Abstract: Various systems and methods are provided for injection training by collecting, processing, analyzing and displaying measured information associated with the delivery of an injection. The injection training systems can include an artificial training and certification head (TCH) with internal sensor and software, syringe(s) with one or more sensors and a wireless transmitter, a computer and/or tablet with image and other processors, and backend servers. Sensor-based measurements of a syringe's position and orientation in three-dimensional space relative to a training apparatus are obtained and processed to provide metrics of a trainee's injection performance. The system can provide one-target or two-target scoring injection training. The system can also provide training for multi-target scoring techniques, including but not limited to fanning, linear threading, cross hatching, serial puncture, serial threading, depot injection, Fern Pattern, cone, Z-Track method, and the like.