Abstract: A mobile child-related facility includes a compartment having one or more access means to provide admission into the compartment. The compartment includes at least one child-friendly relieving area; at least one child-friendly utility space; and at least one vending station including a product vending machine for dispensing one or more products for consumption during child-related activities. The child-friendly relieving area, the child-friendly utility space, and the vending station are independent of each other and are accessible through the one or more access means.

Abstract: A nail polish removal device, especially an efficient toenail polish removal device from a user's feet, is disclosed. The device includes a housing with foot placement assembly having a first area and a second area adapted for receiving the toenails of both feet simultaneously. The device includes a reciprocating sponge assembly, coupled to the foot placement assembly such that the toenails are positioned in contact with the sponge assembly. The device further comprises a filler to receive nail polish removal fluid, which is in fluid communication with the reciprocating and rotating sponge assembly, via one or more tubes, to aid in the removal of nail polish from the toenails of the user's foot. The device further comprises a switch and other electronic components to actuate and reciprocate the sponge assembly, thereby enabling the user to remove the nail polish conveniently without scrubbing the nail polish manually.

Abstract: The invention pertains to methods of delivering a polypeptide to a cell comprising (a) contacting a cell with a replicon having a non-poliovirus nucleic acid substituted for a nucleic acid which encodes at least a portion of a protein necessary for encapsidation, the non-poliovirus nucleic acid encoding, in an expressible form, a polypeptide or fragment thereof; and (b) maintaining the cells under conditions appropriate for introduction of the replicons into the cells. The cell may be within a subject and the polypeptide may be a therapeutic agent. The methods of the invention may be used to treat diseases including central nervous system disorders, infectious diseases, and cancer.

Abstract: The invention pertains to methods of delivering a polypeptide to a cell comprising (a) contacting a cell with a replicon having a non-poliovirus nucleic acid substituted for a nucleic acid which encodes at least a portion of a protein necessary for encapsidation, the non-poliovirus nucleic acid encoding, in an expressible form, a polypeptide or fragment thereof; and (b) maintaining the cells under conditions appropriate for introduction of the replicons into the cells. The cell may be within a subject and the polypeptide may be a therapeutic agent. The methods of the invention may be used to treat diseases including central nervous system disorders, infectious diseases, and cancer.

Abstract: A variable sized diaper, which is reusable, is disclosed. The diaper inlcudes an outer liquid impermeable panel having a generally hourglass configuration. The outer panel is sealedly connected about its perimeter to a corresponding inner panel having a substantially identical outer perimeter. The inner panel includes a fluid absorbent core, longitudinally positioned along the length of the diaper which is circumscribed by a plurality of side panels and waist panels which are constructed of liquid impermeable fabric. A conjunction of the inner panel and the outer panel defines a liquid permeable absorbent core which is substantially surrounded by a fluid impermeable hollow pocket or sack which extends about the entire circumference of the absorbent core. A "V"-shaped pile attachment strip is positioned on the frontmost regions of the diaper and is adapted to connect with a pair of hook fasteners one of which is positioned on each of the two wing-like portions of the rear portion of the diaper.