Patents by Inventor Cheung Hoi Yu
Cheung Hoi Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230366881Abstract: The application relates to a method and device for quantitatively analyzing the detection results of lateral flow-type test kits. Disclosed is a method for quantitatively analyzing the test results of a lateral flow-type test kit wherein the test kit includes a result area in which a control C-line region and a detection T-line region are set.Type: ApplicationFiled: March 29, 2023Publication date: November 16, 2023Inventors: Cheung Hoi Yu, Shui Ying Tsang, Wing Cheong Chan
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Patent number: 11262327Abstract: Methods for fabricating a biochip for detecting or sequencing biomolecules are shown. Such a biochip may for instance include: a base member; a dielectric layer deposited on the base member and having at least two rows of discrete recesses formed thereon; and two or more electrodes sandwiched between the base member and the dielectric layer and running under respective row of discrete recesses, the two or more electrodes separated from each other along lengths thereof by a portion of the dielectric layer; wherein the dielectric layer defines a continuous operation surface above the electrodes and on which the discrete recesses are deposited for detecting or sequencing of biomolecules, when an electric field is applied through the electrodes, a field gradient is created to draw a biomolecule towards a preferred part of the operation surface.Type: GrantFiled: June 20, 2019Date of Patent: March 1, 2022Assignee: Hai Kang Life Corporation LimitedInventors: Cheung Hoi Yu, Bo Liang Jia, Cheng Chang Lai
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Publication number: 20190302094Abstract: Methods for fabricating a biochip for detecting or sequencing biomolecules are shown. Such a biochip may for instance include: a base member; a dielectric layer deposited on the base member and having at least two rows of discrete recesses formed thereon; and two or more electrodes sandwiched between the base member and the dielectric layer and running under respective row of discrete recesses, the two or more electrodes separated from each other along lengths thereof by a portion of the dielectric layer; wherein the dielectric layer defines a continuous operation surface above the electrodes and on which the discrete recesses are deposited for detecting or sequencing of biomolecules, when an electric field is applied through the electrodes, a field gradient is created to draw a biomolecule towards a preferred part of the operation surface.Type: ApplicationFiled: June 20, 2019Publication date: October 3, 2019Inventors: Cheung Hoi Yu, Bo Liang Jia, Cheng Chang Lai
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Patent number: 10379101Abstract: A biochip for detecting or sequencing biomolecules and a method of making the same. The biochip comprises a base member; a dielectric layer being deposited on the base member and having at least two rows of discrete recesses being formed thereon; and two or more electrodes being sandwiched between the base member and the dielectric layer and running under respective row of discrete recesses, the two or more electrodes are separated from each other along length by a portion of the dielectric layer; wherein the dielectric layer defines a continuous operation surface above the electrodes and on which the discrete recesses are deposited for detecting or sequencing of biomolecules, when an electric field is applied through the electrodes, a field gradient is created to draw biomolecule towards a preferred part of the operation surface.Type: GrantFiled: November 23, 2015Date of Patent: August 13, 2019Assignee: HAI KANG LIFE CORPORATION LIMITEDInventors: Cheung Hoi Yu, Bo Liang Jia, Cheng Chang Lai
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Publication number: 20170146509Abstract: A biochip for detecting or sequencing biomolecules and a method of making the same. The biochip comprises a base member; a dielectric layer being deposited on the base member and having at least two rows of discrete recesses being formed thereon; and two or more electrodes being sandwiched between the base member and the dielectric layer and running under respective row of discrete recesses, the two or more electrodes are separated from each other along length by a portion of the dielectric layer; wherein the dielectric layer defines a continuous operation surface above the electrodes and on which the discrete recesses are deposited for detecting or sequencing of biomolecules, when an electric field is applied through the electrodes, a field gradient is created to draw biomolecule towards a preferred part of the operation surface.Type: ApplicationFiled: November 23, 2015Publication date: May 25, 2017Inventors: Cheung Hoi YU, Bo Liang JIA, Cheng Chang LAI
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Patent number: 8198070Abstract: Apparatus and methods are described for detecting target DNA in a biological sample using capture probes and electrically-assisted hybridization. The reaction cell is formed with an attachment surface of aluminum oxide for better thermal and physical properties, and the aluminum oxide surface is coated with anti-DIG antibody to provide a convenient attachment layer for the capture probes allowing their correct orientation, while the capture probes are formed with a DIG-label so that they attach to the surface of the cell through an anti-DIG/DIG linkage.Type: GrantFiled: May 24, 2010Date of Patent: June 12, 2012Assignee: Hai Kang Life Corporation LimitedInventors: Cheung Hoi Yu, Lok-Ting Lau, Selma Sau Wah Lin, Duncan Ka-Yun Chan
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Patent number: 8110669Abstract: Apparatus and methods are described for detecting target DNA in a biological sample using capture probes and electrically-assisted hybridization. The reaction cell is formed with an attachment surface of aluminum oxide for better thermal and physical properties, and the aluminum oxide surface is coated with anti-DIG antibody to provide a convenient attachment layer for the capture probes allowing their correct orientation, while the capture probes are formed with a DIG-label so that they attach to the surface of the cell through an anti-DIG/DIG linkage.Type: GrantFiled: March 16, 2011Date of Patent: February 7, 2012Assignee: Hai Kang Life Corporation LimitedInventors: Cheung Hoi Yu, Lok-Ting Lau, Selma Sau Wah Lin, Duncan Ka-Yun Chan
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Publication number: 20120010093Abstract: There are disclosed apparatus and methods for the field-assisted acceleration of biological processes involving charged entities, including in particular the detection of target DNA in a biological sample. A reaction cell is provided with a dielectric surface, and a field is generated by inducing charge-separation in the dielectric material by applying a potential to an electrode in contact with the dielectric material.Type: ApplicationFiled: February 14, 2011Publication date: January 12, 2012Applicant: HAI KANG LIFE CORPORATION LIMITEDInventors: Cheung Hoi Yu, Lok Ting Lau, Ka Wai Wong
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Publication number: 20110165665Abstract: Apparatus and methods are described for detecting target DNA in a biological sample using capture probes and electrically-assisted hybridization. The reaction cell is formed with an attachment surface of aluminum oxide for better thermal and physical properties, and the aluminum oxide surface is coated with anti-DIG antibody to provide a convenient attachment layer for the capture probes allowing their correct orientation, while the capture probes are formed with a DIG-label so that they attach to the surface of the cell through an anti-DIG/DIG linkage.Type: ApplicationFiled: March 16, 2011Publication date: July 7, 2011Applicant: HAI KANG LIFE CORPORATION LIMITEDInventors: Cheung Hoi YU, Lok-Ting Lau, Selma Sau Wah Lin, Duncan Ka-Yun Chan
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Patent number: 7888109Abstract: There are disclosed apparatus and methods for the field-assisted acceleration of biological processes involving charged entities, including in particular the detection of target DNA in a biological sample. A reaction cell is provided with a dielectric surface, and a field is generated by inducing charge-separation in the dielectric material by applying a potential to an electrode in contact with the dielectric material.Type: GrantFiled: May 1, 2008Date of Patent: February 15, 2011Assignee: Hai Kang Life Corporation LimitedInventors: Cheung Hoi Yu, Lok Ting Lau, Ka Wai Wong
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Publication number: 20100233721Abstract: Apparatus and methods are described for detecting target DNA in a biological sample using capture probes and electrically-assisted hybridization. The reaction cell is formed with an attachment surface of aluminum oxide for better thermal and physical properties, and the aluminum oxide surface is coated with anti-DIG antibody to provide a convenient attachment layer for the capture probes allowing their correct orientation, while the capture probes are formed with a DIG-label so that they attach to the surface of the cell through an anti-DIG/DIG linkage.Type: ApplicationFiled: May 24, 2010Publication date: September 16, 2010Applicant: HAI KANG LIFE CORPORATION LIMITEDInventors: Cheung Hoi Yu, Lok-Ting Lau, Selma Sau Wah Lin, Duncan Ka-Yun Chan
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Patent number: 7749705Abstract: Apparatus and methods are described for detecting target DNA in a biological sample using capture probes and electrically-assisted hybridization. The reaction cell is formed with an attachment surface of aluminum oxide for better thermal and physical properties, and the aluminum oxide surface is coated with anti-DIG antibody to provide a convenient attachment layer for the capture probes allowing their correct orientation, while the capture probes are formed with a DIG-label so that they attach to the surface of the cell through an anti-DIG/DIG linkage.Type: GrantFiled: November 15, 2006Date of Patent: July 6, 2010Assignee: Hai Kang Life Corporation LimitedInventors: Cheung Hoi Yu, Lok-Ting Lau, Selma Sau Wah Lin, Duncan Ka-Yun Chan
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Publication number: 20100112548Abstract: Current methods for detecting influenza A subtype H5 virus, for example cell culture, haemagglutination-inhibition, fluorescent antibody and enzyme immunoassay, and reverse transcriptase polymerase chain reaction (RT-PCR) may have the disadvantages of low sensitivity and low specificity. Furthermore, such methods are relatively difficult to use, and may not be suitable for routine detection on a daily basis. The kit for detecting H5 virus of this invention may provide a user-friendly alternative that is relatively more sensitive and specific to H5 virus. The detection kit utilizes two specially designed primers A and B for the replication of H5 virus, and a specific capture probe for immobilizing the amplified viral RNA. An additional primer C is also designed for the detection of pathogenic H5 virus. The detection of H5 virus by the detection kit may be accomplished within one day if desired.Type: ApplicationFiled: October 5, 2009Publication date: May 6, 2010Applicant: Hai Kang Life Corporation LimitedInventors: Albert Cheung-Hoi YU, Ka-Lun So, Lung-Sang Ko, Lok-Ting Lau
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Patent number: 7611837Abstract: Current methods for detecting influenza A subtype H5 virus, for example cell culture, haemagglutination-inhibition, fluorescent antibody and enzyme immunoassay, and reverse transcriptase polymerase chain reaction (RT-PCR) may have the disadvantages of low sensitivity and low specificity. Furthermore, such methods are relatively difficult to use, and may not be suitable for routine detection on a daily basis. The kit for detecting H5 virus of this invention may provide a user-friendly alternative that is relatively more sensitive and specific to H5 virus. The detection kit utilizes two specially designed primers A and B for the replication of H5 virus, and a specific capture probe for immobilizing the amplified viral RNA. An additional primer C is also designed for the detection of pathogenic H5 virus. The detection of H5 virus by the detection kit may be accomplished within one day if desired.Type: GrantFiled: September 27, 2001Date of Patent: November 3, 2009Assignee: Hai Kang Life Corporation Ltd.Inventors: Albert Cheung-Hoi Yu, Ka-Lun So, Lung-Sang Ko, Lok-Ting Lau
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Publication number: 20080242562Abstract: There are disclosed apparatus and methods for the field-assisted acceleration of biological processes involving charged entities, including in particular the detection of target DNA in a biological sample. A reaction cell is provided with a dielectric surface, and a field is generated by inducing charge-separation in the dielectric material by applying a potential to an electrode in contact with the dielectric material.Type: ApplicationFiled: May 1, 2008Publication date: October 2, 2008Applicant: HAI KANG LIFE CORPORATION LIMITEDInventors: Cheung Hoi YU, Lok Ting Lau, Ka Wai Wong
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Patent number: 7390622Abstract: There are disclosed apparatus and methods for the field-assisted acceleration of biological processes involving charged entities, including in particular the detection of target DNA in a biological sample. A reaction cell is provided with a dielectric surface, and a field is generated by inducing charge-separation in the dielectric material by applying a potential to an electrode in contact with the dielectric material.Type: GrantFiled: October 16, 2003Date of Patent: June 24, 2008Assignee: Hai Kang Life Corporation LimitedInventors: Cheung Hoi Yu, Lok Ting Lau, Ka Wai Wong
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Publication number: 20080090224Abstract: The present invention relates to a process for the detection of nucleic acids from biological or environmental samples. The technique involves the amplification of the nucleic acid of interest, after conversion to cDNA if necessary, after which the amplified nucleic acid is used as the template for further amplification by the real-time PCR (RT-PCR) technique. This combination of amplification procedures increases the sensitivity and specificity of the amplification compared with conventional amplification techniques. The invention also relates to primers for the use in this method and a diagnostic test kit.Type: ApplicationFiled: April 30, 2004Publication date: April 17, 2008Applicants: HONG KONG DNA CHIPS LIMITED, HAI KANG LIFE CORPORATION LIMITEDInventors: Cheung Hoi Yu, Lok Ting Lau
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Patent number: 7153687Abstract: Apparatus and methods are described for detecting target DNA in a biological sample using capture probes and electrically-assisted hybridization. The reaction cell is formed with an attachment surface of aluminum oxide for better thermal and physical properties, and the aluminum oxide surface is coated with anti-DIG antibody to provide a convenient attachment layer for the capture probes allowing their correct orientation, while the capture probes are formed with a DIG-label so that they attach to the surface of the cell through an anti-DIG/DIG linkage.Type: GrantFiled: August 13, 2002Date of Patent: December 26, 2006Assignee: Hong Kong DNA Chips LimitedInventors: Cheung Hoi Yu, Lok-Ting Lau, Selma Sau Wah Lin, Duncan Ka-Yun Chan
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Publication number: 20040142319Abstract: Current methods for detecting influenza A subtype H5 virus, for example cell culture, haemagglutination-inhibition, fluorescent antibody and enzyme immunoassay, and reverse transcriptase polymerase chain reaction (RT-PCR) may have the disadvantages of low sensitivity and low specificity. Furthermore, such methods are relatively difficult to use, and may not be suitable for routine detection on a daily basis. The kit for detecting H5 virus of this invention may provide a user-friendly alternative that is relatively more sensitive and specific to H5 virus. The detection kit utilizes two specially designed primers A and B for the replication of H5 virus, and a specific capture probe for immobilizing the amplified viral RNA. An additional primer C is also designed for the detection of pathogenic H5 virus. The detection of H5 virus by the detection kit may be accomplished within one day if desired.Type: ApplicationFiled: April 7, 2003Publication date: July 22, 2004Inventors: Albert Cheung-Hoi Yu, Ka-Lun So, Lung-Sang Ko, Lok-Ting Lau
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Publication number: 20040033496Abstract: Apparatus and methods are described for detecting target DNA in a biological sample using capture probes and electrically-assisted hybridization. The reaction cell is formed with an attachment surface of aluminum oxide for better thermal and physical properties, and the aluminum oxide surface is coated with anti-DIG antibody to provide a convenient attachment layer for the capture probes allowing their correct orientation, while the capture probes are formed with a DIG-label so that they attach to the surface of the cell through an anti-DIG/DIG linkage.Type: ApplicationFiled: August 13, 2002Publication date: February 19, 2004Inventors: Cheung Hoi Yu, Lok-Ting Lau, Selma Sau Wah Lin, Duncan Ka-Yun Cha