Abstract: Intravascular intervention catheters and catheters for performing an intravascular procedure that use a computer to control an operation at the end of the catheters are provided. The computer can process image data to determine where the important features are within a patient's vessels. The catheter can include imaging devices, steering devices, ablation mechanisms, or a combination thereof. By referencing the precisely-calculated location of the important features, the computer can provide signals that can be used by a control device (such as a set of servomotors for navigation) to operate the mechanisms at the catheter tip. Thus the catheter can be steered or an ablation mechanism can be operated or be prevented from operating depending on a detected location of the catheter.

Abstract: A steerable sheath for a catheter delivery system and associated devices and methods are disclosed. In some embodiments, the catheter delivery system includes a catheter sheath having a steerable distal portion and a flexible elongate member connecting to a steering unit. The flexible elongate member has a central lumen through which a therapeutic or diagnostic device of a first modality can be inserted, used to perform a procedure, and then removed and replaced by a different therapeutic or diagnostic device while the catheter sheath remains substantially at the same location within a patient.

Abstract: The invention provides devices and methods for crossing total chronic occlusions. In certain aspects, a device for imaging a vessel includes an elongate body defining a first lumen and comprising a distal end; a housing operably associated with the distal end and comprising a forward-looking imaging element; and a member at least partially disposed within the first lumen of the elongate body; the member configured to extend beyond the distal end of the elongate body to advance into an occluded vessel.

Abstract: A steerable sheath for a catheter delivery system and associated devices and methods are disclosed. In some embodiments, the catheter delivery system includes a catheter sheath having a steerable distal portion and a flexible elongate member connecting to a steering unit. The flexible elongate member has a central lumen through which a therapeutic or diagnostic device of a first modality can be inserted, used to perform a procedure, and then removed and replaced by a different therapeutic or diagnostic device while the catheter sheath remains substantially at the same location within a patient.

Abstract: The invention generally relates to intravascular intervention catheters and provides catheters for performing an intravascular procedure that use a computer to control an operation at the end of the catheter. The computer can process image data to determine where the important features are within a patient's vessels. The catheter can include imaging devices, steering devices, ablation mechanisms, or a combination thereof. By referencing the precisely-calculated location of the important features, the computer can provides signals that can be used by a control device (such as a set of servomotors for navigation) to operate the mechanisms at the catheter tip. Thus the catheter can be steered or an ablation mechanism can be operated or be prevented from operating depending on a detected location of the catheter.