Abstract: The present invention discloses the combination use of arsenic-containing pharmaceutical composition and radiation therapy on cutaneous metastases.

Abstract: The invention relates to a pharmaceutical composition for the treatment of skin neoplasm, which comprises a therapeutically effective amount of arsenic trioxide and a pharmaceutically acceptable carrier. Furthermore, the invention also relates to a method of treating skin neoplasm in a human by administering to a human in need thereof a therapeutically effective amount of a pharmaceutical composition comprising arsenic trioxide.

Abstract: A process for the large scale production of a liposome suspension, in which three selected lipid compounds in a predetermined ratio are dissolved in an alcohol solvent to form a mixture, which, in turn, is directly admixed with an aqueous ammonium sulfate solution in a predetermined ratio. The resultant mixture is subjected to a pore-extrusion treatment, followed by dialyzing the pore-extruded mixture with a 5% to 15% sucrose aqueous solution, such that a liposome suspension containing liposome particles suspended in the liposome suspension is obtained. The thus obtained liposome suspension can be used to encapsulate a selected drug, in particular doxorubicin.