Abstract: Compounds of the formula ##STR1## and the pharmaceutically acceptable acid-addition salts thereof wherein R.sup.1 and R.sup.2 are hydrogen or alkyl of 1 to 4 carbons; R is hydrogen, alkyl of 1 to 4 carbons, alkanoyl of 2 to 5 carbons, or ##STR2## WHEREIN N IS 1, 2, OR 3; R.sup.3 is ##STR3## and X and X.sup.1 are hydrogen, halogen, alkyl of 1 to 4 carbons, alkoxy of 1 to 4 carbons, or trifluoromethyl are disclosed. These compounds are useful as central nervous system depressants and in particular as muscle relaxants.

Abstract: Compounds of the formula ##STR1## wherein R, X.sub.1, X.sub.2, A and B are as defined herein, and their N-oxides and acid addition salts thereof, are provided which have been found to possess anti-inflammatory activity. In addition, methods for preparing such compounds, pharmaceutical compositions containing such compounds, and methods for using such compositions as anti-inflammatory agents are also provided.

Abstract: Compounds of the following formula and their acid-addition and quaternary salts and N-oxides ##SPC1##Wherein X is hydrogen, chloro, fluoro, trifluoromethyl, lower alkyl, or lower alkoxy, R is hydrogen or lower alkyl, A is alkylene of 1 to 8 carbons, and B is --NH.sub.2, ##EQU1## wherein R.sup.1 is lower alkyl and R.sup.2 is phenyl or phenyl-lower alkyl are disclosed. These compounds are useful as central nervous system depressants.

Abstract: Compounds of the following formula and their acid addition and quaternary salts and N-oxides ##SPC1##Wherein X is hydrogen, chloro, fluoro, trifluoromethyl, lower alkyl, or lower alkoxy, R is hydrogen or lower alkyl, A is alkylene of 1 to 8 carbons, and B is --NH.sub.2, ##EQU1## wherein R.sup.1 is lower alkyl and R.sup.2 is phenyl or phenyl-lower alkyl are disclosed. These compounds are useful as central nervous system depressants.

Abstract: Benzothiazepines having the formula: ##SPC1##Wherein R.sub.1 is phenyl or substituted phenyl wherein the substituent is selected from the group consisting of alkyl, alkoxy, halogen, trifluoromethyl or alkyl ##EQU1## R.sub.2 is chlorine or bromine; and R.sub.5 is hydrogen, alkyl, alkoxy, halogen or trifluoromethyl; and wherein the terms alkyl and alkoxy, in each instance employed, refer to groups having 1 to 6 carbon atoms. These compounds are useful as intermediates in the preparation of the claimed pharmaceutically active compounds of Ser. No. 462,266, filed Apr. 19, 1974, now U.S. Pat. No. 3,895,006.

Abstract: Compounds of the formula ##SPC1##Their N-oxides and acid addition salts thereof are provided which have been found to possess anti-inflammatory activity. In addition, methods for preparing such compounds, pharmaceutical compositions containing such compounds, and methods for using such compositions as anti-inflammatory agents are also provided.