Abstract: The present invention provides antibody or the antigen-binding portion thereof bind to carbohydrate antigen, such as Globo series antigens (e.g. Globo H, SSEA-4 or SSEA-3). Also disclosed herein are pharmaceutical compositions and methods for the inhibition of cancer cells in a subject in need thereof. The pharmaceutical compositions comprise an antibody or an antigen-binding portion thereof and at least one pharmaceutically acceptable carrier.

Abstract: A method and device that interrogates the availability of a called party before placing a communication from the calling party to the called party. A callback may be initiated so that both communications are completed simultaneously. The routing of communication may take place through any one of a number of different networks and at another time of the day, even if the caller does not otherwise have access to those networks.

Abstract: A computing platform for facilitating dynamic connection and collaboration of service providers and service requesters to transact services in a secure computing environment. The environment includes data content comprising emails, messages, biographical information and human resources related data associated with the users. The platform includes a connection module for connecting users to form groups, and a collaboration module for creating a virtual secure data room for collaboration and sharing of encrypted data by the connected users in a user-friendly and transparent manner. The platform further comprises an indexing and parsing module for identifying keywords and topics in the data content associated with the users and a matching module for matching project requirements of service requesters to profiles of the service requesters, the profiles including the parsed data content of the users.

Abstract: The present invention provides for bidirectional or duplex transmission of multimedia content such as live video and/or audio between access devices of a calling party and a called party in a convergent network. The quality of transmission is managed through a convergent communications platform, which periodically tests performance characteristics of network routes in operative communication with the platform, categorizes the network routes based on measured performance metrics, and selects network operators whose network characteristics meet the desired duality parameters of a particular multimedia content to be transmitted (e.g., real time high definition video conference). The management of transmissions is transparent to the end users who will be able to communicate with others regardless of the type of devices or networks the caked parties use or subscribe to.

Abstract: A computing platform for facilitating dynamic connection and collaboration of users to transact services in a secure computing environment. The users include service providers and service requesters. The platform includes a registration module for registering users including service requesters and service providers, a connection module for connect users to form groups based on users' selective invitations to other users, and a collaboration module for creating a virtual secure data room for collaboration and sharing of encrypted data by the connected users in a user-friendly and transparent manner. The platform further comprises a transaction module for settling payments between the service requesters and the service providers based on completion of previously agreed project milestones.

Abstract: A method and device that interrogates the availability of a called party before placing a communication from the calling party to the called party. A callback may be initiated so that both communications are completed simultaneously. The routing of communication may take place through any one of a number of different networks and at another time of the day, even if the caller does not otherwise have access to those networks.

Abstract: A computing platform for facilitating dynamic connection and collaboration of users to transact services in a secure computing environment. The users include service providers and service requesters. The platform includes a registration module for registering users including service requesters and service providers, a connection module for connect users to form groups based on users' selective invitations to other users, and a collaboration module for creating a virtual secure data room for collaboration and sharing of encrypted data by the connected users in a user-friendly and transparent manner. The platform further comprises a transaction module for settling payments between the service requesters and the service providers based on completion of previously agreed project milestones.

Abstract: The present invention provides for bidirectional or duplex transmission of multimedia content such as live video and/or audio between access devices of a calling party and a called party in a convergent network. The quality of transmission is managed through a convergent communications platform, which periodically tests performance characteristics of network routes in operative communication with the platform, categorizes the network routes based on measured performance metrics, and selects network operators whose network characteristics meet the desired quality parameters of a particular multimedia content to be transmitted (e.g., real-time high definition video conference). The management of transmissions is transparent to the end users who will be able to communicate with others regardless of the type of devices or networks the called parties use or subscribe to.

Abstract: A method of settling accounts of buyers and sellers of telecommunication services by an online exchange system includes storing data representing a financial account of at least one seller and at least one buyer, wherein the financial account includes at least one of accounts receivable and cash receipts. A service node receives an offer to sell the services from the at least one seller and requests to buy the services from the at least one buyer. The service node then matches the offers and requests in accordance with one or more parameters specified in the offers and requests. A route table is generated based on the routes specified in the matched offers and requests and a switch node is configured based on the route table. Fees are computed based on the usage of the matched routes and the financial accounts of the at least one seller and at least one buyer based on the computed fees.

Abstract: A method for facilitating the trading of media space includes collecting, by a server node, an offer of an ad avail from a seller and a request for an ad avail by a buyer. The offer is in effect for a fixed time period and includes a first price at the commencement of the fixed time period and a second price at the end of the fixed time period. A price-time relationship for the ad avail is specified by the seller such that the price of the ad avail varies over the fixed time period. The server node matches the request to the offer at time t1 during the fixed time period and the server node computes a price for the ad avail based on t1 using the price-time function.

Abstract: A method of settling accounts of buyers and sellers of telecommunication services by an online exchange system includes storing data representing a financial account of at least one seller and at least one buyer, wherein the financial account includes at least one of accounts receivable and cash receipts. A service node receives an offer to sell the services from the at least one seller and requests to buy the services from the at least one buyer. The service node then matches the offers and requests in accordance with one or more parameters specified in the offers and requests. A route table is generated based on the routes specified in the matched offers and requests and a switch node is configured based on the route table. Fees are computed based on the usage of the matched routes and the financial accounts of the at least one seller and at least one buyer based on the computed fees.

Abstract: A method settling accounts of buyers and sellers of telecommunications services by an online exchange system includes storing data representing a financial account of at least one seller and at least one buyer, wherein the financial account includes at least one of accounts receivable and cash receipts. A service node receives an offer to sell the services from the at least one seller and requests to buy the services from the at least one buyer. The service node then matches the offer and requests in accordance with one or more parameters specified in the offers and requests. A route table is generated based on the routes specified in the matched offers and requests and a switch node is configured based on the route table. Fees are computed based on the usage of the matched routes and the financial accounts of the at least one seller and at least one buyer based on the computer fees.

Abstract: A method settling accounts of buyers and sellers of telecommunications services by an online exchange system includes storing data representing a financial account of at least one seller and at least one buyer, wherein the financial account includes at least one of accounts receivable and cash receipts. A service node receives an offer to sell the services from the at least one seller and requests to buy the services from the at least one buyer. The service node then matches the offer and requests in accordance with one or more parameters specified in the offers and requests. A route table is generated based on the routes specified in the matched offers and requests and a switch node is configured based on the route table. Fees are computed based on the usage of the matched routes and the financial accounts of the at least one seller and at least one buyer based on the computer fees.