Abstract: The present invention provides a catheter for treating occlusions in blood vessels. An exemplary catheter for treating occlusions in blood vessels comprises a tubular inner member including a base segment with a first lumen defining a fluid inlet port, and a second lumen defining a fluid outlet port. An extension segment is distal to the base segment. The extension segment has a reduced cross-section. An emitter assembly includes a first insulated wire extending through the second lumen and a second insulated wire, and a conductive sheath wrapped circumferentially around the first insulated wire, the second insulated wire, and the extension segment. A cap or balloon is sealably attached to the distal end of the catheter and surrounds the emitter assembly, said cap or balloon being fillable with conductive fluid.

Abstract: The present invention relates to methods of treating patients with primary immunodeficiency diseases and disorders, using a CXCR4 inhibitor.

Abstract: The invention is a composition of human insulin or insulin analog that includes specific concentrations of citrate, chloride, in some cases including the addition of sodium chloride, zinc and, optionally, magnesium chloride and/or surfactant, and that has faster pharmacokinetic and/or pharmacodynamic action than commercial formulations of existing insulin analog products.

Abstract: The invention is a composition of human insulin or insulin analog that includes specific concentrations of citrate, chloride, in some cases including the addition of sodium chloride, zinc and, optionally, magnesium chloride and/or surfactant, and that has faster pharmacokinetic and/or pharmacodynamic action than commercial formulations of existing insulin analog products.

Abstract: A weight plate has an integrally molded center plate including a centrally located bore disposed in the center with an elongated first hand grip and an elongated second hand grip diametrically opposed to each other toward the opposite sides of the center plate. The first hand and second hand grips may have circular cross-sections. The first hand and second hand grip may include an interior perimeter and an exterior perimeter in spaced relation to each other, through which an opening is formed between the interior and exterior perimeter of the center plate so that the fingers and thumb of a user’s hand can be disposed through the opening for sufficient gripping of the weight plate. A mounting member can be passed through the bore for some particular exercises. With many different ways of using, the weight plate is compatible with a number of varied exercises and movements for an individual.

Abstract: An offshore facility for producing a liquefied natural gas using an associated gas includes a crude oil production offshore facility having a crude oil processing device for refining crude oil collected from a subsea well to produce oil, and a gas reinjection device for compressing an associated gas separated in crude oil refining process to be reinjected into a reservoir, and a liquefied natural gas production offshore facility supplied with a feed gas including at least a part of the associated gas from the crude oil production offshore facility, and processing and liquefying the feed gas to generate a liquefied natural gas. The crude oil production offshore facility includes a feed gas supply unit for recovering a back-flow gas formed when an injection gas compressed by the gas reinjection device flows backward and generating the feed gas by using the back-flow gas.

Abstract: The invention is a composition of human insulin or insulin analog that includes specific concentrations of citrate, chloride, in some cases including the addition of sodium chloride, zinc and, optionally, magnesium chloride and/or surfactant, and that has faster pharmacokinetic and/or pharmacodynamic action than commercial formulations of existing insulin analog products.

Abstract: A controller for controlling the display of secondary digital content displayed in an overlay above a primary video stream. The controller includes a touch interface device, a processor, and a memory storing non-transitory instructions. These instructions, when executed, can include (i) detecting a first input gesture by a user on the touch interface device, (ii) in response to detecting the first input gesture, selecting an application for display, (iii) detecting a second input gesture by the user on the touch interface device, (iv) in response to detecting the second input gesture, scrolling through a currently-displayed layer of the selected application displayed, (v) detecting a third input gesture by the user on the touch interface device, and (vi) in response to detecting the third input gesture, scrolling between layers of the selected application in a simulated Z-space.

Abstract: The invention is a composition of human insulin or insulin analog that includes specific concentrations of citrate, chloride, in some cases including the addition of sodium chloride, zinc and, optionally, magnesium chloride and/or surfactant, and that has faster pharmacokinetic and/or pharmacodynamic action than commercial formulations of existing insulin analog products.

Abstract: Disclosed is a mutant strain of Sarcocystidae in which the two genes mic1 and mic3 are deleted containing two specific recombination sites of an enzyme allowing a specific recombination, in particular Cre-recombinase, the specific recombination sites being at the respective locus of each of the deleted genes, the specific recombination site of the enzyme allowing specific recombination, in particular of the Cre-recombinase, at the locus of the deleted mic1 gene being different from that of the deleted mic3 gene.

Abstract: A calling user initiates a telephonic communication with a receiving user by dialing a phone number of the receiving user in his or her address book. The communication is transmitted from the calling user's device to the receiving user's device through a network that is not using Internet protocol or Internet-based, e.g., Transmission Control Protocol (TCP), Internet Protocol (IP), TCP-IP, or Voice over Internet Protocol (VoIP). After a number of notifications has passed on the receiving user's device and the receiving user is not able to answer the telephonic communication, a local voicemail recorder will be activated to record and store the telephonic communication for later retrieval by the receiving user. The stored communication is identifier by a sequence of string containing at least one of a name, a telephone number, a storage location, a date-time attribute, and a duration associated with the stored communication.

Abstract: A controller for controlling the display of secondary digital content displayed in an overlay above a primary video stream. The controller includes a touch interface device, a processor, and a memory storing non-transitory instructions. These instructions, when executed, can include (i) detecting a first input gesture by a user on the touch interface device, (ii) in response to detecting the first input gesture, selecting an application for display, (iii) detecting a second input gesture by the user on the touch interface device, (iv) in response to detecting the second input gesture, scrolling through a currently-displayed layer of the selected application displayed, (v) detecting a third input gesture by the user on the touch interface device, and (vi) in response to detecting the third input gesture, scrolling between layers of the selected application in a simulated Z-space.

Abstract: Disease subtyping is accomplished by a computer-implemented algorithm that manipulates a first genetic dataset to construct a set of first connectivity matrices. To this set of matrices Gaussian noise is introduced to generate a perturbed dataset. The computer-implemented algorithm assesses which of the set of first connectivity matrices was least affected by introduction of noise and that matric is used to define the optimal clustering. Once the optimal clustering is determined, computer-implemented supervised classification is performed to determine, for a particular patient, with which disease subtype cluster that person's genetic data most closely aligns. Armed with this knowledge, the treatment regimen is specified with much higher likelihood of success.

Abstract: An offshore facility for producing a liquefied natural gas using an associated gas includes a crude oil production offshore facility having a crude oil processing device for refining crude oil collected from a subsea well to produce oil, and a gas reinjection device for compressing an associated gas separated in crude oil refining process to be reinjected into a reservoir, and a liquefied natural gas production offshore facility supplied with a feed gas including at least a part of the associated gas from the crude oil production offshore facility, and processing and liquefying the feed gas to generate a liquefied natural gas. The crude oil production offshore facility includes a feed gas supply unit for recovering a back-flow gas formed when an injection gas compressed by the gas reinjection device flows backward and generating the feed gas by using the back-flow gas.

Abstract: A controller for controlling the display of secondary digital content displayed in an overlay above a primary video stream. The controller includes a touch interface device, a processor, and a memory storing non-transitory instructions. These instructions, when executed, can include (i) detecting a first input gesture by a user on the touch interface device, (ii) in response to detecting the first input gesture, selecting an application for display, (iii) detecting a second input gesture by the user on the touch interface device, (iv) in response to detecting the second input gesture, scrolling through a currently-displayed layer of the selected application displayed, (v) detecting a third input gesture by the user on the touch interface device, and (vi) in response to detecting the third input gesture, scrolling between layers of the selected application in a simulated Z-space.