Patents by Inventor Chi Le

Chi Le has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250320532
    Abstract: Methods for the preparation and isolation of malonic acid, a salt or a diesters thereof, preferably bio-based versions of the foregoing are provided.
    Type: Application
    Filed: June 10, 2022
    Publication date: October 16, 2025
    Inventors: Nicholas Ohler, Chi Le, Daniel Blackburn, Owen Budavich, Drew Ross, Johan Van Walsem, Jeffrey Dietrich
  • Publication number: 20250269366
    Abstract: Provided herein is a process of ion exchange comprising malonic acid or a salt thereof and a cation or an anion cation exchange resin. The ion exchange is accomplished, e.g., and without limitation by continuous ion exchange. A valve and resin bed configuration is useful in this regard. The malonic acid separated by ion exchange is esterified, e.g., by Fisher esterification by using an acid and an alcohol.
    Type: Application
    Filed: September 20, 2021
    Publication date: August 28, 2025
    Applicant: LYGOS, INC.
    Inventors: Nicholas Ohler, Johan Van Walsem, Chi Le, Kelvin Shing, Daniel Blackburn, Owen Budavich
  • Publication number: 20230279452
    Abstract: Provided herein are processes, including semi-synthetic, and synthetic processes for preparing cannabinoids, and cannabinoid compositions provided thereby.
    Type: Application
    Filed: February 9, 2021
    Publication date: September 7, 2023
    Inventors: NICHOLAS OHLER, JASON POULOS, CHI LE, NEIL MCALPINE, ANTHONY FARINA
  • Publication number: 20230174460
    Abstract: The present disclosure provides compounds of formula (I), (II), and (Ia): Methods of preparing these molecules and their use for treatment of Parkinson's Disease are described.
    Type: Application
    Filed: April 21, 2021
    Publication date: June 8, 2023
    Inventors: Emily Balskus, Chi Le
  • Publication number: 20220119821
    Abstract: Methods and materials related to producing aspartic acid, ?-alanine and salts of each thereof are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, methods and materials for producing aspartic acid by direct fermentation from sugars are disclosed.
    Type: Application
    Filed: June 24, 2019
    Publication date: April 21, 2022
    Inventors: Jeffrey A. Dietrich, Mario Ouellet, Ee-Been Goh, Chi Le, Kelvin Shing, Drew Ross, Daniel Blackburn
  • Publication number: 20100081563
    Abstract: The present invention pertains to the addition of a carboxylic acid, preferably formic acid or acetic acid, to a washcoat and/or overcoat slurry to improve the properties of the slurry, including adhesion of the slurry to a substrate. The present invention provides for the reduction in oxide solid loss, increase in oxide solid pickup, and a more efficient method of producing washcoat and/or overcoat slurries.
    Type: Application
    Filed: September 26, 2008
    Publication date: April 1, 2010
    Inventors: Andrew Edgar-Beltran, Stephen J. Golden, Mark Jarand, Chi Le
  • Publication number: 20070049187
    Abstract: An apparatus is electrically powered and the automatically forces acting method uses for open oyster shells, whichese serves as a catalyst from the torque rotation to double pushes and pulls directions for moving up and down pressed the opener's momentum through oyster seam is open the shells. An opener is long inclined teeth blade and wedge shaped; the opener may open all sizes of oyster by the technique of the normal force or the combining of the shearing and sliding forces. At almost the same of the normal force technique above; but in this techniques of the forces combination, either shell for forcing must parallel to the angle of the opener. When the opener's momentum coming down pushes on the shell; the shearing deformation exerts a sliding frictional force to broke the oyster eye, the shells slides off each other; the oyster shells is opened.
    Type: Application
    Filed: July 20, 2005
    Publication date: March 1, 2007
    Inventor: Chi Le