Patents by Inventor Chester A. Alper

Chester A. Alper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIAGNOSIS AND TREATMENT OF TYPE 1 DIABETES
    Publication number: 20090142355
    Abstract: Methods for the diagnosis and treatment of type 1 diabetes are described. HLA-DQA2 has now been identified as the gene which is primarily responsible for determining whether an individual is susceptible to develop type 1 diabetes. The use of HLA-DQA2 as a target for developing therapeutic and diagnostic targets for treating type 1 diabetes and detecting susceptibility for the disease is disclosed.
    Type: Application
    Filed: April 30, 2008
    Publication date: June 4, 2009
    Inventor: Chester A. Alper
  • Purification and uses of dendritic cells and monocytes
    Patent number: 7273753
    Abstract: Methods for the preparation of substantially purified populations of dendritic cells and monocytes from the peripheral blood of a mammal is described. Also described are vaccine compositions and methods for the treatment of certain diseases and medical conditions based on the substantially purified dendritic cells and monocytes.
    Type: Grant
    Filed: January 29, 2003
    Date of Patent: September 25, 2007
    Assignee: Center of Blood Research
    Inventors: Keith D. Crawford, Chester A. Alper
  • Purification and uses of dendritic cells and monocytes
    Publication number: 20040038398
    Abstract: Methods for the preparation of substantially purified populations of dendritic cells and monocytes from the peripheral blood of a mammal is described. Also described are vaccine compositions and methods for the treatment of certain diseases and medical conditions based on the substantially purified dendritic cells and monocytes.
    Type: Application
    Filed: January 29, 2003
    Publication date: February 26, 2004
    Inventors: Keith D. Crawford, Chester A. Alper
  • Enrichment of dendritic cells from blood
    Patent number: 6589526
    Abstract: A method for the enrichment of dendritic cells from the peripheral blood of a mammal is described. Peripheral blood having mononuclear cells from a mammal is provided. The mononuclear cells are separated from the peripheral blood. The mononuclear cells are separated into a first cell population having substantially lymphocytes and a second cell population having substantially myeloid cells. The myeloid cells are separated into a third cell population having substantially monocytes and a fourth cell population having substantially dendritic cells. Also described are purified dendritic cell populations, vaccine compositions and methods for the treatment of cancer using dendritic cells, and kits useful for the enrichment of dendritic cells from blood.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: July 8, 2003
    Assignee: Center for Blood Research
    Inventors: Keith D. Crawford, Chester A. Alper
  • Enrichment of dendritic cells form blood
    Publication number: 20010023072
    Abstract: A method for the enrichment of dendritic cells from the peripheral blood of a mammal is described. Peripheral blood having mononuclear cells from a mammal is provided. The mononuclear cells are separated from the peripheral blood. The mononuclear cells are separated into a first cell population having substantially lymphocytes and a second cell population having substantially myeloid cells. The myeloid cells are separated into a third cell population having substantially monocytes and a fourth cell population having substantially dendritic cells. Also described are purified dendritic cell populations, vaccine compositions and methods for the treatment of cancer using dendritic cells, and kits useful for the enrichment of dendritic cells from blood.
    Type: Application
    Filed: January 31, 2001
    Publication date: September 20, 2001
    Applicant: The Center For Blood Research, Inc.
    Inventors: Keith D. Crawford, Chester A. Alper
  • Enrichment of dendritic cells from blood
    Patent number: 6194204
    Abstract: A method for the enrichment of dendritic cells from the peripheral blood of a mammal is described. Peripheral blood having mononuclear cells from a mammal is provided. The mononuclear cells are separated from the peripheral blood. The mononuclear cells are separated into a first cell population having substantially lymphocytes and a second cell population having substantially myeloid cells. The myeloid cells are separated into a third cell population having substantially monocytes and a fourth cell population having substantially dendritic cells. Also described are purified dendritic cell populations, vaccine compositions and methods for the treatment of cancer using dendritic cells, and kits useful for the enrichment of dendritic cells from blood.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: February 27, 2001
    Assignee: Center for Blood Research, Inc.
    Inventors: Keith D. Crawford, Chester A. Alper