Patents by Inventor Cheryl Winkler

Cheryl Winkler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single nucleotide polymorphisms associated with renal disease
    Patent number: 9102983
    Abstract: Methods for determining the genetic predisposition of a human subject to developing renal disease, such as focal segmental glomerulosclerosis (FSGS) or end-stage kidney disease are provided herein. These methods include methods for detecting renal disease, or determining the risk of developing renal disease in a human subject, such as a subject of African ancestry. The methods utilize the detection of one or more haplotype blocks comprising at least two tag single nucleotide polymorphisms (SNPs) in a non-coding region of a MYH9 gene or detecting the presence of at least one tag SNP in a non-coding region of a MYH9 gene. An array for detecting a genetic predisposition to renal disease using probes complementary to the tag SNPs in the non-coding region of the MYH9 gene are also disclosed.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: August 11, 2015
    Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
    Inventors: Cheryl Winkler, George Nelson, Jeffrey B. Kopp, Michael W. Smith, Randall Johnson
  • SINGLE NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH RENAL DISEASE
    Publication number: 20100297660
    Abstract: Methods for determining the genetic predisposition of a human subject to developing renal disease, such as focal segmental glomerulosclerosis (FSGS) or end-stage kidney disease are provided herein. These methods include methods for detecting renal disease, or determining the risk of developing renal disease in a human subject, such as a subject of African ancestry. The methods utilize the detection of one or more haplotype blocks comprising at least two tag single nucleotide polymorphisms (SNPs) in a non-coding region of a MYH9 gene or detecting the presence of at least one tag SNP in a non-coding region of a MYH9 gene. An array for detecting a genetic predisposition to renal disease using probes complementary to the tag SNPs in the non-coding region of the MYH9 gene are also disclosed.
    Type: Application
    Filed: January 30, 2009
    Publication date: November 25, 2010
    Inventors: Cheryl Winkler, George Nelson, Jeffrey B. Kopp, Michael W. Smith, Randall Johnson