Abstract: The present disclosure relates to a chimeric influenza virus hemagglutinin (HA) polypeptide, comprising one or more stem domain sequence, each having at least 60% homology with a stem domain consensus sequence of H1 subtype HA (H1 HA) and/or H5 subtype HA (H5 HA), fused with one or more globular head domain sequence, each having at least 60% homology with a globular head domain consensus sequence of H1 subtype HA (H1 HA) or H5 subtype HA (H5 HA).

Abstract: The present disclosure provides compounds of Formulas (I), (II), and pharmaceutically acceptable salts thereof. The compounds described herein are useful in treating proliferative diseases, for example, cancer (e.g., lung cancer), and infectious diseases (e.g., bacterial infections).

Abstract: The present disclosure relates to a chimeric influenza virus hemagglutinin (HA) polypeptide, comprising one or more stem domain sequence, each having at least 60% homology with a stem domain consensus sequence of H1 subtype HA (H1 HA) and/or H5 subtype HA (H5 HA), fused with one or more globular head domain sequence, each having at least 60% homology with a globular head domain consensus sequence of H1 subtype HA (H1 HA) or H5 subtype HA (H5 HA).

Abstract: A system for resolving at least one use parameter relating to a firing of a machinegun or of a semi-automatic firearm having a receiver, an action within the receiver and that includes a piston, and a buffer tube that receives at least a portion of the piston during a cycling of the action in response to a recoil. The system includes: a display configured to display at least an indication of at least one use parameter; a sensor disposed in the buffer tube, the sensor sensing a cycling of an action via movement of the piston in the buffer tube; a processor that receives sensed data from the sensor and, based on the received sensed data, calculates the at least one use parameter, the processor causing the display to display the at least an indication; and a power source disposed in the stock or the display and energizing the sensor, the processor, and the display.

Abstract: A system for resolving at least one use parameter relating to a firing of a machinegun or of a semi-automatic firearm having a receiver, an action within the receiver and that includes a piston, and a buffer tube that receives at least a portion of the piston during a cycling of the action in response to a recoil. The system includes: a display configured to display at least an indication of at least one use parameter; a sensor disposed in the buffer tube, the sensor sensing a cycling of an action via movement of the piston in the buffer tube; a processor that receives sensed data from the sensor and, based on the received sensed data, calculates the at least one use parameter, the processor causing the display to display the at least an indication; and a power source disposed in the stock or the display and energizing the sensor, the processor, and the display.