Patents by Inventor Cheryl Casper

Cheryl Casper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multifunctional and biologically active matrices from multicomponent polymeric solutions
    Patent number: 8338390
    Abstract: A functionalized electrospun matrix for the controlled-release of biologically active agents, such as growth factors, is presented. The functionalized matrix comprises a matrix polymer, a compatibilizing polymer and a biomolecule or other small functioning molecule. In certain aspects the electrospun polymer fibers comprise at least one biologically active molecule functionalized with low molecular weight heparin.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: December 25, 2012
    Assignee: University of Delaware
    Inventors: Kristi L. Kiick, Nori Yamaguchi, John Rabolt, Cheryl Casper
  • Multifunctional and Biologically Active Matrices from Multicomponent Polymeric Solutions
    Publication number: 20100297238
    Abstract: A functionalized electrospun matrix for the controlled-release of biologically active agents, such as growth factors, is presented. The functionalized matrix comprises a matrix polymer, a compatibilizing polymer and a biomolecule or other small functioning molecule. In certain aspects the electrospun polymer fibers comprise at least one biologically active molecule functionalized with low molecular weight heparin.
    Type: Application
    Filed: April 27, 2010
    Publication date: November 25, 2010
    Inventors: Kristi L. Kiick, Nori Yamaguchi, John Rabolt, Cheryl Casper
  • Multifunctional and biologically active matrices from multicomponent polymeric solutions
    Patent number: 7732427
    Abstract: The present invention relates to a biologically active functionalized electrospun matrix to permit immobilization and long-term delivery of biologically active agents. In particular the invention relates to a functionalized polymer matrix comprising a matrix polymer, a compatibilizing polymer and a biomolecule or other small functioning molecule. In certain aspects the electrospun polymer fibers comprise at least one biologically active molecule functionalized with low molecular weight heparin. Examples of active molecules that may be used with the multicomponent polymer of the invention include, for example, a drug, a biopolymer, for example a growth factor, a protein, a peptide, a nucleotide, a polysaccharide, a biological macromolecule or the like. The invention is further directed to the formation of functionalized crosslinked matrices, such as hydrogels, that include at least one functionalized compatibilizing polymer capable of assembly.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: June 8, 2010
    Assignee: University of Delaware
    Inventors: Kristi L. Kiick, Nori Yamaguchi, John Rabolt, Cheryl Casper
  • Multifunctional and biologically active matrices from multicomponent polymeric solutions
    Publication number: 20060240110
    Abstract: The present invention relates to a biologically active functionalized electrospun matrix to permit immobilization and long-term delivery of biologically active agents. In particular the invention relates to a functionalized polymer matrix comprising a matrix polymer, a compatibilizing polymer and a biomolecule or other small functioning molecule. In certain aspects the electrospun polymer fibers comprise at least one biologically active molecule functionalized with low molecular weight heparin. Examples of active molecules that may be used with the multicomponent polymer of the invention include, for example, a drug, a biopolymer, for example a growth factor, a protein, a peptide, a nucleotide, a polysaccharide, a biological macromolecule or the like. The invention is further directed to the formation of functionalized crosslinked matrices, such as hydrogels, that include at least one functionalized compatibilizing polymer capable of assembly.
    Type: Application
    Filed: March 31, 2006
    Publication date: October 26, 2006
    Inventors: Kristi Kiick, Nori Yamaguchi, John Rabolt, Cheryl Casper