Patents by Inventor Chetan SRINATH

Chetan SRINATH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CARDIAC CELL REPROGRAMMING WITH MICRORNAS AND OTHER FACTORS
    Publication number: 20230137971
    Abstract: The present disclosure provides methods for generating induced cardiomyocytes by expression of selected microRNAs with MYOCD and ASCL1, or with MYOCD alone. Illustrative microRNAs include miR-133, miR-1, miR-19, and/or miR-20b. The present disclosure further provides gene-delivery vectors comprising one or more polynucleotides encoding a selected microRNA with YOCD, withMYOCD and ASCL1, with MYOCD-2A-ASCL1, or with ASCL1-2A-MYOCD. It further provides methods of using such compositions and vectors, or induced cardiomyocytes generated with these factors, for treating a heart condition.
    Type: Application
    Filed: July 10, 2020
    Publication date: May 4, 2023
    Inventors: Huanyu ZHOU, Chetan SRINATH, Timothy HOEY