Abstract: According to an embodiment, disclosed is a system comprising a processor wherein the processor is configured to receive an input data comprising an image of an ocular region of a user, clinical data of the user, and external factors; extract, using an image processing module comprising adaptive filtering techniques, ocular characteristics, combine, using a multimodal fusion module, the input data to determine a holistic health embedding; detect, based on a machine learning model and the holistic health embedding, a first output comprising likelihood of myopia, and severity of myopia; predict, based on the machine learning model and the holistic health embedding, a second output comprising an onset of myopia and a progression of myopia in the user; and wherein the machine learning model is a pre-trained model; and wherein the system is configured for myopia prognosis powered by multimodal data.