Abstract: An apparatus and method for performing analysis and identification of molecules have been presented. In one embodiment, a portable molecule analyzer includes a sample input/output connection to receive a sample, a nanopore-based sequencing chip to perform analysis on the sample substantially in real-time, and an output interface to output result of the analysis.

Abstract: An apparatus and method for performing analysis and identification of molecules have been presented. In one embodiment, a portable molecule analyzer includes a sample input/output connection to receive a sample, a nanopore-based sequencing chip to perform analysis on the sample substantially in real-time, and an output interface to output result of the analysis.

Abstract: Nicking molecules nick or cleave a polynucleotide molecule translocating through a real-time single-base-read nanopore sequencing device that achieves real-time single-base-read sequencing by probing individual bases of the polynucleotide molecule. The polynucleotide molecule is guided to enter and translocate through a nanopore of the nanopore sequencing device. A target sequence is determined for a nick or cleave, and the polynucleotide molecule is sequenced by the nanopore sequencing device. After reading the target sequence, an external excitation is applied to trigger one or more nicking molecules and thereby nick or cleave the polynucleotide at a location adjacent to the one or more nicking molecules. In the case of a requirement to further nick or cleave the same target sequence, the process is continued, and in the case of a requirement to nick or cleave another target sequence, another target sequence is determined.

Abstract: An apparatus and method for performing analysis and identification of molecules have been presented. In one embodiment, a portable molecule analyzer includes a sample input/output connection to receive a sample, a nanopore-based sequencing chip to perform analysis on the sample substantially in real-time, and an output interface to output result of the analysis.

Abstract: An apparatus and method for performing analysis and identification of molecules have been presented. In one embodiment, a portable molecule analyzer includes a sample input/output connection to receive a sample, a nanopore-based sequencing chip to perform analysis on the sample substantially in real-time, and an output interface to output result of the analysis.