
  • REDUCING THE REPRODUCTIVE CAPACITY OF MAMMALS
    Publication number: 20150224124
    Abstract: Provided are compositions and methods for reducing the reproductive capacity of mammals. The compositions and methods involve the use and administration of (a) a diterpenoid epoxide comprising a triptolide skeleton and which causes ovarian follicle depletion in female mammals and (b) an organic diepoxide which causes ovarian follicle depletion in female mammals.
    Type: Application
    Filed: August 23, 2013
    Publication date: August 13, 2015
    Applicant: SENESTECH, INC.
    Inventors: Lorretta P. Mayer, Cheryl A. Dyer
  • Polypeptide analogs of apolipoprotein E, diagnostic systems and methods using the analogs
    Patent number: 5473039
    Abstract: The present invention contemplates a multimeric polypeptide capable of mimicking the ability of apo E to induce differentiated cellular function. The repeating unit of the polypeptide has an amino acid residue sequence corresponding to that represented by the formula LRXLRKRLLX. Also contemplated is a method for treating hypercholesterolemia in a patient, which method comprises administering to the patient an LDL plasma concentration-reducing amount of the polypeptide. Described as well, is the use of the polypeptide in preparing diagnostic antibodies, and their use in diagnostic systems and methods for detecting apo E antigens in vascular body fluids.
    Type: Grant
    Filed: December 9, 1991
    Date of Patent: December 5, 1995
    Assignee: The Scripps Research Institute
    Inventors: Cheryl A. Dyer, Linda K. Curtiss, Richard Smith
  • Polypeptide analogs of apolipoprotein E
    Patent number: 5182364
    Abstract: The present invention contemplates a method for treating hypercholesterolemia in a patient, which method comprises administering to the patient an LDL plasma concentration-reducing amount of a multimeric polypeptide capable of binding the LDL receptor. THe repeating unit of the polypeptide has an amino acid residue sequence corresponding to that represented by the formula LRKLRKRLLRDADDL.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: January 26, 1993
    Assignee: The Scripps Research Institute
    Inventors: Cheryl A. Dyer, Linda K. Curtiss, Richard Smith
  • Polypeptide analogs of Apolipoprotein E
    Patent number: 5177189
    Abstract: The present invention contemplates a multimeric polypeptide capable of mimicking the ability of Apo E in regulating lymphocyte proliferation and ovarian androgen synthesis.
    Type: Grant
    Filed: August 18, 1989
    Date of Patent: January 5, 1993
    Assignee: The Scripps Research Institute
    Inventors: Cheryl A. Dyer, Linda K. Curtiss, Richard Smith
  • Diagnostic systems and methods using polypeptide analogs of apolipoprotein E
    Patent number: 5168045
    Abstract: Apo E polypeptides capable of mimicking apolipoprotein E are described that are useful to prepare diagnostic antibodies, and for use in diagnostic systems and methods for detecting apo E antigens in vascular body fluids.
    Type: Grant
    Filed: June 18, 1990
    Date of Patent: December 1, 1992
    Assignee: The Scripps Research Institute
    Inventors: Cheryl A. Dyer, Linda K. Curtiss, Richard Smith