Abstract: A novel, glass-ionomer cement (GIC), which is preferably bioactive, and which is both trivalent metal cation-free and magnesium-free, comprising: (i) a glass composition which is both trivalent metal cation-free and magnesium-free (and is preferably bioactive), and (ii) a polyacid.

Abstract: The invention provides a system and method for the automatic detection of items as originating from a specific source, e.g. client or customer, identifying specific characteristics of the items, comparing these characteristics to a database of sets of such characteristics identified with or more sources, and providing an output of items that match the characteristics. In one embodiment of the invention, a mailer detection and manifest system detects mail pieces that were sent by specific mailers using mail piece characteristics that are unique to the mail pieces of each mailers' job within a mixed mailer mail stream. This is preferably accomplished in real-time or near real-time while sorting the mail pieces after the mailers' specific mail piece characteristics have been determined.

Abstract: The invention relates to a method of treating at least one symptom of a lower urinary tract disorder in a subject in need of treatment wherein the symptom is selected from the group consisting of urinary frequency, urinary urgency, urinary urge incontinence, nocturia and enuresis. The method comprises administering to a subject in need of treatment a therapeutically effective amount of a compound that has 5-HT3 receptor antagonist activity and NorAdrenaline Reuptake Inhibitor (NARI) activity.

Abstract: The invention relates to a method of treating at least one symptom of a lower urinary tract disorder in a subject in need of treatment wherein the symptom is selected from the group consisting of urinary frequency, urinary urgency, urinary urge incontinence, nocturia and enuresis. The method comprises administering to a subject in need of treatment a therapeutically effective amount of a compound that has 5-HT3 receptor antagonist activity and NorAdrenaline Reuptake Inhibitor (NARI) activity.

Abstract: A sterilization pouch incorporates a selected bottom paper layer to which is bonded to a transparent resin top layer. The paper layer carries a printed self-sealed tape which is covered by a removable sterilization indicating strip. The pouch can be formed with two elongated spaced apart side seals which terminate in an end seal which is straight or chevron-shaped. Various peel designs can be incorporated.

Abstract: A cassette has a top joined with a releasably attached double hinge to a bottom. An interior region can be filled with dental/medical instruments for sterilization and/or storage. The instruments can be supported by pre-arranged supports and retaining members. A practitioner can configure the arrangement in the cassette in accordance with his/her preferences.

Abstract: The invention develops a weight management system which comprises administering tyrosine in the desired amount to change and maintain the body weight of an animal. If the animal is overweight, the animal would be fed a low level tyrosine food composition. If the animal is underweight, the animal would be fed a high level tyrosine food composition. The invention also relates to an low tyrosine animal food which contains, on dry matter basis: (a) from about 0.01% to less than about 0.4% of tyrosine, (b) from about 0.42% to about 3% of phenylalanine (c) from about 7% to about 70% of protein, (d) from about 1% to about 60% of fat, (e) from 0 to 90% of carbohydrate, (f) from 0 to about 40% of dietary fiber, and (g) from 0 to about 15% of nutritional balancing agents.

Abstract: This invention is directed generally to compositions (including foods, supplements, treats, toys, etc.) for animal consumption, particularly compositions that tend to aid in weight loss or reduction in weight gain, and particularly compositions that comprise one or more medium chain fatty acid triglycerides (“MCT”). This invention also is directed generally to methods for using such compositions. This invention is further directed generally to processes for making such compositions.

Abstract: This invention is directed generally to compositions (including foods, supplements, treats, toys, etc.) for animal consumption, particularly compositions that tend to aid in weight loss or reduction in weight gain, and particularly compositions that comprise oleamide. This invention also is directed generally to methods for using such compositions. This invention is further directed generally to processes for making such compositions.

Abstract: The invention relates to a method of treating at least one symptom of a lower urinary tract disorder in a subject in need of treatment wherein the symptom is selected from the group consisting of urinary frequency, urinary urgency, urinary urge incontinence, nocturia and enuresis. The method comprises administering to a subject in need of treatment a therapeutically effective amount of a compound that has 5-HT3 receptor antagonist activity and NorAdrenaline Reuptake Inhibitor (NARI) activity.

Abstract: The invention relates to a method of treating at least one symptom of a lower urinary tract disorder in a subject in need of treatment wherein the symptom is selected from the group consisting of urinary frequency, urinary urgency, urinary urge incontinence, nocturia and enuresis. The method comprises administering to a subject in need of treatment a therapeutically effective amount of a compound that has 5-HT3 receptor antagonist activity and NorAdrenaline Reuptake Inhibitor (NARI) activity.

Abstract: Micropatterned substrates and methods for fabrication of artificial nerve regeneration conduits and methods for regenerating nerves are provided. Guidance compounds or cells are seeded in grooves formed on the patterned substrate. The substrates may also be provided with electrodes to provide electrical guidance cues to the regenerating nerve. The micropatterned substrates give physical, chemical, cellular and/or electrical guidance cues to promote nerve regeneration at the cellular level.

Abstract: Micropatterned substrates and methods for fabrication of artificial nerve regeneration conduits and methods for regenerating nerves are provided. Guidance compounds or cells are seeded in grooves formed on the patterned substrate. The substrates may also be provided with electrodes to provide electrical guidance cues to the regenerating nerve. The micropatterned substrates give physical, chemical, cellular and/or electrical guidance cues to promote nerve regeneration at the cellular level.