Patents by Inventor Chi-Ming Che

Chi-Ming Che has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10937975
    Abstract: An organometallic compound represented by Formula 1: wherein, in Formula 1, groups and variables are the same as described in the specification.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: March 2, 2021
    Assignees: SAMSUNG ELECTRONICS CO., LTD., VERSITECH LIMITED
    Inventors: Yoonhyun Kwak, Chi Ming Che, Whail Choi, Tsz Lung Lam, So Ming Tong
  • Patent number: 10851127
    Abstract: Provided herein are platinum complexes of Formula I: Also, provided are methods of making the platinum complexes of Formula I and apparatuses that include platinum complexes of Formula I. The apparatuses can include near infrared organic light emitting devices.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: December 1, 2020
    Assignee: The University of Hong Kong
    Inventors: Chi Ming Che, Chun Lam Kwong
  • Publication number: 20200194690
    Abstract: Described are to tungsten(VI) emitters. These materials can be used to fabricate OLEDs.
    Type: Application
    Filed: August 11, 2017
    Publication date: June 18, 2020
    Inventor: Chi Ming Che
  • Patent number: 10672999
    Abstract: Gold(III) emitters showing high emission quantum efficiency and stable in thermal deposition process are described. High performance OLEDs can be fabricated from these emitters.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: June 2, 2020
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventor: Chi-Ming Che
  • Patent number: 10577387
    Abstract: Provided herein is a method of synthesis of Pt(II) complexes, a pharmaceutical composition comprises thereof. Also provided herein are the methods for the treatment and prevention of cancer/tumor in patients in need thereof by the administration of the Pt(II) complexes. Also provided is a method of detecting the Pt(II) complex in a biological system. Also provided is a method of making the Pt(II) complex The Pt(II) complexes possess anticancer activity such as the induction of cell death, inhibition of cellular proliferation, and inhibition of tumor growth in vivo.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: March 3, 2020
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventors: Chi Ming Che, Sin Ki Fung, Tian Feng Chen
  • Publication number: 20200048291
    Abstract: Provided herein is a method of synthesis of Pt(II) complexes, a pharmaceutical composition comprises thereof. Also provided herein are the methods for the treatment and prevention of cancer/tumor in patients in need thereof by the administration of the Pt(II) complexes. Also provided is a method of detecting the Pt(II) complex in a biological system. Also provided is a method of making the Pt(II) complex The Pt(II) complexes possess anticancer activity such as the induction of cell death, inhibition of cellular proliferation, and inhibition of tumor growth in vivo.
    Type: Application
    Filed: August 9, 2018
    Publication date: February 13, 2020
    Inventors: Chi Ming CHE, Sin Ki FUNG, Tian Feng CHEN
  • Patent number: 10378046
    Abstract: Disclosed are methods of using d8 square planar metal complexes containing tridentate ?-conjugated ligands and ancillary ligand of N-heterocyclic carbene or di-phosphine ligand to target mismatched DNA. Targeting of mismatched DNA can be revealed by monitoring the differences in emission enhancement of metal complexes toward mismatched DNA and matched DNA; or the gradually heat release from isothermal titration calorimetry (ITC) when complexes bind toward mismatch DNA; or the significant increase in melting temperature of the mismatched DNA after adding complexes.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: August 13, 2019
    Assignee: The University of Hong Kong
    Inventors: Chi Ming Che, Sin Ki Fung, Taotao Zou
  • Patent number: 10361382
    Abstract: Described herein are compounds that are platinum emitters and, more particularly compounds that are platinum emitters of blue light and their applications in blue emitting organic light-emitting diodes (OLED). Also disclosed herein are devices that comprise the platinum emitters and methods of making and using the platinum emitters.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: July 23, 2019
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventor: Chi Ming Che
  • Patent number: 10243154
    Abstract: The current invention relates to novel platinum(II) based organometallic materials. These materials show high emission quantum efficiencies and low self-quenching constant. Also provided are high efficiency, green to orange emitting organic light-emitting diode (OLED) that are fabricated using platinum(II) based organometallic materials as the light-emitting material. The organometallic materials of the invention are soluble in common solvents; therefore, solution process methods such as spin coating and printing can be used for device fabrication. The devices fabricated from these materials show low efficiency roll-off.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: March 26, 2019
    Assignee: Versitech Limited
    Inventors: Chi Ming Che, Chi Fai Kui, Chi Chung Kwok
  • Publication number: 20190074454
    Abstract: An organometallic compound represented by Formula 1: wherein, in Formula 1, groups and variables are the same as described in the specification.
    Type: Application
    Filed: July 9, 2018
    Publication date: March 7, 2019
    Inventors: Yoonhyun Kwak, Chi Ming CHE, Whail CHOI, Tsz Lung LAM, So Ming TONG
  • Publication number: 20180323384
    Abstract: Described herein are novel platinum(II) emitters. These materials show high emission quantum efficiency, a low self-quenching constant and are stable in thermal deposition process. Organic light-emitting diodes (OLEDs) fabricated from these materials can have pure green emission, high efficiency and low efficiency roll-off.
    Type: Application
    Filed: July 16, 2018
    Publication date: November 8, 2018
    Inventors: Chi Ming Che, Chi Fai Kui, Chi Chung Kwok
  • Publication number: 20180258119
    Abstract: Provided herein are platinum complexes of Formula I: Also, provided are methods of making the platinum complexes of Formula I and apparatuses that include platinum complexes of Formula I. The apparatuses can include near infrared organic light emitting devices.
    Type: Application
    Filed: March 7, 2018
    Publication date: September 13, 2018
    Inventors: CHI MING CHE, CHUN LAM KWONG
  • Publication number: 20180233680
    Abstract: The current invention relates to novel platinum(II) based organometallic materials. These materials show high emission quantum efficiencies and low self-quenching constant. Also provided are high efficiency, green to orange emitting organic light-emitting diode (OLED) that are fabricated using platinum(II) based organometallic materials as the light-emitting material. The organometallic materials of the invention are soluble in common solvents; therefore, solution process methods such as spin coating and printing can be used for device fabrication. The devices fabricated from these materials show low efficiency roll-off.
    Type: Application
    Filed: April 11, 2018
    Publication date: August 16, 2018
    Inventors: Chi Ming CHE, Chi Fai KUI, Chi Chung KWOK
  • Patent number: 10038153
    Abstract: Described herein are novel platinum(II) emitters. These materials show high emission quantum efficiency, a low self-quenching constant, and are stable in thermal deposition processes. Organic light-emitting diodes (OLEDs) fabricated from these materials can have pure green emission, high efficiency and low efficiency roll-off.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: July 31, 2018
    Assignee: VERSITECH LIMITED
    Inventors: Chi Ming Che, Chi Fai Kui, Chi Chung Kwok
  • Patent number: 10008681
    Abstract: The current invention relates to novel platinum(II) based organometallic materials. These materials show high emission quantum efficiencies and low self-quenching constant. Also provided are high efficiency, green to orange emitting organic light-emitting diode (OLED) that are fabricated using platinum(II) based organometallic materials as the light-emitting material. The organometallic materials of the invention are soluble in common solvents; therefore, solution process methods such as spin coating and printing can be used for device fabrication. The devices fabricated from these materials show low efficiency roll-off.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: June 26, 2018
    Assignee: VERSITECH LIMITED
    Inventors: Chi Ming Che, Chi Fai Kui, Chi Chung Kwok
  • Patent number: 9822139
    Abstract: The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: November 21, 2017
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventors: Chi Ming Che, Raymond Wai-Yin Sun, Lok Fung Chow, Jing Yan
  • Publication number: 20170207389
    Abstract: Described herein are compounds that are platinum emitters and, more particularly compounds that are platinum emitters of blue light and their applications in blue emitting organic light-emitting diodes (OLED). Also disclosed herein are devices that comprise the platinum emitters and methods of making and using the platinum emitters.
    Type: Application
    Filed: January 12, 2017
    Publication date: July 20, 2017
    Inventor: Chi Ming CHE
  • Publication number: 20170157261
    Abstract: Disclosed are conjugates, compositions, and methods that include or use one or more gold(III) porphyrin complexes. Preferred conjugates are gold(III) porphyrin-poly(ethylene glycol) (PEG) conjugates. Preferred compositions and methods include or use such gold(III) porphyrin-PEG conjugates. Disclosed is a method for treatment of cancer comprising administering to a human in need of such treatment a composition containing a therapeutically effective amount of gold(III) porphyrin-poly(ethylene glycol) (PEG) conjugates. The gold(III) porphyrin-PEG conjugates can be in the form of nanostructures formed by self-assembly of the gold(III) porphyrin-PEG conjugates; or nanocomposites formed by encapsulation of other therapeutic agents by the nanostructures of gold(III) porphyrin-PEG conjugates.
    Type: Application
    Filed: December 2, 2016
    Publication date: June 8, 2017
    Inventors: Chi Ming Che, Yik Sham Clive Chung
  • Publication number: 20160369354
    Abstract: Disclosed are methods of using d8 square planar metal complexes containing tridentate ?-conjugated ligands and ancillary ligand of N-heterocyclic carbene or di-phosphine ligand to target mismatched DNA. Targeting of mismatched DNA can be revealed by monitoring the differences in emission enhancement of metal complexes toward mismatched DNA and matched DNA; or the gradually heat release from isothermal titration calorimetry (ITC) when complexes bind toward mismatch DNA; or the significant increase in melting temperature of the mismatched DNA after adding complexes.
    Type: Application
    Filed: May 27, 2016
    Publication date: December 22, 2016
    Inventors: Chi Ming Che, Sin Ki Fung, Taotao Zou
  • Publication number: 20160301020
    Abstract: Gold(III) emitters showing high emission quantum efficiency and stable in thermal deposition process are described. High performance OLEDs can be fabricated from these emitters.
    Type: Application
    Filed: April 13, 2016
    Publication date: October 13, 2016
    Inventor: Chi-Ming Che