Patents by Inventor Chi Shung Brian To

Chi Shung Brian To has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for activation and conjugation of biomolecules
    Patent number: 9254336
    Abstract: The present invention is directed to a method for producing a biomolecule conjugate where the method is integrated into a single unit operation.
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: February 9, 2016
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Jens H. Vogel, Chi Shung Brian To, Carolina Lucia Bianco
  • Method for Activation and Conjugation of Biomolecules
    Publication number: 20130040362
    Abstract: The present invention is directed to a method for producing a biomolecule conjugate where the method is integrated into a single unit operation.
    Type: Application
    Filed: February 21, 2011
    Publication date: February 14, 2013
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Jens H. Vogel, Chi Shung Brian To, Carolina Lucia Bianco
  • Methods of adenovirus purification
    Patent number: 7326555
    Abstract: A process for purifying virus particles, especially recombinant adenovirus vector particles, is presented. The process relies on various combinations of cell lysis, detergent-based precipitation of host cell contaminants away from the virus, depth filtration or centrifugation, ultrafiltration, nuclease digestion and chromatography to robustly and economically produce highly purified product. This process results in contaminating DNA levels which are consistently below detectable levels.
    Type: Grant
    Filed: May 13, 2003
    Date of Patent: February 5, 2008
    Assignee: Merck & Co., Inc.
    Inventors: John O. Konz, Jr., Ann L. Lee, Chi Shung Brian To, Aaron R Goerke