Patents by Inventor Chi-Hao Chen

Chi-Hao Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12364418
    Abstract: A method for manufacturing an implantable micro-biosensor includes the steps of: a) providing a substrate, b) forming on a first surface of the substrate a first working electrode which at least includes a first sensing section including a first conductive material, c) forming on the first surface of the substrate at least one second working electrode which at least includes a second sensing section disposed proximate to at least one side of the first sensing section, and d) forming a chemical reagent layer which at least covers the first conductive material of the first sensing section and which reacts with the analyte to produce a product.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: July 22, 2025
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Chien-Chung Chen
  • Patent number: 12097025
    Abstract: The present invention provides a measuring method for prolonging a usage lifetime of a biosensor to measure a physiological signal representative of a physiological parameter associated with an analyte in a biofluid. The biosensor includes two working electrodes at least partially covered by a chemical reagent and two counter electrodes having silver and a silver halide, and each silver halide has an initial amount.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: September 24, 2024
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Chien-Chung Chen
  • Publication number: 20240206771
    Abstract: The present invention provides a micro biosensor for reducing a measurement interference when measuring a target analyte in the biofluid, including: a substrate; a first working electrode configured on the surface, and including a first sensing section; a second working electrode configured on the surface, and including a second sensing section which is configured adjacent to at least one side of the first sensing section; and a chemical reagent covered on at least a portion of the first sensing section for reacting with the target analyte to produce a resultant. When the first working electrode is driven by a first working voltage, the first sensing section measures a physiological signal with respect to the target analyte. When the second working electrode is driven by a second working voltage, the second conductive material can directly consume the interferant so as to continuously reduce the measurement inference of the physiological signal.
    Type: Application
    Filed: March 7, 2024
    Publication date: June 27, 2024
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Pi-Hsuan Chen
  • Publication number: 20240148280
    Abstract: An implantable micro-biosensor a substrate, a first electrode, a second electrode, a third electrode, and a chemical reagent layer. The first electrode is disposed on the substrate and used as a counter electrode. The second electrode is disposed on the substrate and spaced apart from the first electrode. The third electrode is disposed on the substrate and used as a working electrode. The chemical reagent layer at least covers a sensing section of the third electrode so as to permit the third electrode to selectively cooperate with the first electrode or the first and second electrodes to measure a physiological signal in response to the physiological parameter of the analyte.
    Type: Application
    Filed: January 16, 2024
    Publication date: May 9, 2024
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Chien-Chung Chen
  • Patent number: 11974842
    Abstract: An implantable micro-biosensor a substrate, a first electrode, a second electrode, a third electrode, and a chemical reagent layer. The first electrode is disposed on the substrate and used as a counter electrode. The second electrode is disposed on the substrate and spaced apart from the first electrode. The third electrode is disposed on the substrate and used as a working electrode. The chemical reagent layer at least covers a sensing section of the third electrode so as to permit the third electrode to selectively cooperate with the first electrode or the first and second electrodes to measure a physiological signal in response to the physiological parameter of the analyte.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: May 7, 2024
    Assignee: Bionime Corporation
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Chien-Chung Chen
  • Patent number: 11950902
    Abstract: The present invention provides a micro biosensor for reducing a measurement interference when measuring a target analyte in the biofluid, including: a substrate; a first working electrode configured on the surface, and including a first sensing section; a second working electrode configured on the surface, and including a second sensing section which is configured adjacent to at least one side of the first sensing section; and a chemical reagent covered on at least a portion of the first sensing section for reacting with the target analyte to produce a resultant. When the first working electrode is driven by a first working voltage, the first sensing section measures a physiological signal with respect to the target analyte. When the second working electrode is driven by a second working voltage, the second conductive material can directly consume the interferant so as to continuously reduce the measurement inference of the physiological signal.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: April 9, 2024
    Assignee: Bionime Corporation
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Pi-Hsuan Chen
  • Publication number: 20220361783
    Abstract: The present invention provides a sensing structure of a micro biosensor for performing a measurement of a physiological parameter of a target analyte of a biofluid and reducing an interference of an interferant of the biofluid on the measurement by an electrochemical reaction. The sensing structure includes: a substrate having a surface; a first working electrode configured on the surface, and including an active surface; at least one second working electrode configured on the surface and adjacent to the first working electrode, for consuming the interferant by the electrochemical reaction; and an isolated layer configured with respect to the active surface to program a diffusive distribution of the interferant when the biofluid flows through the second working electrode, wherein at least the interferant of the biofluid passes through the second working electrode over a time period and is consumed by the second working electrode by the electrochemical reaction.
    Type: Application
    Filed: July 22, 2022
    Publication date: November 17, 2022
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Pi-Hsuan Chen, Chi-Hao Chen, Heng-Chia Chang
  • Patent number: 11068775
    Abstract: A processing apparatus applied in an artificial neuron is disclosed. The processing apparatus comprises a parser, a lookup array, a summing circuit and a MAC circuit. The parser parses one of M packets to extract a non-zero weight value from a header of the one packet, to identify a plurality of bit positions with a specified digit from a payload of the one packet, and to output the non-zero weight value and the bit positions in parallel. The lookup array contains N synapse values and is indexed by the bit positions in parallel to generate a plurality of match values. The summing circuit sums up the match values to generate a sum value. The MAC circuit generates a product of the non-zero weight value and the sum value, and generates an accumulate value based on the product and at least one previous accumulate value.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: July 20, 2021
    Assignee: BRITISH CAYMAN ISLANDS INTELLIGO TECHNOLOGY INC.
    Inventors: Hong-Ching Chen, Chun-Ming Huang, Chi-Hao Chen, Tsung-Liang Chen
  • Publication number: 20210030324
    Abstract: The present invention provides a micro biosensor for reducing a measurement interference when measuring a target analyte in the biofluid, including: a substrate; a first working electrode configured on the surface, and including a first sensing section; a second working electrode configured on the surface, and including a second sensing section which is configured adjacent to at least one side of the first sensing section; and a chemical reagent covered on at least a portion of the first sensing section for reacting with the target analyte to produce a resultant. When the first working electrode is driven by a first working voltage, the first sensing section measures a physiological signal with respect to the target analyte. When the second working electrode is driven by a second working voltage, the second conductive material can directly consume the interferant so as to continuously reduce the measurement inference of the physiological signal.
    Type: Application
    Filed: July 31, 2020
    Publication date: February 4, 2021
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Pi-Hsuan Chen
  • Publication number: 20210030316
    Abstract: A method for manufacturing an implantable micro-biosensor includes the steps of: a) providing a substrate, b) forming on a first surface of the substrate a first working electrode which at least includes a first sensing section including a first conductive material, c) forming on the first surface of the substrate at least one second working electrode which at least includes a second sensing section disposed proximate to at least one side of the first sensing section, and d) forming a chemical reagent layer which at least covers the first conductive material of the first sensing section and which reacts with the analyte to produce a product.
    Type: Application
    Filed: August 3, 2020
    Publication date: February 4, 2021
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Chien-Chung Chen
  • Publication number: 20210030341
    Abstract: An implantable micro-biosensor a substrate, a first electrode, a second electrode, a third electrode, and a chemical reagent layer. The first electrode is disposed on the substrate and used as a counter electrode. The second electrode is disposed on the substrate and spaced apart from the first electrode. The third electrode is disposed on the substrate and used as a working electrode. The chemical reagent layer at least covers a sensing section of the third electrode so as to permit the third electrode to selectively cooperate with the first electrode or the first and second electrodes to measure a physiological signal in response to the physiological parameter of the analyte.
    Type: Application
    Filed: July 31, 2020
    Publication date: February 4, 2021
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Chien-Chung Chen
  • Publication number: 20210030342
    Abstract: The present invention provides a measuring method for prolonging a usage lifetime of a biosensor to measure a physiological signal representative of a physiological parameter associated with an analyte in a biofluid. The biosensor includes two working electrodes at least partially covered by a chemical reagent and two counter electrodes having silver and a silver halide, and each silver halide has an initial amount.
    Type: Application
    Filed: July 31, 2020
    Publication date: February 4, 2021
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Chien-Chung Chen
  • Patent number: 10637500
    Abstract: An acceleration apparatus applied in an artificial neuron is disclosed. The acceleration apparatus comprises an AND gate array, a first storage device, a second storage device and a multiply-accumulate (MAC) circuit. The AND gate array with plural AND gates receives a first bitmap and a second bitmap to generate an output bitmap. The first storage device stores a first payload and outputs a corresponding non-zero first element according to a first access address associated with a result of comparing the first bitmap with the output bitmap. The second storage device stores a second payload and outputs a corresponding non-zero second element according to a second access address associated with a result of comparing the second bitmap with the output bitmap. The MAC circuit calculates a dot product of two element sequences from the first storage device and the second storage device.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: April 28, 2020
    Assignee: BRITISH CAYMAN ISLANDS INTELLIGO TECHNOLOGY INC.
    Inventors: Chi-Hao Chen, Hong-Ching Chen, Chun-Ming Huang, Tsung-Liang Chen
  • Publication number: 20190115933
    Abstract: An acceleration apparatus applied in an artificial neuron is disclosed. The acceleration apparatus comprises an AND gate array, a first storage device, a second storage device and a multiply-accumulate (MAC) circuit. The AND gate array with plural AND gates receives a first bitmap and a second bitmap to generate an output bitmap. The first storage device stores a first payload and outputs a corresponding non-zero first element according to a first access address associated with a result of comparing the first bitmap with the output bitmap. The second storage device stores a second payload and outputs a corresponding non-zero second element according to a second access address associated with a result of comparing the second bitmap with the output bitmap. The MAC circuit calculates a dot product of two element sequences from the first storage device and the second storage device.
    Type: Application
    Filed: October 5, 2018
    Publication date: April 18, 2019
    Inventors: Chi-Hao Chen, Hong-Ching Chen, Chun-Ming Huang, Tsung-Liang Chen
  • Publication number: 20180285737
    Abstract: A processing apparatus applied in an artificial neuron is disclosed. The processing apparatus comprises a parser, a lookup array, a summing circuit and a MAC circuit. The parser parses one of M packets to extract a non-zero weight value from a header of the one packet, to identify a plurality of bit positions with a specified digit from a payload of the one packet, and to output the non-zero weight value and the bit positions in parallel. The lookup array contains N synapse values and is indexed by the bit positions in parallel to generate a plurality of match values. The summing circuit sums up the match values to generate a sum value. The MAC circuit generates a product of the non-zero weight value and the sum value, and generates an accumulate value based on the product and at least one previous accumulate value.
    Type: Application
    Filed: March 2, 2018
    Publication date: October 4, 2018
    Inventors: Hong-Ching CHEN, Chun-Ming HUANG, Chi-Hao CHEN, Tsung-Liang CHEN
  • Patent number: 9251056
    Abstract: A method for memory management is provided for a memory including a plurality of pages. The method comprises assigning in-use pages to in-use buckets according to use counts. The in-use buckets include a low in-use bucket for a lowest range of use counts, and a high in-use bucket for a highest range of use counts. The method comprises assigning free pages to free buckets according to use counts. The free buckets include a low free bucket for a lowest range of use counts, and a high free bucket for a highest range of use counts. The method maintains use counts for in-use pages. On a triggering event for a current in-use page, the method determines whether the use count of the current in-use page exceeds a hot swap threshold, and if so moves data in the current in-use page to a lead page in the low free bucket.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: February 2, 2016
    Assignee: Macronix International Co., Ltd.
    Inventors: Po-Chao Fang, Cheng-Yuan Wang, Hsiang-Pang Li, Chi-Hao Chen, Pi-Cheng Hsiu, Tei-Wei Kuo
  • Publication number: 20130326148
    Abstract: A method for memory management is provided for a memory including a plurality of pages. The method comprises assigning in-use pages to in-use buckets according to use counts. The in-use buckets include a low in-use bucket for a lowest range of use counts, and a high in-use bucket for a highest range of use counts. The method comprises assigning free pages to free buckets according to use counts. The free buckets include a low free bucket for a lowest range of use counts, and a high free bucket for a highest range of use counts. The method maintains use counts for in-use pages. On a triggering event for a current in-use page, the method determines whether the use count of the current in-use page exceeds a hot swap threshold, and if so moves data in the current in-use page to a lead page in the low free bucket.
    Type: Application
    Filed: October 5, 2012
    Publication date: December 5, 2013
    Inventors: Po-Chao Fang, Cheng-Yuan Wang, Hsiang-Pang Li, Chi-Hao Chen, Pi-Cheng Hsiu, Tei-Wei Kuo